Search Results - "Tomlinson, Sophia"
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Targeted Brain Delivery of Dendrimer-4-Phenylbutyrate Ameliorates Neurological Deficits in a Long-Term ABCD1-Deficient Mouse Model of X-Linked Adrenoleukodystrophy
Published in Neurotherapeutics (01-01-2023)“…X-linked adrenoleukodystrophy (ALD) is a genetic disorder that presents neurologically as either a rapid and fatal cerebral demyelinating disease in childhood…”
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Glial restricted precursor delivery of dendrimer N-acetylcysteine promotes migration and differentiation following transplant in mouse white matter injury model
Published in Nanoscale (14-08-2020)“…Oligodendrocyte replacement using glial restricted precursors (GRPs) is a promising avenue for the treatment of acquired or genetic white matter disorders;…”
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Neuronal ablation of mt-AspRS in mice induces immune pathway activation prior to severe and progressive cortical and behavioral disruption
Published in Experimental neurology (01-04-2020)“…Leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation (LBSL) is a rare, slowly progressive white matter disease caused by…”
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The Musashi RNA binding proteins direct the translational activation of key pituitary mRNAs
Published in Scientific reports (11-03-2024)“…The pituitary functions as a master endocrine gland that secretes hormones critical for regulation of a wide variety of physiological processes including…”
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PMON29 A Comparative Analysis of Musashi-Dependent Control of Mouse and Human Pituitary mRNA Translation
Published in Journal of the Endocrine Society (01-11-2022)“…Abstract Specialized cell lineages within the anterior pituitary produce specific hormones which, in turn, regulate diverse biological processes ranging from…”
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RF01 | PMON46 Regulation of the Pituitary Cell Lineage Regulator Prop1 by the Stem Cell Determinant Musashi
Published in Journal of the Endocrine Society (01-11-2022)“…Abstract The pituitary gland controls responses to changing physiological requirements during growth, pregnancy, puberty, and stress. Synthesis and secretion…”
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RF25 | PMON50 Insight into Integrated Control of Pituitary Function Revealed Through Analysis of Musashi Target mRNAs
Published in Journal of the Endocrine Society (01-11-2022)“…Abstract The anterior pituitary controls growth, metabolism, reproduction and stress responses through the synthesis and secretion of specific hormones…”
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