Search Results - "Tomley, Fiona M"
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Re-calculating the cost of coccidiosis in chickens
Published in Veterinary research (Paris) (14-09-2020)“…Coccidiosis, caused by Eimeria species parasites, has long been recognised as an economically significant disease of chickens. As the global chicken population…”
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Effects of Eimeria tenella infection on chicken caecal microbiome diversity, exploring variation associated with severity of pathology
Published in PloS one (21-09-2017)“…Eimeria species cause the intestinal disease coccidiosis, most notably in poultry. While the direct impact of coccidiosis on animal health and welfare is…”
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3
Livestock infectious diseases and zoonoses
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (27-09-2009)“…Infectious diseases of livestock are a major threat to global animal health and welfare and their effective control is crucial for agronomic health, for…”
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Poultry Coccidiosis: Design and Interpretation of Vaccine Studies
Published in Frontiers in veterinary science (26-02-2020)“…infection impacts upon chicken welfare and economic productivity of the poultry sector. Live coccidiosis vaccines for chickens have been available for almost…”
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Cellular electron tomography of the apical complex in the apicomplexan parasite Eimeria tenella shows a highly organised gateway for regulated secretion
Published in PLoS pathogens (11-07-2022)“…The apical complex of apicomplexan parasites is essential for host cell invasion and intracellular survival and as the site of regulated exocytosis from…”
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Comparative study of Eimeria tenella development in different cell culture systems
Published in PloS one (18-07-2024)“…Cell culture systems have long been recognised as great resources to mitigate the use of animals in research, offering effective solutions for replacement or…”
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A selective review of advances in coccidiosis research
Published in Advances in parasitology (2013)“…Coccidiosis is a widespread and economically significant disease of livestock caused by protozoan parasites of the genus Eimeria. This disease is worldwide in…”
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Microbial diversity and community composition of caecal microbiota in commercial and indigenous Indian chickens determined using 16s rDNA amplicon sequencing
Published in Microbiome (23-06-2018)“…The caecal microbiota plays a key role in chicken health and performance, influencing digestion and absorption of nutrients, and contributing to defence…”
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Population, genetic, and antigenic diversity of the apicomplexan Eimeria tenella and their relevance to vaccine development
Published in Proceedings of the National Academy of Sciences - PNAS (22-09-2015)“…The phylum Apicomplexa includes serious pathogens of humans and animals. Understanding the distribution and population structure of these protozoan parasites…”
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A Novel Whole Yeast-Based Subunit Oral Vaccine Against Eimeria tenella in Chickens
Published in Frontiers in immunology (02-02-2022)“…Cheap, easy-to-produce oral vaccines are needed for control of coccidiosis in chickens to reduce the impact of this disease on welfare and economic…”
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Vaccination with transgenic Eimeria tenella expressing Eimeria maxima AMA1 and IMP1 confers partial protection against high-level E. maxima challenge in a broiler model of coccidiosis
Published in Parasites & vectors (10-07-2020)“…Poultry coccidiosis is a parasitic enteric disease with a highly negative impact on chicken production. In-feed chemoprophylaxis remains the primary method of…”
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Refractile bodies of Eimeria tenella are proteinaceous membrane-less organelles that undergo dynamic changes during infection
Published in Frontiers in cellular and infection microbiology (09-03-2023)“…Refractile bodies (RB) are large membrane-less organelles (MLO) of unknown function found as a prominent mismatched pair within the sporozoite stages of all…”
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Phenotypic and genetic variation in the response of chickens to Eimeria tenella induced coccidiosis
Published in Genetics selection evolution (Paris) (21-11-2018)“…Coccidiosis is a major contributor to losses in poultry production. With emerging constraints on the use of in-feed prophylactic anticoccidial drugs and the…”
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Multi-omics analysis reveals regime shifts in the gastrointestinal ecosystem in chickens following anticoccidial vaccination and Eimeria tenella challenge
Published in mSystems (22-10-2024)“…Coccidiosis, caused by parasites, significantly impacts poultry farm economics and animal welfare. Beyond its direct impact on health, infection disrupts…”
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Do All Coccidia Follow the Same Trafficking Rules?
Published in Life (Basel, Switzerland) (31-08-2021)“…The Coccidia are a subclass of the Apicomplexa and include several genera of protozoan parasites that cause important diseases in humans and animals, with…”
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Quantitative real-time PCR (qPCR) for Eimeria tenella replication — Implications for experimental refinement and animal welfare
Published in Parasitology international (01-10-2015)“…Abstract The Eimeria species are highly pathogenic parasites of chickens. Research aimed at reducing their impact is hindered by a lack of non-subjective,…”
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Characterization of novel microneme adhesive repeats (MAR) in Eimeria tenella
Published in Parasites & vectors (17-10-2017)“…The phylum Apicomplexa comprises a wide variety of parasites of significant medical and economic relevance. These parasites have extremely different host and…”
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Revisiting the Economic Impacts of Eimeria and Its Control in European Intensive Broiler Systems With a Recursive Modeling Approach
Published in Frontiers in veterinary science (05-11-2020)“…Ionophore compounds active against species are widely used in intensive broiler systems and have formed the backbone of coccidiosis control for almost 50…”
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Proteomic comparison of four Eimeria tenella life-cycle stages: Unsporulated oocyst, sporulated oocyst, sporozoite and second-generation merozoite
Published in Proteomics (Weinheim) (01-10-2009)“…We report the proteomes of four life-cycle stages of the Apicomplexan parasite Eimeria tenella. A total of 1868 proteins were identified, with 630, 699, 845…”
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Securing poultry production from the ever-present Eimeria challenge
Published in Trends in parasitology (01-01-2014)“…Highlights • Coccidiosis is a major and recurring problem for livestock productivity and food security. • Current control methods are not perfect. • Progress…”
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