Search Results - "Tomita, Yasuyuki"

Long-term intake of Lactobacillus paracasei KW3110 prevents age-related circadian locomotor activity and changes in gut metabolism in physiologically aged mice by Morita, Yuji, Jounai, Kenta, Tomita, Yasuyuki, Maruyama, Mitsuo

“…Aging involves age-progressive loss of physiological functions in organs and tissues. We previously showed that Lactobacillus paracasei KW3110 suppressed…”
Get full text

DNA module platform for developing colorimetric aptamer sensors by Tomita, Yasuyuki, Morita, Yuji, Suga, Hiroaki, Fujiwara, Daisuke

“…Here we present a DNA module platform for developing simple aptamer sensors based on a microarray format combined with secondary structure prediction in…”
Get full text

Characterization of genomic DNA of lactic acid bacteria for activation of plasmacytoid dendritic cells by Horie, Akira, Tomita, Yasuyuki, Ohshio, Konomi, Fujiwara, Daisuke, Fujii, Toshio

“…Lactococcus lactis strain Plasma (LC-Plasma) possesses strong stimulatory activity for plasmacytoid dendritic cells (pDCs) via the TLR9-Myd88 pathway. To…”
Get full text

Long-term intake of Lactobacillus paracasei KW3110 prevents age-related chronic inflammation and retinal cell loss in physiologically aged mice by Morita, Yuji, Jounai, Kenta, Sakamoto, Akihiko, Tomita, Yasuyuki, Sugihara, Yoshihiko, Suzuki, Hiroaki, Ohshio, Konomi, Otake, Masato, Fujiwara, Daisuke, Kanauchi, Osamu, Maruyama, Mitsuo

“…Age-related chronic inflammation is a major risk factor for the incidence and prevalence of age-related diseases, including infectious and neurodegenerative…”
Get full text

Genome and transcriptome analysis of the food-yeast Candida utilis by Tomita, Yasuyuki, Ikeo, Kazuho, Tamakawa, Hideyuki, Gojobori, Takashi, Ikushima, Shigehito

“…The industrially important food-yeast Candida utilis is a Crabtree effect-negative yeast used to produce valuable chemicals and recombinant proteins. In the…”
Get full text

Identification of Novel Candidate Genes for Treatment Response to Risperidone and Susceptibility for Schizophrenia: Integrated Analysis Among Pharmacogenomics, Mouse Expression, and Genetic Case-Control Association Approaches by Ikeda, Masashi, Tomita, Yasuyuki, Mouri, Akihiro, Koga, Minori, Okochi, Tomo, Yoshimura, Reiji, Yamanouchi, Yoshio, Kinoshita, Yoko, Hashimoto, Ryota, Williams, Hywel J, Takeda, Masatoshi, Nakamura, Jun, Nabeshima, Toshitaka, Owen, Michael J, O'Donovan, Michael C, Honda, Hiroyuki, Arinami, Tadao, Ozaki, Norio, Iwata, Nakao

“…Background Pharmacogenomic approaches based on genomewide sets of single nucleotide polymorphisms (SNPs) are now feasible and offer the potential to uncover…”
Get full text

Metabolomic and Transcriptomic Analysis for Rate-Limiting Metabolic Steps in Xylose Utilization by Recombinant Candida utilis by TAMAKAWA, Hideyuki, TOMITA, Yasuyuki, YOKOYAMA, Aki, KONOEDA, Yuki, IKUSHIMA, Shigehito, YOSHIDA, Satoshi

“…We have reported that a recombinant Candida utilis strain expressing a Candida shehatae xylose reductase K275R/N277D, a C. shehatae xylitol dehydrogenase, and…”
Get full text

Screening of peptides with a high affinity to bile acids using peptide arrays and a computational analysis by Takeshita, Toshikazu, Okochi, Mina, Kato, Ryuji, Kaga, Chiaki, Tomita, Yasuyuki, Nagaoka, Satoshi, Honda, Hiroyuki

“…Bile acid binding peptides have attracted attention for the improvement and prevention of hypercholesterolemia. In this study, screening of bile acid high…”
Get full text

Artificial neural network approach for selection of susceptible single nucleotide polymorphisms and construction of prediction model on childhood allergic asthma by Tomita, Yasuyuki, Tomida, Shuta, Hasegawa, Yuko, Suzuki, Yoichi, Shirakawa, Taro, Kobayashi, Takeshi, Honda, Hiroyuki

“…Screening of various gene markers such as single nucleotide polymorphism (SNP) and correlation between these markers and development of multifactorial disease…”
Get full text

Computationally assisted screening and design of cell-interactive peptides by a cell-based assay using peptide arrays and a fuzzy neural network algorithm by Kaga, Chiaki, Okochi, Mina, Tomita, Yasuyuki, Kato, Ryuji, Honda, Hiroyuki

“…We developed a method of effective peptide screening that combines experiments and computational analysis. The method is based on the concept that screening…”
Get full text

Acute onset of rheumatoid arthritis associated with administration of a dipeptidyl peptidase-4 (DPP-4) inhibitor to patients with diabetes mellitus by Sasaki, Takashi, Hiki, Yoshito, Nagumo, Sae, Ikeda, Rina, Kimura, Haruka, Yamashiro, Kenji, Gojo, Atsushi, Saito, Tatsuhiko, Tomita, Yasuyuki, Utsunomiya, Kazunori

“…We describe the first case of a 63-year-old male patient with type 2 diabetes mellitus who was newly diagnosed with definitive rheumatoid arthritis (RA)…”
Get full text

Cancer DNA Microarray Analysis Considering Multi-subclass with Graph-based Clustering Method by Kawamura, Takashi, Mutoh, Hironori, Tomita, Yasuyuki, Kato, Ryuji, Honda, Hiroyuki

“…It is well known that various genes related to cell cycle, cell–cell adhesion, and transcriptional regulation cause the onset of cancer. Moreover,…”
Get full text

Association study between Apolipoprotein L and schizophrenia by exhaustive and rule-based combination analysis for identification of multilocus interactions by Tomita, Yasuyuki, Ikeda, Masashi, Mutoh, Hironori, Inada, Toshiya, Iwata, Nakao, Ozaki, Norio, Honda, Hiroyuki

“…Several single marker association and haplotypic analyses have been performed to identify susceptible genes for various common diseases, but these approaches…”
Get full text

A motif detection and classification method for peptide sequences using genetic programming by Tomita, Yasuyuki, Kato, Ryuji, Okochi, Mina, Honda, Hiroyuki

“…An exploration of common rules (property motifs) in amino acid sequences has been required for the design of novel sequences and elucidation of the…”
Get full text

Abnormal IL-1 Receptor Antagonist Production in Patients with Polymyositis and Dermatomyositis by SON, Kazue, TOMITA, Yasuyuki, SHIMIZU, Takako, NISHINARITA, Susumu, SAWADA, Shigemasa, HORIE, Takashi

“…Objective To examine the relationship between serum levels of interleukin-1 receptor antagonist (IL-1Ra) and its gene expression in peripheral blood…”
Get full text

Effectiveness and safety of subcutaneous abatacept in biologic-naïve RA patients at Week 52: A Japanese multicentre investigational study (ORIGAMI study) by Tamura, Naoto, Azuma, Takanori, Misaki, Kenta, Yamaguchi, Rei, Hirano, Fuminori, Sugiyama, Eiji, Kanai, Daisuke, Murakawa, Yohko, Oribe, Motohiro, Kimata, Takahito, Aoki, Kazutoshi, Sugiura, Tomoko, Takasugi, Koji, Takakubo, Yuya, Tomita, Yasuyuki, Isozaki, Takeo, Nanki, Toshihiro, Katsuyama, Naooki, Kuroiwa, Takanori, Oshikawa, Hideto, Kaneko, Motohide, Fujinaga, Hiroshi, Saito, Kiwamu, Tanaka, Eiichi, Inoue, Eisuke, Yoshizawa, Yuri, Matsumoto, Shigeru, Yamanaka, Hisashi, Harigai, Masayoshi

“…To evaluate the effectiveness and safety of abatacept over 52 weeks in biologic-naïve rheumatoid arthritis (RA) patients with moderate disease activity in the…”
Get full text

Identification and characterization of Candida utilis multidrug efflux transporter CuCdr1p by Watanasrisin, Wittawan, Iwatani, Shun, Oura, Takahiro, Tomita, Yasuyuki, Ikushima, Shigehiro, Chindamporn, Ariya, Niimi, Masakazu, Niimi, Kyoko, Lamping, Erwin, Cannon, Richard D., Kajiwara, Susumu

“…The edible, nitrate assimilating, yeast Candida utilis is a commercial food additive, and it is a potentially useful host for heterologous protein expression…”
Get full text

Screening of peptides with a high affinity for ZnO using spot-synthesized peptide arrays and computational analysis by Okochi, Mina, Ogawa, Masafumi, Kaga, Chiaki, Sugita, Tomoya, Tomita, Yasuyuki, Kato, Ryuji, Honda, Hiroyuki

“…Metal-binding peptides have attracted attention for their usefulness in biomineralization processes. In this work screening of high affinity peptides against…”
Get full text

Artificial Neural Network Model for Prediction of Childhood Allergic Asthma Using Single Nucleotide Polymorphism Data by Tomita, Yasuyuki, Tomida, Shuta, Suzuki, Yoichi, Shirakawa, Taro, Kobayashi, Takeshi, Honda, Hiroyuki

Get full text

Draft Genome Sequence of Lactococcus lactis subsp. lactis JCM 5805T, a Strain That Induces Plasmacytoid Dendritic Cell Activation by Fujii, Toshio, Tomita, Yasuyuki, Ikushima, Shigehito, Horie, Akira, Fujiwara, Daisuke

“…Lactococcus lactis subsp. lactis JCM 5805(T) is a dairy lactic acid bacterium that induces plasmacytoid dendritic cell (pDC) activation. Here, we report the…”
Get full text