Search Results - "Tomita, Ryoko"

Discrimination of Malignant Pleural Mesothelioma Cell Lines Using Amino Acid Metabolomics with HPLC by Tomita, Ryoko, Nishijo, Nao, Hayama, Tadashi, Fujioka, Toshihiro

“…Malignant pleural mesothelioma (MPM) is a malignancy closely associated with asbestos exposure. Although early diagnosis provides a chance of effective…”
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Deep eutectic solvent extraction of cortisol and cortisone from human saliva followed by LC-UV analysis by Nishijo, Nao, Hayama, Tadashi, Tomita, Ryoko, Fujioka, Toshihiro

“…•A deep eutectic solvent was used to extract cortisol and cortisone.•The developed method provides a suitable enrichment factor.•This allowed the analysis of…”
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Fluorous and Fluorogenic Derivatization for Selective Liquid Chromatographic Analysis of Cyanide in Human Plasma by TOMITA, Ryoko, HAYAMA, Tadashi, NISHIJO, Nao, FUJIOKA, Toshihiro

“…A liquid chromatographic (LC) method with fluorous derivatization for the determination of cyanide in human plasma is described. In this method, the cyanide…”
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Liquid Chromatographic Determination of o-Phosphoethanolamine in Human Plasma Using Fluorescent Derivatization by Tomita, Ryoko, Hayama, Tadashi, Nishijo, Nao, Sogawa, Rintaro, Shimanoe, Chisato, Fujioka, Toshihiro

“…In this study, an HPLC analysis method using pre-column derivatization with 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate (AQC) was developed for the…”
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Assessment of Anticancer Drug Effects on Pancreatic Cancer Cells under Glucose-Depleted Conditions Using Intracellular and Extracellular Amino Acid Metabolomics by Tomita, Ryoko, Todoroki, Kenichiro, Hayama, Tadashi, Yoshida, Hideyuki, Fujioka, Toshihiro, Nakashima, Manabu, Yamaguchi, Masatoshi, Nohta, Hitoshi

“…Previously, we developed a method to evaluate states of cells treated with anticancer drugs via the comprehensive analysis of amino acids, termed amino acid…”
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Amino Acid Metabolomics Using LC-MS/MS: Assessment of Cancer-Cell Resistance in a Simulated Tumor Microenvironment by TOMITA, Ryoko, TODOROKI, Kenichiro, MARUOKA, Hiroshi, YOSHIDA, Hideyuki, FUJIOKA, Toshihiro, NAKASHIMA, Manabu, YAMAGUCHI, Masatoshi, NOHTA, Hitoshi

“…We performed a comprehensive quantification of 20 amino acids in RPMI 1640 medium-cultured human colorectal adenocarcinoma cells to evaluate the efficacy of…”
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Assessment of the Efficacy of Anticancer Drugs by Amino Acid Metabolomics Using Fluorescence Derivatization-HPLC by TOMITA, Ryoko, TODOROKI, Kenichiro, MACHIDA, Kazuyuki, NISHIDA, Sho, MARUOKA, Hiroshi, YOSHIDA, Hideyuki, FUJIOKA, Toshihiro, NAKASHIMA, Manabu, YAMAGUCHI, Masatoshi, NOHTA, Hitoshi

“…Metabolomic studies conducted for evaluating cancer pathogenesis and progression by monitoring the amino acids metabolic balance hold great promise for…”
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Automatic analyzer for highly polar carboxylic acids based on fluorescence derivatization-liquid chromatography by Todoroki, Kenichiro, Nakano, Tatsuki, Ishii, Yasuhiro, Goto, Kanoko, Tomita, Ryoko, Fujioka, Toshihiro, Min, Jun Zhe, Inoue, Koichi, Toyo'oka, Toshimasa

“…A sensitive, versatile, and reproducible automatic analyzer for highly polar carboxylic acids based on a fluorescence derivatization–liquid chromatography (LC)…”
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Accurate LC-MS/MS Analysis of Diacylglycerols in Human Plasma with Eliminating Matrix Effect by Phospholipids Using Fluorous Biphasic Extraction by Nishijo, Nao, Hayama, Tadashi, Tomita, Ryoko, Fujioka, Toshihiro

“…We developed an accurate method for determining diacylglycerols (DAGs) in human plasma using a fluorous biphasic liquid–liquid extraction method, followed by…”
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Application of a fluorous derivatization method for characterization of glutathione-trapped reactive metabolites with liquid chromatography–tandem mass spectrometry analysis by Nishijo, Nao, Hayama, Tadashi, Tomita, Ryoko, Yamaguchi, Masatoshi, Fujioka, Toshihiro

“…•A fluorous derivatization method was developed for GSH-trapped metabolite analysis.•The GSH α-carboxyl group was selectively perfluoroalkylated by oxazolone…”
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Fluorous and Fluorogenic Derivatization for Selective Liquid Chromatographic Analysis of Cyanide in Human Plasma by TOMITA, Ryoko, HAYAMA, Tadashi, NISHIJO, Nao, FUJIOKA, Toshihiro

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Development of an enzyme-linked immunosorbent assay for the quantification of O-Phosphoethanolamine in human plasma by Saita, Tetsuya, Kataoka, Hiroto, Sogawa, Rintaro, Hayama, Tadashi, Tomita, Ryoko, Monji, Akira, Mizoguchi, Yoshito, Shimanoe, Chisato

“…O-Phosphoethanolamine (PEA) is an endogenous substance that is attracting interest as a biomarker for depression, and thus there is a need to develop a simple…”
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Synthesis and biological activities of some new thiazolidine derivatives containing pyrazole ring system by Nishida, Sho, Maruoka, Hiroshi, Yoshimura, Yuki, Goto, Takao, Tomita, Ryoko, Masumoto, Eiichi, Okabe, Fumi, Yamagata, Kenji, Fujioka, Toshihiro

“…As a part of systematic investigation of synthesis and biologically active compounds of thiazolidine (TZD) derivatives containing pyrazole ring system, several…”
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A Novel Synthesis of 4-Pyridazineacetic Acids via Ring Expansion of N-Cyanomethylated 3-Pyrazoline-4-acetic Acids by Masumoto, Eiichi, Maruoka, Hiroshi, Okabe, Fumi, Nishida, Sho, Tomita, Ryoko, Fujioka, Toshihiro, Yamagata, Kenji

“…A novel synthetic route to 4‐pyridazineacetic acids 10–12 has been achieved by the ring‐expansion reaction of N‐cyanomethylated 3‐pyrazoline‐4‐acetic acids…”
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Synthesis and Biological Activity of Some New Pyrazole Copper(II) Complexes by Maruoka, Hiroshi, Nishida, Sho, Kashige, Nobuhiro, Yoshimura, Yuki, Omori, Masahiko, Tomita, Ryoko, Masumoto, Eiichi, Okabe, Fumi, Miake, Fumio, Yamagata, Kenji, Fujioka, Toshihiro

“…As a part of systematic investigation of synthesis and biologically active compounds of pyrazole derivatives containing transition metal, several new pyrazole…”
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