Search Results - "Tomie Ouchida, Amanda"

Curcumin Generates Oxidative Stress and Induces Apoptosis in Adult Schistosoma mansoni Worms by de Paula Aguiar, Daniela, Brunetto Moreira Moscardini, Mayara, Rezende Morais, Enyara, Graciano de Paula, Renato, Ferreira, Pedro Manuel, Afonso, Ana, Belo, Silvana, Tomie Ouchida, Amanda, Curti, Carlos, Cunha, Wilson Roberto, Rodrigues, Vanderlei, Magalhães, Lizandra Guidi

“…Inducing apoptosis is an interesting therapeutic approach to develop drugs that act against helminthic parasites. Researchers have investigated how curcumin…”
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The role of mitochondria in metabolism and cell death by Vakifahmetoglu-Norberg, Helin, Ouchida, Amanda Tomie, Norberg, Erik

“…Mitochondria are complex organelles that play a central role in energy metabolism, control of stress responses and are a hub for biosynthetic processes. Beyond…”
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Regulation of RIPK1 activation by TAK1-mediated phosphorylation dictates apoptosis and necroptosis by Geng, Jiefei, Ito, Yasushi, Shi, Linyu, Amin, Palak, Chu, Jiachen, Ouchida, Amanda Tomie, Mookhtiar, Adnan Kasim, Zhao, Heng, Xu, Daichao, Shan, Bing, Najafov, Ayaz, Gao, Guangping, Akira, Shizuo, Yuan, Junying

“…Stimulation of TNFR1 by TNFα can promote three distinct alternative mechanisms of cell death: necroptosis, RIPK1-independent and -dependent apoptosis. How…”
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RIPK1 mediates axonal degeneration by promoting inflammation and necroptosis in ALS by Ito, Yasushi, Ofengeim, Dimitry, Najafov, Ayaz, Das, Sudeshna, Saberi, Shahram, Li, Ying, Hitomi, Junichi, Zhu, Hong, Chen, Hongbo, Mayo, Lior, Geng, Jiefei, Amin, Palak, DeWitt, Judy Park, Mookhtiar, Adnan Kasim, Florez, Marcus, Ouchida, Amanda Tomie, Fan, Jian-bing, Pasparakis, Manolis, Kelliher, Michelle A., Ravits, John, Yuan, Junying

“…Mutations in the optineurin (OPTN) gene have been implicated in both familial and sporadic amyotrophic lateral sclerosis (ALS). However, the role of this…”
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PHGDH Defines a Metabolic Subtype in Lung Adenocarcinomas with Poor Prognosis by Zhang, Boxi, Zheng, Adi, Hydbring, Per, Ambroise, Gorbatchev, Ouchida, Amanda Tomie, Goiny, Michel, Vakifahmetoglu-Norberg, Helin, Norberg, Erik

“…Molecular signatures are emerging determinants of choice of therapy for lung adenocarcinomas. An evolving therapeutic approach includes targeting metabolic…”
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Targetome analysis of chaperone-mediated autophagy in cancer cells by Hao, Yuqing, Kacal, Merve, Ouchida, Amanda Tomie, Zhang, Boxi, Norberg, Erik, Vakifahmetoglu-Norberg, Helin

“…Chaperone-mediated autophagy (CMA) is a lysosomal degradation pathway of select soluble proteins. Nearly one-third of the soluble proteins are predicted to be…”
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Effect of Mutant p53 Proteins on Glycolysis and Mitochondrial Metabolism by Eriksson, Matilda, Ambroise, Gorbatchev, Ouchida, Amanda Tomie, Lima Queiroz, Andre, Smith, Dominique, Gimenez-Cassina, Alfredo, Iwanicki, Marcin P., Muller, Patricia A., Norberg, Erik, Vakifahmetoglu-Norberg, Helin

“…TP53 is one of the most commonly mutated genes in human cancers. Unlike other tumor suppressors that are frequently deleted or acquire loss-of-function…”
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USP10 regulates the stability of the EMT-transcription factor Slug/SNAI2 by Ouchida, Amanda Tomie, Kacal, Merve, Zheng, Adi, Ambroise, Gorbatchev, Zhang, Boxi, Norberg, Erik, Vakifahmetoglu-Norberg, Helin

“…Epithelial-to-mesenchymal transition (EMT) is a fundamental mechanism governing the switch of cells from an epithelial to a motile mesenchymal-like state. This…”
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Synergistic effect of a novel autophagy inhibitor and Quizartinib enhances cancer cell death by Ouchida, Amanda Tomie, Li, Yingbo, Geng, Jiefei, Najafov, Ayaz, Ofengeim, Dimitry, Sun, Xiaoxiao, Yu, Qiang, Yuan, Junying

“…Drug combinations have been increasingly applied in chemotherapy as a strategy to enhance the efficacy of anti-cancer treatment. The appropriate drug…”
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SET protein accumulation prevents cell death in head and neck squamous cell carcinoma through regulation of redox state and autophagy by Ouchida, Amanda Tomie, Uyemura, Valéria Tudella, Queiroz, André Lima, Brauer, Verônica Soares, Cavalcanti-Neto, Marinaldo Pacífico, Sousa, Lucas Oliveira, Uyemura, Sérgio Akira, Curti, Carlos, Leopoldino, Andréia Machado

“…Molecular alterations in cell death pathways and imbalances in regulators of up- or downstream signaling pathways can lead to resistance to cell death, which…”
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CR-LAAO antileukemic effect against Bcr-Abl+ cells is mediated by apoptosis and hydrogen peroxide by Burin, Sandra Mara, Ghisla, Sandro, Ouchida, Amanda Tomie, Aissa, Alexandre Ferro, Coelho, Maria Gabriela Berzoti, Costa, Tássia Rafaella, Marsola, Ana Paula Zambuzi Cardoso, Pinto-Simões, Belinda, Antunes, Lusânia Maria Greggi, Curti, Carlos, Sampaio, Suely Vilela, de Castro, Fabíola Attié

“…Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm characterized by the presence of the Bcr-Abl tyrosine kinase protein, which confers resistance…”
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Sex differences in the development of hepatic steatosis in cafeteria diet-induced obesity in young mice by Gasparin, Fabiana Rodrigues Silva, Carreño, Fernando Olinto, Mewes, Juliana Moraes, Gilglioni, Eduardo Hideo, Pagadigorria, Clairce Luzia Salgueiro, Natali, Maria Raquel Marçal, Utsunomiya, Karina Sayuri, Constantin, Rodrigo Polimeni, Ouchida, Amanda Tomie, Curti, Carlos, Gaemers, Ingrid C., Elferink, Ronald Petrus Johannes Oude, Constantin, Jorgete, Ishii-Iwamoto, Emy Luiza

“…The present study was planned to improve our understanding about sex differences in the development of hepatic steatosis in cafeteria diet-induced obesity in…”
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Potential SET protein involvement in autophagy in cancer by Ouchida, Amanda Tomie, Uyemura, Valéria Tudella, Leopoldino, Andréia Machado, Curti, Carlos

“…Abstract only Autophagy is a process by which lysosomes degrade and recycle long‐lived proteins and cellular organelles. It degrades cellular components that…”
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