Search Results - "Tometsko, Carol"

Comparative Scoring of Micronucleated Reticulocytes in Rat Peripheral Blood by Flow Cytometry and Microscopy by Torous, Dorothea K., Hall, Nikki E., Murante, Francis G., Gleason, Sarah E., Tometsko, Carol R., Dertinger, Stephen D.

“…A flow cytometric technique for scoring the incidence of micronucleated reticulocytes in rat peripheral blood was compared to a standard microscopy-based…”
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Three-color labeling method for flow cytometric measurement of cytogenetic damage in rodent and human blood by Dertinger, Stephen D., Camphausen, Kevin, MacGregor, James T., Bishop, Michelle E., Torous, Dorothea K., Avlasevich, Svetlana, Cairns, Siân, Tometsko, Carol R., Menard, Cynthia, Muanza, Thierry, Chen, Yuhchyau, Miller, Richard K., Cederbrant, Karin, Sandelin, Kerstin, Pontén, Ingrid, Bolcsfoldi, George

“…Experiments described herein were designed to evaluate the performance characteristics of a flow cytometry‐based system that scores the incidence of peripheral…”
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Practical threshold for micronucleated reticulocyte induction observed for low doses of mitomycin C, Ara-C and colchicine by Asano, Norihide, Torous, Dorothea K., Tometsko, Carol R., Dertinger, Stephen D., Morita, Takeshi, Hayashi, Makoto

“…Micronucleus induction was studied for the DNA target clastogens mitomycin C (MMC) and 1-β-D-arabinofuranosylcytosine (Ara-C), and also the non-DNA target…”
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Micronucleated CD71-positive reticulocytes: a blood-based endpoint of cytogenetic damage in humans by Dertinger, Stephen D., Chen, Yuhchyau, Miller, Richard K., Brewer, Kelly J., Smudzin, Therese, Torous, Dorothea K., Hall, Nikki E., Olvany, Kristine A., Murante, Francis G., Tometsko, Carol R.

“…The frequency of micronuclei (also known as Howell–Jolly bodies) in peripheral blood erythrocytes of humans is extremely low due to the efficiency with which…”
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Interlaboratory validation of a CD71-based flow cytometric method (Microflow®) for the scoring of micronucleated reticulocytes in mouse peripheral blood by Torous, Dorothea K., Hall, Nikki E., Illi-Love, Anne H., Diehl, Marilyn S., Cederbrant, Karin, Sandelin, Kerstin, Pontén, Ingrid, Bolcsfoldi, George, Ferguson, Lynnette R., Pearson, Amira, Majeska, Jenness B., Tarca, James P., Hynes, Geoffrey M., Lynch, Anthony M., McNamee, James P., Bellier, Pascale V., Parenteau, Monique, Blakey, David, Bayley, Janet, van der Leede, Bas-Jan M., Vanparys, Philippe, Harbach, Philip R., Zhao, Shuou, Filipunas, Anthony L., Johnson, Carol W., Tometsko, Carol R., Dertinger, Stephen D.

“…An interlaboratory study was performed to validate an anti‐CD71/flow cytometry‐based technique for enumerating micronucleated reticulocytes (MN‐RETs) in mouse…”
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Enumeration of micronucleated reticulocytes in rat peripheral blood: a flow cytometric study by Torous, Dorothea K, Dertinger, Stephen D, Hall, Nikki E, Tometsko, Carol R

“…Micronuclei (MN) are routinely enumerated in mouse peripheral blood to index genotoxicity. Recent data from the Collaborative Study Group for the Micronucleus…”
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Enumeration of micronucleated CD71-positive human reticulocytes with a single-laser flow cytometer by Dertinger, Stephen D., Torous, Dorothea K., Hall, Nikki E., Murante, Francis G., Gleason, Sarah E., Miller, Richard K., Tometsko, Carol R.

“…The extreme rarity of micronucleated reticulocytes (RETs) in the peripheral blood of non-splenectomized humans has precluded facile enumeration of these cells,…”
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Performance of flow cytometric analysis for the micronucleus assay—a reconstruction model using serial dilutions of malaria-infected cells with normal mouse peripheral blood by Torous, Dorothea, Asano, Norihide, Tometsko, Carol, Sugunan, Siva, Dertinger, Stephen, Morita, Takeshi, Hayashi, Makoto

“…To confirm the performance and statistical power of a flow cytometric method for scoring micronucleated erythrocytes, reconstruction experiments were…”
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Malaria-infected erythrocytes serve as biological standards to ensure reliable and consistent scoring of micronucleated erythrocytes by flow cytometry by Dertinger, Stephen D., Torous, Dorothea K., Hall, Nikki E., Tometsko, Carol R., Gasiewicz, Thomas A.

“…A procedure for optimizing the configuration of flow cytometers for enumerating micronucleated erythrocytes is described. The method is based on the use of a…”
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Flow cytometric enumeration of micronucleated reticulocytes: High transferability among 14 laboratories by Torous, Dorothea K., Hall, Nikki E., Dertinger, Stephen D., Diehl, Marilyn S., Illi-Love, Anne H., Cederbrant, Karin, Sandelin, Kerstin, Bolcsfoldi, George, Ferguson, Lynnette R., Pearson, Amira, Majeska, Jenness B., Tarca, James P., Hewish, Dean R., Doughty, Larissa, Fenech, Michael, Weaver, James L., Broud, Dennis D., Gatehouse, David G., Hynes, Geoffrey M., Kwanyuen, Puntipa, McLean, Jack, McNamee, James P., Parenteau, Monique, Van Hoof, Veerle, Vanparys, Philippe, Lenarczyk, Marek, Siennicka, Joanna, Litwinska, Bogumila, Slowikowska, Maria G., Harbach, Philip R., Johnson, Carol W., Zhao, Shuou, Aaron, Charles S., Lynch, Anthony M., Marshall, Ian C., Rodgers, Brenda, Tometsko, Carol R.

“…This laboratory previously described a single‐laser flow cytometric method, which effectively resolves micronucleated erythrocyte populations in rodent…”
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Measurement of cytogenetic damage in rodent blood with a single-laser flow cytometer by Dertinger, Stephen, Torous, Dorthea, Hall, Nikki, Tometsko, Carol

“…The in vivo rodent micronucleus test is widely utilized to screen chemicals for genotoxic activity. Double-strand chromosome breaks or dysfunction of the…”
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Interlaboratory validation of a CD71-based flow cytometric method (Microflow®) for the scoring of micronucleated reticulocytes in mouse peripheral blood: Interlaboratory Validation by Torous, Dorothea K., Hall, Nikki E., Illi-Love, Anne H., Diehl, Marilyn S., Cederbrant, Karin, Sandelin, Kerstin, Pontén, Ingrid, Bolcsfoldi, George, Ferguson, Lynnette R., Pearson, Amira, Majeska, Jenness B., Tarca, James P., Hynes, Geoffrey M., Lynch, Anthony M., McNamee, James P., Bellier, Pascale V., Parenteau, Monique, Blakey, David, Bayley, Janet, van der Leede, Bas-Jan M., Vanparys, Philippe, Harbach, Philip R., Zhao, Shuou, Filipunas, Anthony L., Johnson, Carol W., Tometsko, Carol R., Dertinger, Stephen D.

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An automated method for discriminating aneugen- vs. clastogen-induced micronuclei by Torous, Dorothea K., Dertinger, Stephen D., Hall, Nikki E., Tometsko, Carol R.

“…A flow cytometric (FCM) procedure for quantitating micronucleated reticulocytes in mouse peripheral blood samples was evaluated for its ability to discriminate…”
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Cross-species genetic toxicity assessment accomplished by flow cytometric analysis of blood by Bemis, Jeffrey C, Torous, Dorothea K, Tometsko, Carol R, Dertinger, Stephen D

“…The formation of micronuclei in blood cells has been an established indicator of genotoxicity for decades. Standard microscopy methods are time-consuming and…”
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Effects of photosensitive chemicals on malaria parasite cells by Tometsko, A M, Hare, J D, Tometsko, C R, Lam, P Y, Lipman, D

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