Search Results - "Tomasek, JJ"

Myofibroblasts and mechano-regulation of connective tissue remodelling by Gabbiani, Giulio, Chaponnier, Christine, Tomasek, James J, Hinz, Boris, Brown, Robert A

“…During the past 20 years, it has become generally accepted that the modulation of fibroblastic cells towards the myofibroblastic phenotype, with acquisition of…”
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Alpha-smooth muscle actin expression upregulates fibroblast contractile activity by Hinz, B, Celetta, G, Tomasek, J J, Gabbiani, G, Chaponnier, C

“…To evaluate whether alpha-smooth muscle actin (alpha-SMA) plays a role in fibroblast contractility, we first compared the contractile activity of rat…”
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Matrix metalloproteinase inhibitor GM 6001 attenuates keratinocyte migration, contraction and myofibroblast formation in skin wounds by Mirastschijski, Ursula, Haaksma, Carol J., Tomasek, James J., Ågren, Magnus S.

“…In this study, we examined the impact of matrix metalloproteinases (MMP) on epithelialization, granulation tissue development, wound contraction, and α-smooth…”
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Regulation of LPA-Promoted Myofibroblast Contraction: Role of Rho, Myosin Light Chain Kinase, and Myosin Light Chain Phosphatase by Parizi, Mojgan, Howard, Eric W., Tomasek, James J.

“…Myofibroblasts generate the contractile force responsible for wound healing and pathological tissue contracture. In this paper the stress-relaxed collagen…”
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Characterization of neuropathic bladder smooth muscle cells in culture by Lin, Hsueh-Kung, Cowan, Rick, Moore, Pete, Zhang, Yuanyuan, Yang, Qing, Peterson, Jr, John A, Tomasek, James J, Kropp, Bradley P, Cheng, Earl Y

“…Clinically bladder cells used in tissue engineering techniques will come from neuropathic bladders and not normal bladders. We determined if neuropathic…”
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Mechanical Properties of the Extracellular Matrix Influence Fibronectin Fibril Assembly in Vitro by Halliday, Nancy L., Tomasek, James J.

“…Mechanical properties of the extracellular matrix (ECM) are proposed to influence cell behavior and biological activity. The influence of the mechanical…”
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Deletion of smooth muscle α-actin alters blood-retina barrier permeability and retinal function by TOMASEK, James J, HAAKSMA, Carol J, SCHWARTZ, Robert J, VUONG, Duc T, ZHANG, Sarah X, ASH, John D, MA, Jian-Xing, AL-UBAIDI, Muayyad R

“…Vascular smooth muscle (SM) cells and pericytes are essential for normal vascular development. SM alpha-actin null mice were used to determine whether vascular…”
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Gelatinase A Activation Is Regulated by the Organization of the Polymerized Actin Cytoskeleton by Tomasek, James J., Halliday, Nancy L., Updike, Dawn L., Ahern-Moore, Joan S., Vu, Thien-Khai H., Liu, Rose W., Howard, Eric W.

“…Gelatinase A (GL-A) is a matrix metalloproteinase (MMP) involved in both connective tissue remodeling and tumor invasion. GL-A activation is mediated by a…”
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Decreased expression of smooth muscle alpha-actin results in decreased contractile function of the mouse bladder by Zimmerman, R A, Tomasek, J J, McRae, J, Haaksma, C J, Schwartz, R J, Lin, H K, Cowan, R L, Jones, A N, Kropp, B P

“…Smooth muscle alpha-actin (SMalphaA) is an important actin isoform for functional contractility in the mouse bladder. Alterations in the expression of SMalphaA…”
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Characterization of cultured bladder smooth muscle cells: assessment of in vitro contractility by Kropp, B P, Zhang, Y, Tomasek, J J, Cowan, R, Furness, 3rd, P D, Vaughan, M B, Parizi, M, Cheng, E Y

“…The contractile properties of in vitro cultured bladder smooth muscle cells (SMC) are unknown. This study characterized the in vitro contractile response of…”
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Identification and Cloning of the Membrane-associated Serine Protease, Hepsin, from Mouse Preimplantation Embryos by Vu, Thien-Khai H., Liu, Rose W., Haaksma, Carol J., Tomasek, James J., Howard, Eric W.

“…Previous studies have suggested the existence of a membrane-associated serine protease expressed by mammalian preimplantation embryos. In this study, we have…”
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Cellular structure and biology of Dupuytren's disease by Tomasek, J J, Vaughan, M B, Haaksma, C J

“…Numerous studies support the idea that the myofibroblast is a key cell responsible for the tissue contraction in Dupuytren's disease. In vitro models have been…”
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Cellular Contraction of Collagen Lattices Is Inhibited by Nonenzymatic Glycation by Howard, Eric W., Benton, Richard, Ahern-Moore, Joan, Tomasek, James J.

“…High glucose concentrations associated with diabetes have been shown to cause the nonenzymatic modification of proteins. Reducing sugars covalently bind to…”
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Correlation of alpha-smooth muscle actin expression and contraction in Dupuytren's disease fibroblasts by Tomasek, J, Rayan, G M

“…We studied 11 nodules from patients with Dupuytren's contracture to determine whether alpha-smooth muscle actin expression in Dupuytren's fibroblasts is…”
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Cytosolic Delivery and Characterization of the TcdB Glucosylating Domain by Using a Heterologous Protein Fusion by SPYRES, Lea. M, MAEN QA'DAN, MEADER, Amy, TOMASEK, James J, HOWARD, Eric W, BALLARD, Jimmy D

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Pharmacologic regulation of Dupuytren's fibroblast contraction in vitro by Rayan, G M, Parizi, M, Tomasek, J J

“…Dupuytren's disease is associated with contraction of specialized fibroblasts present in the diseased palmar fascia. Pharmacologic agents were evaluated for…”
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Internalized Plasma Membrane Cholesterol Passes through an Endosome Compartment That Is Distinct from the Acid Vesicle–Lysosome Compartment by Porpaczy, Zoltan, Tomasek, James J., Freeman, Dale A.

“…Cholesterol from the plasma membrane of MA-10 Leydig tumor cells is internalized into the cell and either esterified or used as substrate for steroid hormone…”
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Evidence for the nonmuscle nature of the "myofibroblast" of granulation tissue and hypertropic scar. An immunofluorescence study by Eddy, RJ, Petro, JA, Tomasek, JJ

“…Contraction is an important phenomenon in wound repair and hypertrophic scarring. Studies indicate that wound contraction involves a specialized cell known as…”
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Diabetic and age-related enhancement of collagen-linked fluorescence in cortical bones of rats by Tomasek, J J, Meyers, S W, Basinger, J B, Green, D T, Shew, R L

“…Nonenzymatic collagen cross-linking occurs in a variety of connective tissues as a result of formation of advanced glycosylation end products. Diabetes and…”
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Thrombin stimulates fibroblast-mediated collagen lattice contraction by its proteolytically activated receptor by Pilcher, B K, Kim, D W, Carney, D H, Tomasek, J J

“…Fibroblast contraction is proposed to play an important role in tissue contraction during events such as wound healing. Thrombin has been implicated to promote…”
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