Search Results - "Tomanelli, Michele"
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Domestic Animal Models of Central Nervous System Tumors: Focus on Meningiomas
Published in Life (Basel, Switzerland) (30-11-2023)“…Intracranial primary tumors (IPTs) are aggressive forms of malignancies that cause high mortality in both humans and domestic animals. Meningiomas are frequent…”
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LKB1 Deficiency Renders NSCLC Cells Sensitive to ERK Inhibitors
Published in Journal of thoracic oncology (01-03-2020)“…Serine/threonine kinase 11 (LKB1/STK11) is one of the most mutated genes in NSCLC accounting for approximately one-third of cases and its activity is impaired…”
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Wee1 inhibitor MK1775 sensitizes KRAS mutated NSCLC cells to sorafenib
Published in Scientific reports (17-01-2018)“…Non-Small-Cell Lung Cancer (NSCLC) is a poorly chemosensitive tumor and targeted therapies are only used for about 15% of patients where a specific driving and…”
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Abstract 147: Identification of cell sub-populations in Neuroblastoma cell lines with single-cell-sequencing analysis
Published in Cancer research (Chicago, Ill.) (22-03-2024)“…Abstract Neuroblastoma is the most frequent extracranial tumor in neonatal patients. Engineering SKNBE2 Myc-N amplified Neuroblastoma cell lines we generated…”
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