Search Results - "Tomanek, R. J."

Bradycardia-Induced Coronary Angiogenesis Is Dependent on Vascular Endothelial Growth Factor by Zheng, Wei, Brown, Margaret D, Brock, Tommy A, Bjercke, Robert J, Tomanek, Robert J

“…A marked coronary angiogenesis is known to occur with chronic bradycardia. We tested the hypothesis that vascular endothelial growth factor (VEGF), an…”
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Early Coronary Angiogenesis in Response to Thyroxine: Growth Characteristics and Upregulation of Basic Fibroblast Growth Factor by Tomanek, Robert J, Doty, Matthew K, Sandra, Alexander

“…Although a substantial coronary angiogenesis occurs after thyroid hormone treatment, its regulation and relationship to cardiac hypertrophy are not understood…”
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Cellular and Ventricular Contractile Dysfunction in Experimental Canine Mitral Regurgitation by Urabe, Yoshitoshi, Mann, Douglas L, Kent, Robert L, Nakano, Kiyoharu, Tomanek, Robert J, Carabello, Blase A, IV, George Cooper

“…This study was designed to answer two questions. First, does the left ventricular contractile dysfunction resulting from mitral regurgitation (MR) reflect a…”
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Response of the coronary vasculature to myocardial hypertrophy by Tomanek, Robert J.

“…Cardiac hypertrophy is often characterized by abnormalities in myocardial perfusion, including decreased coronary reserve, increased minimal coronary vascular…”
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Rate of coronary vascularization during embryonic chicken development is influenced by the rate of myocardial growth by TOMANEK, R. J, HU, N, PHAN, B, CLARK, E. B

“…We tested the hypothesis that the degree of coronary microvessel formation in the embryonic heart is regulated by the magnitude of myocardial growth. The…”
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Morphometry of Canine Coronary Arteries, Arterioles, and Capillaries during Hypertension and Left Ventricular Hypertrophy by Tomanek, Robert J, Palmer, Pat J, Peiffer, Gina L, Schreiber, Kathy L, Eastham, Charles L, Marcus, Melvin L

“…The mechanisms responsible for the increase in minimal coronary vascular resistance per unit mass of myocardium in animals with chronic hypertension and left…”
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Effect of increased pressure on ventricular growth in stage 21 chick embryos by Clark, E B, Hu, N, Frommelt, P, Vandekieft, G K, Dummett, J L, Tomanek, R J

“…We studied the effect of increased ventricular pressure on heart growth in the stage 21 (3.5-day) chick embryo. Ventricular pressure was increased by…”
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Proportional arteriolar growth accompanies cardiac hypertrophy induced by volume overload by Chen, Y, Torry, R J, Baumbach, G L, Tomanek, R J

“…Volume overload-induced cardiac hypertrophy is characterized by normal coronary reserve and maximal flow. Accordingly, we tested the hypothesis that both…”
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Age as a modulator of coronary capillary angiogenesis by TOMANEK, R. J

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Compensated coronary microvascular growth in senescent rats with thyroxine-induced cardiac hypertrophy by Tomanek, R J, Connell, P M, Butters, C A, Torry, R J

“…We tested the hypothesis that coronary angiogenesis in response to chronic thyroxine (T4) treatment is not limited by age. Male Fischer 344 rats aged either 8…”
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Role of lowering arterial pressure on maximal coronary flow with and without regression of cardiac hypertrophy by Canby, C A, Tomanek, R J

“…This study was initiated to test the hypothesis that attenuation of long-term hypertension with or without regression of left ventricular hypertrophy (LVH)…”
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Coronary Angiogenesis During Long-term Hypertension and Left Ventricular Hypertrophy in Dogs by Tomanek, Robert J, Schalk, Kimberly A, Marcus, Melvin L, Harrison, David G

“…Many studies have documented that during the development of left ventricular hypertrophy (LVH) coronary vascular growth lags behind that of cardiac muscle. To…”
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Hypertrophic response to hemodynamic overload: role of load vs. renin-angiotensin system activation by Koide, M., Carabello, B. A., Conrad, C. C., Buckley, J. M., DeFreyte, G., Barnes, M., Tomanek, R. J., Wei, C. C., Dell'Italia, L. J., Cooper, G. 4th, Zile, M. R.

“…Myocardial hypertrophy is one of the basic mechanisms by which the heart compensates for hemodynamic overload. The mechanisms by which hemodynamic overload is…”
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L-cysteine selectively potentiates nitroglycerin-induced dilation of small coronary microvessels by Sellke, F W, Tomanek, R J, Harrison, D G

“…Nitroglycerin potently dilates large coronary arteries but has minimal effect on coronary resistance vessels. Thus, nitroglycerin is not likely to be converted…”
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Myocardial capillarity and maximal capillary diffusion capacity in exercise-trained dogs by Laughlin, M H, Tomanek, R J

“…Our purpose was to determine whether changes in myocardial capillarity underlie the exercise training-induced increases in coronary transport capacity…”
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Capillary growth and geometry during long-term hypertension and myocardial hypertrophy in dogs by Tomanek, R J, Wessel, T J, Harrison, D G

“…Angiogenic response of the myocardial capillary bed to long-term (7 mo) renovascular hypertension (one-kidney, one-clip) was assessed in eight mongrel dogs and…”
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Mechanisms of coronary angiogenesis in response to stretch: role of VEGF and TGF-beta by Zheng, W, Seftor, E A, Meininger, C J, Hendrix, M J, Tomanek, R J

“…To test the hypotheses that cyclic stretch of 1) cardiac myocytes produces factors that trigger angiogenic events in coronary microvascular endothelial cells…”
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Dipyridamole-induced capillary growth in normal and hypertrophic hearts by Torry, R J, O'Brien, D M, Connell, P M, Tomanek, R J

“…Chronic increases in myocardial blood flow have been shown to stimulate capillary proliferation in normal growing hearts. It is unknown, however, if elevated…”
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Late onset renal hypertension in old rats alters left ventricular structure and function by Tomanek, R J, Aydelotte, M R

“…This study was designed to test the hypothesis that the left ventricle of the senescent rat has a limited compensatory response to late onset hypertension…”
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Alterations in the coronary circulation in hypertrophied ventricles by Marcus, M L, Harrison, D G, Chilian, W M, Koyanagi, S, Inou, T, Tomanek, R J, Martins, J B, Eastham, C L, Hiratzka, L F

“…During the past decade our understanding of the complex interaction between cardiac muscle and coronary vascular growth has increased substantially. Some types…”
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