Search Results - "Tomaipitinca, Luana"
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Multifaceted Roles of GSK-3 in Cancer and Autophagy-Related Diseases
Published in Oxidative medicine and cellular longevity (01-01-2017)“…GSK-3 is a ubiquitously expressed serine/threonine kinase existing as GSK-3α and GSK-3β isoforms, both active under basal conditions and inactivated upon…”
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NK Cell Anti-Tumor Surveillance in a Myeloid Cell-Shaped Environment
Published in Frontiers in immunology (17-12-2021)“…NK cells are innate lymphoid cells endowed with cytotoxic capacity that play key roles in the immune surveillance of tumors. Increasing evidence indicates that…”
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c-FLIP regulates autophagy by interacting with Beclin-1 and influencing its stability
Published in Cell death & disease (08-07-2021)“…c-FLIP (cellular FLICE-like inhibitory protein) protein is mostly known as an apoptosis modulator. However, increasing data underline that c-FLIP plays…”
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Anti-tumor Effect of Oleic Acid in Hepatocellular Carcinoma Cell Lines via Autophagy Reduction
Published in Frontiers in cell and developmental biology (05-02-2021)“…Oleic acid (OA) is a component of the olive oil. Beneficial health effects of olive oil are well-known, such as protection against liver steatosis and against…”
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Lipid Storage and Autophagy in Melanoma Cancer Cells
Published in International journal of molecular sciences (15-06-2017)“…Cancer stem cells (CSC) represent a key cellular subpopulation controlling biological features such as cancer progression in all cancer types. By using…”
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The Role of Autophagy in Liver Epithelial Cells and Its Impact on Systemic Homeostasis
Published in Nutrients (11-04-2019)“…Autophagy plays a role in several physiological and pathological processes as it controls the turnover rate of cellular components and influences cellular…”
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Impact on NK cell functions of acute versus chronic exposure to extracellular vesicle‐associated MICA: Dual role in cancer immunosurveillance
Published in Journal of extracellular vesicles (01-01-2022)“…Natural killer (NK) cells are innate cytotoxic lymphocytes that play a key role in cancer immunosurveillance thanks to their ability to recognize and kill…”
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A novel role of c-FLIP protein in regulation of ER stress response
Published in Cellular signalling (01-09-2016)“…Cellular-Flice-like inhibitory protein (c-FLIP) is an apoptosis modulator known to inhibit the extrinsic apoptotic pathway thus blocking Caspase-8 processing…”
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NK cell surveillance of hematological malignancies. Therapeutic implications and regulation by chemokine receptors
Published in Molecular aspects of medicine (01-08-2021)“…NK cells are circulating innate lymphoid cells that constantly move from bloodstream into tissues, exerting several functions including tumor surveillance. For…”
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Granzyme A and CD160 expression delineates ILC1 with graded functions in the mouse liver
Published in European journal of immunology (01-11-2021)“…Type 1 innate lymphoid cells (ILC1) are tissue‐resident lymphocytes that provide early protection against bacterial and viral infections. Discrete…”
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Expression of Genes Related to Lipid Handling and the Obesity Paradox in Melanoma: Database Analysis
Published in JMIR cancer (19-05-2020)“…Publicly available genomic and transcriptomic data in searchable databases allow researchers to investigate specific medical issues in thousands of patients…”
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Skin mesenchymal niches maintain and protect AML-initiating stem cells
Published in The Journal of experimental medicine (02-10-2023)“…Leukemia cutis or leukemic cell infiltration in skin is one of the common extramedullary manifestations of acute myeloid leukemia (AML) and signifies a poorer…”
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