Search Results - "Tolvanen, Tuula"

Human brown adipose tissue [15O]O2 PET imaging in the presence and absence of cold stimulus by u Din, Mueez, Raiko, Juho, Saari, Teemu, Kudomi, Nobu, Tolvanen, Tuula, Oikonen, Vesa, Teuho, Jarmo, Sipilä, Hannu T, Savisto, Nina, Parkkola, Riitta, Nuutila, Pirjo, Virtanen, Kirsi A.

“…Purpose Brown adipose tissue (BAT) is considered a potential target for combatting obesity, as it produces heat instead of ATP in cellular respiration due to…”
Get full text

The Effects of Bariatric Surgery on Pancreatic Lipid Metabolism and Blood Flow by Honka, Henri, Koffert, Jukka, Hannukainen, Jarna C, Tuulari, Jetro J, Karlsson, Henry K, Immonen, Heidi, Oikonen, Vesa, Tolvanen, Tuula, Soinio, Minna, Salminen, Paulina, Kudomi, Nobu, Mari, Andrea, Iozzo, Patricia, Nuutila, Pirjo

“…Context: Bariatric surgery leads to a rapid and sustained weight loss often accompanied with improvement in glucose homeostasis. Objective: The objective of…”
Get full text

Assessment of a digital and an analog PET/CT system for accurate myocardial perfusion imaging with a flow phantom by Siekkinen, Reetta, Kirjavainen, Anna K., Koskensalo, Kalle, Smith, Nadia A.S., Fenwick, Andrew, Saunavaara, Virva, Tolvanen, Tuula, Iida, Hidehiro, Saraste, Antti, Teräs, Mika, Teuho, Jarmo

“…In Myocardial Perfusion Imaging (MPI) with Positron Emission Tomography/Computed Tomography (PET/CT) systems, accurate quantification is essential. We assessed…”
Get full text

Assessment of myocardial viability with [15O]water PET: A validation study in experimental myocardial infarction by Grönman, Maria, Tarkia, Miikka, Stark, Christoffer, Vähäsilta, Tommi, Kiviniemi, Tuomas, Lubberink, Mark, Halonen, Paavo, Kuivanen, Antti, Saunavaara, Virva, Tolvanen, Tuula, Teuho, Jarmo, Teräs, Mika, Savunen, Timo, Pietilä, Mikko, Ylä-Herttuala, Seppo, Roivainen, Anne, Knuuti, Juhani, Saraste, Antti

“…Assessment of myocardial viability is often needed in patients with chest pain and reduced ejection fraction. We evaluated the performance of reduced resting…”
Get full text

Radiosynthesis and preclinical evaluation of [68Ga]Ga-NOTA-folate for PET imaging of folate receptor β-positive macrophages by Moisio, Olli, Palani, Senthil, Virta, Jenni, Elo, Petri, Liljenbäck, Heidi, Tolvanen, Tuula, Käkelä, Meeri, Miner, Maxwell G., Herre, Erika Atencio, Marjamäki, Päivi, Örd, Tiit, Heinäniemi, Merja, Kaikkonen, Minna U., Zhang, Fenghua, Srinivasarao, Madduri, Knuuti, Juhani, Low, Philip S., Saraste, Antti, Li, Xiang-Guo, Roivainen, Anne

“…Folate receptor β (FR-β), a marker expressed on macrophages, is a promising target for imaging of inflammation. Here, we report the radiosynthesis and…”
Get full text

Preliminary protocol for measuring the reproducibility and accuracy of flow values on digital PET/CT systems in [15O]H2O myocardial perfusion imaging using a flow phantom by Siekkinen, Reetta, Partanen, Heidi, Kukola, Linda, Tolvanen, Tuula, Fenwick, Andrew, Smith, Nadia A. S., Teräs, Mika, Saraste, Antti, Teuho, Jarmo

“…Background Several factors may decrease the accuracy of quantitative PET myocardial perfusion imaging (MPI). It is therefore essential to ensure that…”
Get full text

Imaging of αvβ3 integrin expression in experimental myocardial ischemia with [68Ga]NODAGA-RGD positron emission tomography by Grönman, Maria, Tarkia, Miikka, Kiviniemi, Tuomas, Halonen, Paavo, Kuivanen, Antti, Savunen, Timo, Tolvanen, Tuula, Teuho, Jarmo, Käkelä, Meeri, Metsälä, Olli, Pietilä, Mikko, Saukko, Pekka, Ylä-Herttuala, Seppo, Knuuti, Juhani, Roivainen, Anne, Saraste, Antti

“…BACKGROUNDRadiolabeled RGD peptides detect αvβ3 integrin expression associated with angiogenesis and extracellular matrix remodeling after myocardial…”
Get full text

Myocardial perfusion reserve of kidney transplant patients is well preserved by Päivärinta, Johanna, Metsärinne, Kaj, Löyttyniemi, Eliisa, Teuho, Jarmo, Tolvanen, Tuula, Knuuti, Juhani, Koivuviita, Niina

“…Background Chronic kidney disease (CKD) is associated with endothelial dysfunction and increased cardiovascular mortality. Endothelial dysfunction can be…”
Get full text

64Cu- and 68Ga-Labelled [Nle14,Lys40(Ahx-NODAGA)NH2]-Exendin-4 for Pancreatic Beta Cell Imaging in Rats by Kirsi, Mikkola, Cheng-Bin, Yim, Veronica, Fagerholm, Tamiko, Ishizu, Viki-Veikko, Elomaa, Johan, Rajander, Jori, Jurttila, Tiina, Saanijoki, Tuula, Tolvanen, Marko, Tirri, Eleni, Gourni, Martin, Béhé, Martin, Gotthardt, Claude, Reubi Jean, Helmut, Mäcke, Anne, Roivainen, Olof, Solin, Pirjo, Nuutila

“…Purpose Glucagon-like peptide-1 receptor (GLP-1R) is a molecular target for imaging of pancreatic beta cells. We compared the ability of [Nle 14 ,Lys 40…”
Get full text

Change in brain amyloid load and cognition in patients with amnestic mild cognitive impairment: a 3-year follow-up study by Rauhala, Elina, Johansson, Jarkko, Karrasch, Mira, Eskola, Olli, Tolvanen, Tuula, Parkkola, Riitta, Virtanen, Kirsi A., Rinne, Juha O.

“…Background Our aim was to investigate the discriminative value of 18 F-Flutemetamol PET in longitudinal assessment of amyloid beta accumulation in amnestic…”
Get full text

Effect of Attenuation Correction on Regional Quantification Between PET/MR and PET/CT: A Multicenter Study Using a 3-Dimensional Brain Phantom by Teuho, Jarmo, Johansson, Jarkko, Linden, Jani, Hansen, Adam Espe, Holm, Søren, Keller, Sune H, Delso, Gaspar, Veit-Haibach, Patrick, Magota, Keiichi, Saunavaara, Virva, Tolvanen, Tuula, Teräs, Mika, Iida, Hidehiro

“…A spatial bias in brain PET/MR exists compared with PET/CT, because of MR-based attenuation correction. We performed an evaluation among 4 institutions, 3…”
Get full text

Renal vascular resistance is increased in patients with kidney transplant by Päivärinta, Johanna, Oikonen, Vesa, Räisänen-Sokolowski, Anne, Tolvanen, Tuula, Löyttyniemi, Eliisa, Iida, Hidehiro, Nuutila, Pirjo, Metsärinne, Kaj, Koivuviita, Niina

“…Despite improvement in short-term outcome of kidney transplants, the long-term survival of kidney transplants has not changed over past decades. Kidney biopsy…”
Get full text

Biodistribution and radiation dosimetry of [11C]choline: a comparison between rat and human data by Tolvanen, Tuula, Yli-Kerttula, Timo, Ujula, Tiina, Autio, Anu, Lehikoinen, Pertti, Minn, Heikki, Roivainen, Anne

“…Purpose Methyl- 11 C-choline ([ 11 C]choline) is a radiopharmaceutical used for oncological PET studies. We investigated the biodistribution and biokinetics of…”
Get full text

Low kidney uptake of GLP-1R-targeting, beta cell-specific PET tracer, 18F-labeled [Nle14,Lys40]exendin-4 analog, shows promise for clinical imaging by Mikkola, Kirsi, Yim, Cheng-Bin, Lehtiniemi, Paula, Kauhanen, Saila, Tarkia, Miikka, Tolvanen, Tuula, Nuutila, Pirjo, Solin, Olof

“…Background Several radiometal-labeled, exendin-based tracers that target glucagon-like peptide-1 receptors (GLP-1R) have been intensively explored for β cell…”
Get full text

[18F]FDG Accumulation in Early Coronary Atherosclerotic Lesions in Pigs by Tarkia, Miikka, Saraste, Antti, Stark, Christoffer, Vähäsilta, Tommi, Savunen, Timo, Strandberg, Marjatta, Saunavaara, Virva, Tolvanen, Tuula, Teuho, Jarmo, Teräs, Mika, Metsälä, Olli, Rinne, Petteri, Heinonen, Ilkka, Savisto, Nina, Pietilä, Mikko, Saukko, Pekka, Roivainen, Anne, Knuuti, Juhani

“…Inflammation is an important contributor to atherosclerosis progression. A glucose analogue 18F-fluorodeoxyglucose ([18F]FDG) has been used to detect…”
Get full text

Human radiation dosimetry of [11C]MeAIB, a new tracer for imaging of system A amino acid transport by Tolvanen, Tuula, Någren, Kjell, Yu, Meixiang, Sutinen, Eija, Havu-Aurén, Katja, Jyrkkiö, Sirkku, Asola, Markku, Kotoneva, Eira, Nuutila, Pirjo, Minn, Heikki

“…[N-methyl-11C]alpha-methylaminoisobutyric acid ([11C]MeAIB) is a promising positron emission tomography (PET) tracer for imaging hormonally regulated system A…”
Get full text

Safety, Biodistribution, and Radiation Dosimetry of 18F-rhPSMA-7.3 in Healthy Adult Volunteers by Tolvanen, Tuula, Kalliokoski, Kari, Malaspina, Simona, Kuisma, Anna, Lahdenpohja, Salla, Postema, Ernst J, Miller, Matthew P, Scheinin, Mika

“…This first-in-humans study investigated the safety, biodistribution, and radiation dosimetry of a novel 18F-labeled radiohybrid prostate-specific membrane…”
Get full text

Small animal PET with spontaneous inhalation of 15 O-labelled oxygen gases: Longitudinal assessment of cerebral oxygen metabolism in a rat model of neonatal hypoxic-ischaemic encephalopathy by Shimochi, Saeka, Ihalainen, Jukka, Parikka, Vilhelmiina, Kudomi, Nobuyuki, Tolvanen, Tuula, Hietanen, Ari, Kokkomäki, Esa, Johansson, Stefan, Tsuji, Masahiro, Kanaya, Shigehiko, Yatkin, Emrah, Grönroos, Tove J, Iida, Hidehiro

“…Perinatal hypoxic-ischaemic encephalopathy (HIE) is the leading cause of irreversible brain damage resulting in serious neurological dysfunction among…”
Get full text

Flare on [18F]PSMA-1007 PET/CT after short-term androgen deprivation therapy and its correlation to FDG uptake: possible marker of tumor aggressiveness in treatment-naïve metastatic prostate cancer patients by Malaspina, Simona, Ettala, Otto, Tolvanen, Tuula, Rajander, Johan, Eskola, Olli, Boström, Peter. J., Kemppainen, Jukka

“…Purpose Short-term androgen deprivation therapy (ADT) is known to increase heterogeneously prostate-specific membrane antigen (PSMA) expression. This…”
Get full text

1-11C-Methyl-4-Piperidinyl-N-Butyrate Radiation Dosimetry in Humans by Dynamic Organ-Specific Evaluation by Virta, Jere R, Tolvanen, Tuula, Nagren, Kjell, Bruck, Anna, Roivainen, Anne, Rinne, Juha O

Get full text