Search Results - "Toloue, M M"

Stable heteroplasmy at the single-cell level is facilitated by intercellular exchange of mtDNA by Jayaprakash, Anitha D, Benson, Erica K, Gone, Swapna, Liang, Raymond, Shim, Jaehee, Lambertini, Luca, Toloue, Masoud M, Wigler, Mike, Aaronson, Stuart A, Sachidanandam, Ravi

“…Eukaryotic cells carry two genomes, nuclear (nDNA) and mitochondrial (mtDNA), which are ostensibly decoupled in their replication, segregation and inheritance…”
Get full text

IGF2BP3 Modulates the Interaction of Invasion-Associated Transcripts with RISC by Ennajdaoui, Hanane, Howard, Jonathan M., Sterne-Weiler, Timothy, Jahanbani, Fereshteh, Coyne, Doyle J., Uren, Philip J., Dargyte, Marija, Katzman, Sol, Draper, Jolene M., Wallace, Andrew, Cazarez, Oscar, Burns, Suzanne C., Qiao, Mei, Hinck, Lindsay, Smith, Andrew D., Toloue, Masoud M., Blencowe, Benjamin J., Penalva, Luiz O.F., Sanford, Jeremy R.

“…Insulin-like growth factor 2 mRNA binding protein 3 (IGF2BP3) expression correlates with malignancy, but its role(s) in pathogenesis remains enigmatic. We…”
Get full text

Asymmetric Configurations and N-terminal Rearrangements in Connexin26 Gap Junction Channels by Oshima, Atsunori, Tani, Kazutoshi, Toloue, Masoud M., Hiroaki, Yoko, Smock, Amy, Inukai, Sayaka, Cone, Angela, Nicholson, Bruce J., Sosinsky, Gina E., Fujiyoshi, Yoshinori

“…Gap junction channels are unique in that they possess multiple mechanisms for channel closure, several of which involve the N terminus as a key component in…”
Get full text

Can We Use Blood Biomarkers as Entry Criteria and for Monitoring Drug Treatment Effects in Clinical Trials? A Report from the EU/US CTAD Task Force by Angioni, D., Hansson, O., Bateman, R. J., Rabe, C., Toloue, M., Braunstein, J. B., Agus, S., Sims, J. R., Bittner, T., Carrillo, M. C., Fillit, H., Masters, C. L., Salloway, S., Aisen, P., Weiner, M., Vellas, B., Gauthier, S., Abushakra, Susan, Afshar, Mohammad, Alam, John, Algeciras-Schimnich, Alicia, Andrieu, Sandrine, Ballard, Clive, Baruch, Amos, Batrla, Richard, Baudler, Monika, Bell, Joanne, Bozeat, Sasha, Brooks, Dawn, Brooks, Tricia, Bullain, Szofia, Burmeister, Jan, Cho, Min, Collins, Emily, Cook, Gavin, Cummings, Jeffrey, Dague, Chris, De Santi, Susan, Doody, Rachelle, Dunn, Billy, Egan, Michael, Eriksson, Sven, Esquivel, Rianne, Fagan, Tom, Ferrell, Phyllis, Gallagher, Michela, Grönblad, Anna-Kaija, Hains, Avis, Hampel, Harald, Hefting, Nanco, Hendrix, Suzanne, Ho, Carole, Hu, Helen, Ismail, Zahinoor, Jones, Daryl, Kinney, Gene, Kinnon, Paul, Kurzman, Ricky, Lannfelt, Lars, Lawson, John, LeBastard, Nathalie, Lewandowski, Nicole, Lim, Carine, Lyketsos, Costantine, Masterman, Donna, Lu, Ming, Mintun, Mark, Molinuevo, José Luis, Monteiro, Cecilia, Navia, Bradford, Odergren, Tomas, Osswald, Gunilla, Penny, Lewis, Pontecorvo, Michael, Porsteinsson, Anton, Raman, Rema, Respondek, Gesine, Reyderman, Larisa, Rogers, Sharon, Rosenberg, Paul, Rosenzweig-Lipson, Sharon, Roskey, Mark, Saad, Ziad, Schindler, Rachel, Selkoe, Dennis, Shulman, Melanie, Sink, Kaycee, Sipe, Lisa, Skovronsky, Daniel, Somers, Elizabeth, Soto, Maria, Streffer, Johannes, Such, Pedro, Suhy, Joyce, Touchon, Jacques, Vandijck, Manu, White, Anne, Wilson, David, Zago, Wagner, Zhou, Jin

“…In randomized clinical trials (RCTs) for Alzheimer’s Disease (AD), cerebrospinal fluid (CSF) and positron emission tomography (PET) biomarkers are currently…”
Get full text

Mutation of a Conserved Threonine in the Third Transmembrane Helix of α- and β-Connexins Creates a Dominant-negative Closed Gap Junction Channel by Beahm, Derek L., Oshima, Atsunori, Gaietta, Guido M., Hand, Galen M., Smock, Amy E., Zucker, Shoshanna N., Toloue, Masoud M., Chandrasekhar, Anjana, Nicholson, Bruce J., Sosinsky, Gina E.

“…Single site mutations in connexins have provided insights about the influence specific amino acids have on gap junction synthesis, assembly, trafficking, and…”
Get full text

Delivery of RNAi mediators by Ford, Lance P., Toloue, Masoud M.

“…Delivering polynucleotides into animals has been a major challenge facing their success as therapeutic agents. Given the matured understanding of…”
Get full text

A Clinical and Histomorphometric Study of Calcium Sulfate Compared With Freeze‐Dried Bone Allograft for Alveolar Ridge Preservation by Toloue, Samira M., Chesnoiu‐Matei, Ioana, Blanchard, Steven B.

“…Background: Many materials have been found to be effective in ridge preservation. The purpose of this study is to determine whether calcium sulfate (CS) is as…”
Get full text

Site-directed mutagenesis reveals putative regions of protein interaction within the transmembrane domains of connexins by Toloue, M M, Woolwine, Y, Karcz, J A, Kasperek, E M, Nicholson, B J, Skerrett, I M

“…Through cysteine-scanning mutagenesis, the authors have compared sites within the transmembrane domains of two connexins, one from the alpha-class (Cx50) and…”
Get more information

Connexin mutation that causes dominant congenital cataracts inhibits gap junctions, but not hemichannels, in a dominant negative manner by Banks, Eric A, Toloue, Masoud M, Shi, Qian, Zhou, Zifei Jade, Liu, Jialu, Nicholson, Bruce J, Jiang, Jean X

“…The connexin (Cx) 50, E48K, mutation is associated with a human dominant congenital cataract; however, the underlying molecular mechanism has not been…”
Get full text

14. A FULLY AUTOMATED INSTRUMENT FOR PREIMPLANTATION GENETIC TESTING (PGT-A) LIBRARY PREPARATION by Schneider, L., Cui, F., Brodsky, A., Fraser, M., Toloue, M., Tripathi, A.

“…Technology used in preimplantation genetic testing for aneuploidy (PGT-A) has rapidly evolved since its introduction in 1990. The most commonly used methods…”
Get full text

(4-Hydroxypyridine-2,6-dicarboxylato)oxovanadate(V)—a new insulin-like compound: chemistry, effects on myoblast and yeast cell growth and effects on hyperglycemia in rats with STZ-induced diabetes by Crans, Debbie C., Yang, Luqin, Alfano, Josephine A., Chi, Lai-Har, Jin, Wenzheng, Mahroof-Tahir, Mohammad, Robbins, Karen, Toloue, Masoud M., Chan, Leong K., Plante, Andrew J., Grayson, Rebecca Z., Willsky, Gail R.

“…A new insulin mimetic vanadium(V) complex is introduced: (4-hydroxypyridine-2,6-dicarboxylato)oxovanadate(V). The compound was designed based on the desire to…”
Get full text

Antibody targeted siRNA delivery by Toloue, Masoud M, Ford, Lance P

“…It is very clear that RNA interference (RNAi) is a potent and versatile tool for gene silencing. One of the hurdles to making siRNA/miRNA a human therapeutic…”
Get more information

Mutation of a Conserved Threonine in the Third Transmembrane Helix of α- and β-Connexins Creates a Dominant-negative Closed Gap Junction Channel by Derek L. Beahm, Atsunori Oshima, Guido M. Gaietta, Galen M. Hand, Amy E. Smock, Shoshanna N. Zucker, Masoud M. Toloue, Anjana Chandrasekhar, Bruce J. Nicholson, Gina E. Sosinsky

“…Single site mutations in connexins have provided insights about the influence specific amino acids have on gap junction synthesis, assembly, trafficking, and…”
Get full text

Structural And Functional Significance Of The N-terminus Of Cx26 Gap Junction Channels by Oshima, Atsunori, Tani, Kazutoshi, Toloue, Masoud M., Hiroaki, Yoko, Smock, Amy, Nicholson, Bruce J., Sosinsky, Gina E., Fujiyoshi, Yoshinori

Get full text

Structures of Connexin26 Mutants Demonstrate a Global Flexibility of Subunits and N-Terminal Rearrangements in the Pore by Oshima, Atsunori, Tani, Kazutoshi, Toloue, Masoud M., Hiroaki, Yoko, Smock, Amy, Inukai, Sayaka, Bruce, Nicholson J., Sosinsky, Gina E., Fujiyoshi, Yoshinori

Get full text

Mutation of a Conserved Threonine in the Third Transmembrane Helix of [alpha]- and [beta]-Connexins Creates a Dominant-negative Closed Gap Junction Channel by Beahm, Derek L, Oshima, Atsunori, Gaietta, Guido M, Hand, Galen M, Smock, Amy E, Zucker, Shoshanna N, Toloue, Masoud M, Chandrasekhar, Anjana, Nicholson, Bruce J, Sosinsky, Gina E

“…Single site mutations in connexins have provided insights about the influence specific amino acids have on gap junction synthesis, assembly, trafficking, and…”
Get full text