Search Results - "Tolonen, T."

Ecological drivers of multiple facets of beta diversity in a lentic macroinvertebrate metacommunity by Heino, Jani, Tolonen, Kimmo T.

“…Community ecology has broadened considerably with the recognition that it is not only at the species-level data where biological patterns and their…”
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Single-cell ATAC and RNA sequencing reveal pre-existing and persistent cells associated with prostate cancer relapse by Taavitsainen, S., Engedal, N., Cao, S., Handle, F., Erickson, A., Prekovic, S., Wetterskog, D., Tolonen, T., Vuorinen, E. M., Kiviaho, A., Nätkin, R., Häkkinen, T., Devlies, W., Henttinen, S., Kaarijärvi, R., Lahnalampi, M., Kaljunen, H., Nowakowska, K., Syvälä, H., Bläuer, M., Cremaschi, P., Claessens, F., Visakorpi, T., Tammela, T. L. J., Murtola, T., Granberg, K. J., Lamb, A. D., Ketola, K., Mills, I. G., Attard, G., Wang, W., Nykter, M., Urbanucci, A.

“…Prostate cancer is heterogeneous and patients would benefit from methods that stratify those who are likely to respond to systemic therapy. Here, we employ…”
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Local environment and space drive multiple facets of stream macroinvertebrate beta diversity by Rocha, Mariana Perez, Bini, Luis M., Domisch, Sami, Tolonen, Kimmo T., Jyrkänkallio-Mikkola, Jenny, Soininen, Janne, Hjort, Jan, Heino, Jani

“…Aim Understanding variation in biodiversity typically requires consideration of factors operating at different spatial scales. Recently, ecologists and…”
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Treatment of keloid scars with intralesional triamcinolone and 5-fluorouracil injections – a randomized controlled trial by Hietanen, KE, Järvinen, TA, Huhtala, H, Tolonen, TT, Kuokkanen, HO, Kaartinen, IS

“…Keloids have high recurrence rates. Current first-line therapy is triamcinolone (TAC) injection, but it has been suggested that approximately 50% of keloids…”
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Community size can affect the signals of ecological drift and niche selection on biodiversity by Siqueira, Tadeu, Saito, Victor S., Bini, Luis M., Melo, Adriano S., Petsch, Danielle K., Landeiro, Victor L., Tolonen, Kimmo T., Jyrkänkallio-Mikkola, Jenny, Soininen, Janne, Heino, Jani

“…Ecological drift can override the effects of deterministic niche selection on small populations and drive the assembly of some ecological communities. We…”
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Prostate cancer evolution from multilineage primary to single lineage metastases with implications for liquid biopsy by Woodcock, D. J., Riabchenko, E., Taavitsainen, S., Kankainen, M., Gundem, G., Brewer, D. S., Ellonen, P., Lepistö, M., Golubeva, Y. A., Warner, A. C., Tolonen, T., Jasu, J., Isaacs, W. B., Emmert-Buck, M. R., Nykter, M., Visakorpi, T., Bova, G. S., Wedge, D. C.

“…The evolutionary progression from primary to metastatic prostate cancer is largely uncharted, and the implications for liquid biopsy are unexplored. We infer…”
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Does catchment geodiversity foster stream biodiversity? by Kärnä, Olli-Matti, Heino, Jani, Laamanen, Tiina, Jyrkänkallio-Mikkola, Jenny, Pajunen, Virpi, Soininen, Janne, Tolonen, Kimmo T., Tukiainen, Helena, Hjort, Jan

“…Context One approach to maintain the resilience of biotic communities is to protect the variability of abiotic characteristics of Earth’s surface, i.e…”
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P182 Factors Influencing Breast Cancer Resection Volumes and their Impact on Treatment Outcome: Multi-center Prospective Study (FIBRATIO) – Study Protocol and Preliminary Results by Karhunen-Enckell, U., Salminen, A., Tolonen, T., Sarantola, H., Oksala, N., Roine, A.

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Assessing the Potential of Environmental DNA for Monitoring Nature‐Like Bypasses: Erroneous Surveillance Owing to DNA Flow‐Through by Tolonen, Kimmo T., Lehtinen, Anne, Laamanen, Tiina, Koljonen, Saija

“…ABSTRACT Nature‐like bypasses refer to fishways that simulate natural streams. Apart from facilitating fish migrations, bypasses possess the capacity to…”
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Geography of global change and species richness in the North by Vilmi, Annika, Alahuhta, Janne, Hjort, Jan, Kärnä, Olli-Matti, Leinonen, Kirsti, Rocha, Mariana Perez, Tolonen, Katri E, Tolonen, Kimmo T, Heino, Jani

“…Different components of global change (e.g., climate change, land use, pollution, and introduced species) continue to alter biodiversity worldwide. As northern…”
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P5 First screening round results of the ProScreen trial with PSA, kallikrein panel and MRI by Rannikko, A.S., Tammela, T.L.J., Mirtti, T., Lilja, H., Tolonen, T., Kenttämies, A., Rinta-Kiikka, I., Lehtimäki, T., Natunen, K., Nevalainen, J., Raitanen, J., Ronkainen, J., van der Kwast, T., Riikonen, J., Petas, A., Matikainen, M., Taari, K., Kilpeläinen, T.

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A computationally efficient multipitch analysis model by Tolonen, T., Karjalainen, M.

“…A computationally efficient model for multipitch and periodicity analysis of complex audio signals is presented. The model essentially divides the signal into…”
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Untangling the assembly of littoral macroinvertebrate communities through measures of functional and phylogenetic alpha diversity by Heino, Jani, Tolonen, Kimmo T.

“…Recent studies have shown that species, functional and phylogenetic diversity are related to different environmental drivers, suggesting that different aspects…”
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Relative roles of spatial processes, natural factors and anthropogenic stressors in structuring a lake macroinvertebrate metacommunity by Cai, Yongjiu, Xu, Hao, Vilmi, Annika, Tolonen, Kimmo T., Tang, Xiangming, Qin, Boqiang, Gong, Zhijun, Heino, Jani

“…Studies of aquatic metacommunities have so far been focused almost entirely on relatively isolated systems, such as a set of streams, lakes or ponds. Here, we…”
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Lakes in the era of global change: moving beyond single‐lake thinking in maintaining biodiversity and ecosystem services by Heino, Jani, Alahuhta, Janne, Bini, Luis Mauricio, Cai, Yongjiu, Heiskanen, Anna‐Stiina, Hellsten, Seppo, Kortelainen, Pirkko, Kotamäki, Niina, Tolonen, Kimmo T., Vihervaara, Petteri, Vilmi, Annika, Angeler, David G.

“…ABSTRACT The Anthropocene presents formidable threats to freshwater ecosystems. Lakes are especially vulnerable and important at the same time. They cover only…”
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Taxonomic distinctness along nutrient gradients: More diverse, less diverse or not different from random? by Vilmi, Annika, Karjalainen, Satu Maaria, Kuoppala, Minna, Tolonen, Kimmo T., Heino, Jani

“…•We compared taxonomic distinctness (TD) and richness of freshwater organismal groups.•The TD indices showed opposite patterns in relation to nutrient…”
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Overall and worst gleason scores are equally good predictors of prostate cancer progression by Tolonen, Teemu T, Kujala, Paula M, Tammela, Teuvo L J, Tuominen, Vilppu J, Isola, Jorma J, Visakorpi, Tapio

“…Gleason scoring has experienced several modifications during the past decade. So far, only one study has compared the prognostic abilities of worst (WGS) and…”
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Catastrophic effects of sand mining on macroinvertebrates in a large shallow lake with implications for management by Zou, Wei, Tolonen, Kimmo T., Zhu, Guangwei, Qin, Boqiang, Zhang, Yunling, Cao, Zhigang, Peng, Kai, Cai, Yongjiu, Gong, Zhijun

“…Sand mining is a human activity that is increasing in inland waters and has profound effects on entire aquatic ecosystems. However, current knowledge of the…”
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Dual‐specificity phosphatase 1 and serum/glucocorticoid‐regulated kinase are downregulated in prostate cancer by Rauhala, Hanna E., Porkka, Kati P., Tolonen, Teemu T., Martikainen, Paula M., Tammela, Teuvo L.J., Visakorpi, Tapio

“…Inactivation of tumor suppressor genes through deletion, mutation and epigenetic silencing has been shown to occur in cancer. In our study, we combined DNA…”
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Metacommunity structuring in a highly-connected aquatic system: effects of dispersal, abiotic environment and grazing pressure on microalgal guilds by Vilmi, Annika, Tolonen, Kimmo T., Karjalainen, Satu M., Heino, Jani

“…Associating a deconstructive approach with metacommunity ecology brings insights into how biological communities are structured. We examined the effects of…”
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