Search Results - "Tolliday, N"
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ChemBank: a small-molecule screening and cheminformatics resource database
Published in Nucleic acids research (01-01-2008)“…ChemBank (http://chembank.broad.harvard.edu/) is a public, web-based informatics environment developed through a collaboration between the Chemical Biology…”
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Phosphorylation in halobacterial signal transduction
Published in The EMBO journal (01-09-1995)“…Regulated phosphorylation of proteins has been shown to be a hallmark of signal transduction mechanisms in both Eubacteria and Eukarya. Here we demonstrate…”
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Structure determination of the glutamate dehydrogenase from the hyperthermophile Thermococcus litoralis and its comparison with that from Pyrococcus furiosus
Published in Journal of molecular biology (12-11-1999)“…Glutamate dehydrogenase catalyses the oxidative deamination of glutamate to 2-oxoglutarate with concomitant reduction of NAD(P)(+), and has been shown to be…”
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Pressure-induced thermostabilization of glutamate dehydrogenase from the hyperthermophile Pyrococcus furiosus
Published in Protein science (01-05-1999)“…In this paper, elevated pressures up to 750 atm (1 atm = 101 kPa) were found to have a strong stabilizing effect on two extremely thermophilic glutamate…”
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Glutamate dehydrogenases from hyperthermophiles
Published in Methods in enzymology (2001)Get more information
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Rho1 Directs Formin-Mediated Actin Ring Assembly during Budding Yeast Cytokinesis
Published in Current biology (29-10-2002)“…In eukaryotic cells, dynamic rearrangement of the actin cytoskeleton is critical for cell division. In the yeast Saccharomyces cerevisiae, three main…”
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Human genetics in rheumatoid arthritis guides a high-throughput drug screen of the CD40 signaling pathway
Published in PLoS genetics (01-05-2013)“…Although genetic and non-genetic studies in mouse and human implicate the CD40 pathway in rheumatoid arthritis (RA), there are no approved drugs that inhibit…”
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Direct evidence for a critical role of myosin II in budding yeast cytokinesis and the evolvability of new cytokinetic mechanisms in the absence of myosin II
Published in Molecular biology of the cell (01-02-2003)“…In the budding yeast Saccharomyces cerevisiae, an actomyosin-based contractile ring is present during cytokinesis, as occurs in animal cells. However, the…”
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Protein Thermostability above 100 degrees C: A Key Role for Ionic Interactions
Published in Proceedings of the National Academy of Sciences - PNAS (13-10-1998)“…The discovery of hyperthermophilic microorganisms and the analysis of hyperthermostable enzymes has established the fact that multisubunit enzymes can survive…”
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Assembly and regulation of the cytokinetic apparatus in budding yeast
Published in Current Opinion in Microbiology (01-12-2001)“…The identification of an actomyosin-based contractile ring in budding yeast has recently established this organism as a general model for studying cytokinesis…”
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Book Review Journal Article -
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Protein thermostability above 100 degree C: A key role for ionic interactions
Published in Proceedings of the National Academy of Sciences - PNAS (13-10-1998)“…The discovery of hyperthermophilic microorganisms and the analysis of hyperthermostable enzymes has established the fact that multisubunit enzymes can survive…”
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Journal Article -
13
Protein thermostability above 100 degreesC: a key role for ionic interactions
Published in Proceedings of the National Academy of Sciences - PNAS (13-10-1998)“…The discovery of hyperthermophilic microorganisms and the analysis of hyperthermostable enzymes has established the fact that multisubunit enzymes can survive…”
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Journal Article -
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Purification and characterization of HSP70 proteins from Torpedo electric organ
Published in Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology (01-02-1995)“…Members of the HSP70 family were purified from electric organ tissue of Torpedo californica by chromatography on an ATP-agarose column. A 70 kDa protein was…”
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