Search Results - "Tolias, K"

The Rac1-GEF Tiam1 Couples the NMDA Receptor to the Activity-Dependent Development of Dendritic Arbors and Spines by Tolias, Kimberley F., Bikoff, Jay B., Burette, Alain, Paradis, Suzanne, Harrar, Dana, Tavazoie, Sohail, Weinberg, Richard J., Greenberg, Michael E.

“…NMDA-type glutamate receptors play a critical role in the activity-dependent development and structural remodeling of dendritic arbors and spines. However, the…”
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Direct Interaction of the Wiskott-Aldrich Syndrome Protein with the GTPase Cdc42 by Kolluri, Rikki, Tolias, Kimberley Fuchs, Carpenter, Christopher L., Rosen, Fred S., Kirchhausen, Tomas

“…Wiskott-Aldrich syndrome (WAS) is an X-linked immunodeficiency disorder with the most severe pathology in the T lymphocytes and platelets. The disease arises…”
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A new pathway for synthesis of phosphatidylinositol-4,5-bisphosphate by Rameh, Lucia E, Tolias, Kimberley F, Duckworth, Brian C, Cantley, Lewis C

“…Phosphatidylinositol-4,5-bisphosphate (PtdIns-4,5-P2), a key molecule in the phosphoinositide signalling pathway, was thought to be synthesized exclusively by…”
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Rho Family GTPases Bind to Phosphoinositide Kinases by Tolias, K F, Cantley, L C, Carpenter, C L

“…Rho family GTPases appear to play an important role in the regulation of the actin cytoskeleton, but the mechanism of regulation is unknown. Since…”
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Characterization of a Rac1- and RhoGDI-Associated Lipid Kinase Signaling Complex by Tolias, Kimberley F., Couvillon, Anthony D., Cantley, Lewis C., Carpenter, Christopher L.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Type I Phosphatidylinositol-4-phosphate 5-Kinases Synthesize the Novel Lipids Phosphatidylinositol 3,5-Bisphosphate and Phosphatidylinositol 5-Phosphate by Tolias, K F, Rameh, L E, Ishihara, H, Shibasaki, Y, Chen, J, Prestwich, G D, Cantley, L C, Carpenter, C L

“…Inositol phospholipids regulate a variety of cellular processes including proliferation, survival, vesicular trafficking, and cytoskeletal organization…”
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Pathways for phosphoinositide synthesis by Tolias, Kimberley F., Cantley, Lewis C.

“…In eukaryotic cells, phosphatidylinositol can be phosphorylated on the inositol ring by a series of kinases to produce at least seven distinct…”
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A Novel Link between Integrins, Transmembrane-4 Superfamily Proteins (CD63 and CD81), and Phosphatidylinositol 4-Kinase by Berditchevski, Fedor, Tolias, Kimberly F., Wong, Karen, Carpenter, Christopher L., Hemler, Martin E.

“…Enzymatic and immunochemical assays show a phosphatidylinositol 4-kinase in novel and specific complexes with proteins (CD63 and CD81) of the transmembrane 4…”
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Rac homologues and compartmentalized phosphatidylinositol 4, 5-bisphosphate act in a common pathway to regulate polar pollen tube growth by Kost, B. (National University of Singapore, Singapore.), Lemichez, E, Spielhofer, P, Hong, Y, Tolias, K, Carpenter, C, Chua, N.H

“…Pollen tube cells elongate based on actin-dependent targeted secretion at the tip. Rho family small GTPases have been implicated in the regulation of related…”
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Electrophysiological, transcriptomic and morphologic profiling of single neurons using Patch-seq by Cadwell, Cathryn R, Palasantza, Athanasia, Jiang, Xiaolong, Berens, Philipp, Deng, Qiaolin, Yilmaz, Marlene, Reimer, Jacob, Shen, Shan, Bethge, Matthias, Tolias, Kimberley F, Sandberg, Rickard, Tolias, Andreas S

“…Patch-seq reveals new neuronal subtypes by combining electrophysiological and RNA-seq data on single neurons in situ . Despite the importance of the mammalian…”
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Cell type composition and circuit organization of clonally related excitatory neurons in the juvenile mouse neocortex by Cadwell, Cathryn R, Scala, Federico, Fahey, Paul G, Kobak, Dmitry, Mulherkar, Shalaka, Sinz, Fabian H, Papadopoulos, Stelios, Tan, Zheng H, Johnsson, Per, Hartmanis, Leonard, Li, Shuang, Cotton, Ronald J, Tolias, Kimberley F, Sandberg, Rickard, Berens, Philipp, Jiang, Xiaolong, Tolias, Andreas Savas

“…Clones of excitatory neurons derived from a common progenitor have been proposed to serve as elementary information processing modules in the neocortex. To…”
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In vitro interaction of phosphoinositide-4-phosphate 5-kinases with Rac by Tolias, K, Carpenter, C L

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BTK Regulates PtdIns-4, 5-P sub(2) Synthesis Importance for Calcium Signaling and PI3K Activity by Saito, K, Tolias, K F, Saci, A, Koon, H B, Humphries, LA, Scharenberg, A, Rawlings, D J, Kinet, J-P, Carpenter, CL

“…Intracellular signaling by most cell surface receptors requires the generation of two major second messengers, phosphatidylinositol-3, 4, 5- trisphosphate…”
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Type Iα phosphatidylinositol-4-phosphate 5-kinase mediates Rac-dependent actin assembly by Tolias, Kimberley F., Hartwig, John H., Ishihara, Hisamitsu, Shibasaki, Yoshikazu, Cantley, Lewis C., Carpenter, Christopher L.

“…Actin polymerization is essential for a variety of cellular processes including movement, cell division and shape change. The induction of actin polymerization…”
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Type Ialpha phosphatidylinositol-4-phosphate 5-kinase mediates Rac-dependent actin assembly by Tolias, K F, Hartwig, J H, Ishihara, H, Shibasaki, Y, Cantley, L C, Carpenter, C L

“…Action polymerization is essential for a variety of cellular processes including movement, cell division and shape change. The induction of actin…”
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Lipid kinases are novel effectors of the GTPase Rac1 by Carpenter, C L, Tolias, K F, Van Vugt, A, Hartwig, J

“…We have found that a complex consisting of a type I PIPK and a DGK associates with the GTPase Rac1. Binding of the lipid kinase complex is through the…”
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Signal transduction pathways involving the small G proteins rac and Cdc42 and phosphoinositide kinases by Carpenter, Christopher L., Tolias, Kimberley F., Couvillon, Anthony C., Hartwig, John H.

“…We found that rac specifically binds to a type I PtdIns-4-P 5-kinase and that both rac and Cdc42 in the activated forms associate with PI 3-kinase. The…”
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A new pathway for synthesis of phosphatidylinositol-4,6-bisphosphate by RAMEH, L. E, TOLIAS, K. F, DUCKWORTH, B. C, CANTLEY, L. C

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Spike train encoding of analog signals in a graphene fiber ring laser by Tolias, Leonidas K., Shastri, Bhavin J., Nahmias, Mitchell M., Tait, Alexander N., de Lima, Thomas Ferrieira, Prucnal, Paul R.

“…Spiking neural networks (SNN) have inherent advantages over traditional computing architectures for many computational problems such as adaptive control,…”
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