Screening for gestational diabetes mellitus: A prospective study in a tertiary care institution of North India

Aim: The aim of this study was to determine the relevance of universal screening for gestational diabetes mellitus (GDM) in the patients attending the antenatal clinic of a tertiary institute of North India. Material and Methods: This was a prospective study conducted on 700 pregnant women attendi...

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Published in:	The journal of obstetrics and gynaecology research Vol. 38; no. 2; pp. 351 - 357
Main Authors:	Tripathi, Reva, Tolia, Nalini, Gupta, Vinod Kumar, Mala, Yedla Manikya, Ramji, Siddarth, Tyagi, Shakun
Format:	Journal Article
Language:	English
Published:	Melbourne, Australia Blackwell Publishing Asia 01-02-2012
Subjects:	Adult Diabetes, Gestational - epidemiology Female gestational diabetes mellitus glucose challenge test Glucose Tolerance Test Humans India - epidemiology Infant, Newborn oral glucose tolerance test Pregnancy Prevalence prevalence in North India Prospective Studies Risk Factors universal screening India
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Summary:	Aim: The aim of this study was to determine the relevance of universal screening for gestational diabetes mellitus (GDM) in the patients attending the antenatal clinic of a tertiary institute of North India. Material and Methods: This was a prospective study conducted on 700 pregnant women attending the antenatal clinic of Lok Nayak Hospital, New Delhi at or before 24 weeks of gestation. All patients underwent screening with a 50‐g 1‐h glucose challenge test at 24–28 weeks of gestation. The women with an abnormal glucose challenge test subsequently underwent a diagnostic 3‐h oral glucose tolerance test. All the patients were followed up till delivery. Results: Out of 700, thirteen patients were lost to follow up and hence the final outcomes were measured on 687 patients. Out of 687, 613 patients (89.2%) had a normal glucose challenge test value, that is, <140 mg%, and 74 (10.8%) had a glucose challenge test value ≥140 mg%. On the subsequent oral glucose tolerance test, 64 (9.3%) had normal values and only 10 (1.5%) had an abnormal oral glucose tolerance test, that is, GDM. Conclusion: With such a low prevalence rate it appears to be unjustified to recommend universal screening for GDM. These findings may be considered as a basis for conducting larger, multicentric studies to establish the prevalence rate of GDM before deciding on a policy for screening.
Bibliography:	istex:954CE4A2CBFC420D1BF294A9428B9CA5579E73B1 ArticleID:JOG1706 ark:/67375/WNG-457VP6PC-M ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	1341-8076 1447-0756
DOI:	10.1111/j.1447-0756.2011.01706.x