Search Results - "Tolić, Anja"
-
1
Synchrotron-based FTIR microspectroscopy reveals DNA methylation profile in DNA-HALO structure
Published in Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy (05-12-2023)“…[Display omitted] •Synchrotron-based FTIR analysis reveals subtle changes in DNA methylation status.•Changes in DNA conformation lead to changes in IR…”
Get full text
Journal Article -
2
Absence of PARP‐1 affects Cxcl12 expression by increasing DNA demethylation
Published in Journal of cellular and molecular medicine (01-04-2019)“…Poly [ADP‐ribose] polymerase 1 (PARP‐1) has an inhibitory effect on C‐X‐C motif chemokine 12 gene (Cxcl12) transcription. We examined whether PARP‐1 affects…”
Get full text
Journal Article -
3
α-Lipoic Acid Increases Collagen Synthesis and Deposition in Nondiabetic and Diabetic Rat Kidneys
Published in Oxidative medicine and cellular longevity (2021)“…α-Lipoic acid (ALA) is widely used as a nutritional supplement and therapeutic agent in diabetes management. Well-established antioxidant and hypoglycemic…”
Get full text
Journal Article -
4
Centaurium erythraea extract reduces redox imbalance and improves insulin expression and secretion in pancreatic β-cells exposed to oxidative and nitrosative stress
Published in Archives of biological sciences (2020)“…Oxidative stress is one of the major mechanisms that underlies the damage of pancreatic ?-cells and defects in insulin secretion in diabetes. As herbal…”
Get full text
Journal Article -
5
Enrichment of Cxcl12 promoter with TET2: A possible link between promoter demethylation and enhanced gene expression in the absence of PARP-1
Published in Archives of biological sciences (2019)“…Previously, we described the link between C-X-C motif chemokine 12 (Cxcl12) gene induction and DNA hypomethylation in the absence of poly(ADP-ribose)…”
Get full text
Journal Article -
6
Association of CXCL12 gene promoter methylation with periodontitis in patients with diabetes mellitus type 2
Published in Archives of oral biology (01-12-2016)“…Highlights • Impairment in periodontal parameters was detected in D/P group relative to P group. • The highest percent of CXCL12 DNA methylation is observed in…”
Get full text
Journal Article -
7
CXC chemokine ligand 12α-mediated increase in insulin secretion and survival of mouse pancreatic islets in response to oxidative stress through modulation of calcium uptake
Published in Archives of biological sciences (2018)“…We examined whether CXCL12? improves insulin secretion by influencing the Ca2+ oscillation pattern and Ca2+ influx ([Ca2+]i), thereby enhancing the viability…”
Get full text
Journal Article -
8
Oxidative stress-mediated beta cell death and dysfunction as a target for diabetes management
Published in Frontiers in endocrinology (Lausanne) (23-09-2022)“…The biggest drawback of a current diabetes therapy is the treatment of the consequences not the cause of the disease. Regardless of the diabetes type,…”
Get full text
Journal Article -
9
DNA methylation of miR-200 clusters promotes epithelial to mesenchymal transition in human conjunctival epithelial cells
Published in Experimental eye research (01-08-2020)“…Epithelial to mesenchymal transition (EMT) contributes to fibrosis associated pathologies including scarring of different ocular tissues. Recently targeting…”
Get full text
Journal Article -
10
Centaurium erythraea extract improves survival and functionality of pancreatic beta-cells in diabetes through multiple routes of action
Published in Journal of ethnopharmacology (05-10-2019)“…Centaurium erythraea Rafn (CE) is used as a traditional medicinal plant in Serbia to treat different ailments due to its antidiabetic, antipyretic,…”
Get full text
Journal Article -
11
Centaurium erythraea methanol extract improves the functionality of diabetic liver and kidney by mitigating hyperglycemia-induced oxidative stress
Published in Journal of functional foods (01-03-2022)“…[Display omitted] •Persistent oxidative stress leads to the development of diabetic complications.•Centaurium erythraea extract (CEE) reduced protein…”
Get full text
Journal Article -
12
EpiCRISPR targeted methylation of Arx gene initiates transient switch of mouse pancreatic alpha to insulin-producing cells
Published in Frontiers in endocrinology (Lausanne) (16-03-2023)“…Beta cell dysfunction by loss of beta cell identity, dedifferentiation, and the presence of polyhormonal cells are main characteristics of diabetes. The…”
Get full text
Journal Article -
13
Centaurium erythraea methanol extract protects red blood cells from oxidative damage in streptozotocin-induced diabetic rats
Published in Journal of ethnopharmacology (18-04-2017)“…Centaurium erythraea Rafn (CE) is a traditional medicinal herb in Serbia with antidiabetic, digestive, antipyretic and antiflatulent effects To investigate the…”
Get full text
Journal Article -
14
TET-mediated DNA hydroxymethylation is negatively influenced by the PARP-dependent PARylation
Published in Epigenetics & chromatin (05-04-2022)“…Poly(ADP-ribosyl)ation (PARylation), a posttranslational modification introduced by PARP-1 and PARP-2, has first been implicated in DNA demethylation due to…”
Get full text
Journal Article -
15
Nucleofection as an Efficient Method for Alpha TC1-6 Cell Line Transfection
Published in Applied sciences (01-08-2022)“…An efficient transfection is a crucial step for the introduction of epigenetic modification in host cells, and there is a need for an optimized transfection…”
Get full text
Journal Article -
16
Biochemical indicators and biomarkers in chub (Squalius cephalus L.) from the Sava River
Published in The Science of the total environment (01-01-2016)“…Biochemical indicators and biomarkers were analyzed in the liver and gills of chub caught in three localities along the Sava River exposed to different…”
Get full text
Journal Article -
17
Funkcionalna Analiza Interakcija Tet-Posredovane Oksidacije 5-Metilcitozina i Parp-Zavisne Adp-Ribozilacije u Procesu Demetilacije DNK
Published 01-01-2019“…Važan aspekt u rasvetljavanju procesa demetilacije DNK predstavlja identifikacija faktora koji regulušu aktivnost TET proteina. Cilj ove doktorske disertacije…”
Get full text
Dissertation