Search Results - "Toleikis, Philip M."

Subcutaneous transplantation of human thyroid tissue into a pre-vascularized Cell Pouch™ device in a Mus musculus model: Evidence of viability and function for thyroid transplantation by Wiseman, Sam M, Memarnejadian, Arash, Boyce, Guilaine K, Nguyen, Anne, Walker, Blair A, Holmes, Daniel T, Welch, Ian D, Mazzuca, Delfina M, Toleikis, Philip M

“…This study aimed to investigate the survival and efficacy indicators of human thyroid tissue transplantation into a retrievable, prevascularized implanted…”
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Microtubule-Binding Drugs Offset Tau Sequestration by Stabilizing Microtubules and Reversing Fast Axonal Transport Deficits in a Tauopathy Model by Zhang, Bin, Maiti, Arpita, Shively, Sharon, Lakhani, Fara, McDonald-Jones, Gaye, Bruce, Jennifer, Lee, Edward B., Xie, Sharon X., Joyce, Sonali, Li, Chi, Toleikis, Philip M., Virginia M.-Y. Lee, Trojanowski, John Q., Iversen, L. L.

“…We tested the hypothesis that microtubule (MT)-binding drugs could be therapeutically beneficial in tauopathies by functionally substituting for the MT-binding…”
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A novel technique for the transplantation of pancreatic islets within a vascularized device into the greater omentum to achieve insulin independence by Kriz, Jan, M.D., Ph.D, Vilk, Greg, Ph.D, Mazzuca, Delfina M., M.Sc, Toleikis, Philip M., Ph.D, Foster, Paula J., Ph.D, White, David J.G., Ph.D., F.R.C.Path

“…Abstract Background The greater omentum with its vascularization and blood flow has been considered as a location for islet transplantation; however, there is…”
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Efficient and safe correction of hemophilia A by lentiviral vector-transduced BOECs in an implantable device by Olgasi, Cristina, Borsotti, Chiara, Merlin, Simone, Bergmann, Thorsten, Bittorf, Patrick, Adewoye, Adeolu Badi, Wragg, Nicholas, Patterson, Kelcey, Calabria, Andrea, Benedicenti, Fabrizio, Cucci, Alessia, Borchiellini, Alessandra, Pollio, Berardino, Montini, Eugenio, Mazzuca, Delfina M., Zierau, Martin, Stolzing, Alexandra, Toleikis, Philip.M., Braspenning, Joris, Follenzi, Antonia

“…Hemophilia A (HA) is a rare bleeding disorder caused by deficiency/dysfunction of the FVIII protein. As current therapies based on frequent FVIII infusions are…”
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Inhibition of neointimal hyperplasia in a sheep model of dialysis access failure with the bioabsorbable Vascular Wrap ⁎ paclitaxel-eluting mesh by Kohler, Ted R., MD, MSc, Toleikis, Philip M., PhD, Gravett, David M., PhD, Avelar, Rui L., MD

“…Objective This study evaluated the effect of a bioabsorbable mesh containing paclitaxel on neointimal hyperplasia in a sheep model of dialysis access failure…”
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205-LB: Clinical Validation of the Implanted Prevascularized Cell Pouch as a Viable, Safe Site for Diabetes Cell Therapy by MACGILLIVARY, AMANDA S., TOLEIKIS, PHILIP M., MAZZUCA, DELFINA M.

“…We report current clinical findings for the Cell Pouch (CP), as an implantable and retrievable medical device designed to develop a healthy vascularized tissue…”
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Diabetes Is Reversed in a Murine Model by Marginal Mass Syngeneic Islet Transplantation Using a Subcutaneous Cell Pouch Device by Pepper, Andrew R, Pawlick, Rena, Gala-Lopez, Boris, MacGillivary, Amanda, Mazzuca, Delfina M, White, David J G, Toleikis, Philip M, Shapiro, A. M James

“…BACKGROUNDIslet transplantation is a successful β-cell replacement therapy for selected patients with type 1 diabetes mellitus. Although high rates of early…”
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Diabetes Is Reversed in a Murine Model by Marginal Mass Syngeneic Islet Transplantation Using a Subcutaneous Cell Pouch Device by Pepper, Andrew R., Pawlick, Rena, Gala-Lopez, Boris, MacGillivary, Amanda, Mazzuca, Delfina M., White, David J. G., Toleikis, Philip M., Shapiro, A. M. James

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Intrapericardial paclitaxel delivery inhibits neointimal proliferation and promotes arterial enlargement after porcine coronary overstretch by DONGMING HOU, ROGERS, Pamela I, TOLEIKIS, Philip M, HUNTER, William, MARCH, Keith L

“…Catheter-based intrapericardial (IPC) delivery of therapeutic agents has recently been demonstrated. Paclitaxel is known to inhibit vascular smooth muscle cell…”
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Alteration of antioxidant status in diabetic rats by chronic exposure to psychological stressors by Toleikis, Philip M., Godin, David V.

“…Antioxidant status was measured in heart, liver, kidney, lung, and erythrocytes of 2-week streptozotocin-diabetic male Wistar rats exposed to chronic…”
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Myocardial functional preservation during ischemia: influence of beta blocking agents by Toleikis, P M, Tomlinson, C W

“…To determine whether prior acute Beta blockade protects the heart against the deleterious effects of normothermic low flow global ischemia on myocardial…”
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Inhibition of neointimal hyperplasia in a sheep model of dialysis access failure with the bioabsorbable Vascular Wrap ⁎ ⁎ Vascular Wrap is a trademark of Angiotech Pharmaceuticals, Inc. paclitaxel-eluting mesh by Kohler, Ted R., Toleikis, Philip M., Gravett, David M., Avelar, Rui L.

“…This study evaluated the effect of a bioabsorbable mesh containing paclitaxel on neointimal hyperplasia in a sheep model of dialysis access failure. Forty…”
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P1-360 Dose dependent improvements of fast axonal transport and motor impairment in PRPT44 tau transgenic mice treated with a MT stabilizing drug by Zhang, Bin, Maiti, Arpita, Shivly, Sharon, Lakhani, Fara, McDonald-Jones, Gaye, Bruce, Jennifer, Lee, Eddie, Sundarraj, Sonali, Li, Chi, Toleikis, Philip M., Lee, Virginia M.-Y., Trojanowski, John Q.

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Alteration of antioxidant status following sympathectomy: differential effects of modified plasma levels of adrenaline and noradrenaline by Toleikis, P M, Godin, D V

“…The influence of altered levels of endogenous catecholamines following adrenalectomy or 6-hydroxydopamine (6-OH) treatment (alone or in combination) on…”
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Evaluation of ventricular contractility indexes in the dog with left ventricular dysfunction induced by rapid atrial pacing by Morgan, Dennis E., Tomlinson, Charles W., Karim Qayumi, A., Toleikis, Philip M., McConville, Briege, Eric Jamieson, W.R.

“…Eight dogs were studied by simultaneous invasive hemodynamic and two-dimensional echocardiographic methods to determine whether left ventricular contractility…”
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