Search Results - "Toledo, Silvia R"

Glutathione S-transferase polymorphisms in osteosarcoma patients by Salinas-Souza, Carolina, Petrilli, Antonio S, de Toledo, Silvia R.C

“…BACKGROUNDOsteosarcoma is the most common malignant bone tumor in children and adolescents. Multidrug resistance and poor clinical outcome are the problems…”
Get full text

Effects of THBS3, SPARC and SPP1 expression on biological behavior and survival in patients with osteosarcoma by Dalla-Torre, Cristiane A, Yoshimoto, Maisa, Lee, Chung-Hae, Joshua, Anthony M, de Toledo, Silvia R C, Petrilli, Antônio S, Andrade, Joyce A D, Chilton-MacNeill, Susan, Zielenska, Maria, Squire, Jeremy A

“…Osteosarcoma is a very aggressive tumor with a propensity to metastasize and invade surrounding tissue. Identification of the molecular determinants of…”
Get full text

A simplified minimal residual disease polymerase chain reaction method at early treatment points can stratify children with acute lymphoblastic leukemia into good and poor outcome groups by Scrideli, Carlos A, Assumpcao, Juliana G, Ganazza, Monica A, Araujo, Marcela, Toledo, Silvia R, Lee, Maria Lucia M, Delbuono, Elisabete, Petrilli, Antonio S, Queiroz, Rosane P, Biondi, Andrea, Viana, Marcos B, Yunes, Jose A, Brandalise, Silvia R, Tone, Luiz G

“…1 Department of Pediatrics, Ribeirao Preto Medical School, University of São Paulo, Ribeirao Preto, Brazil 2 Centro Infantil Boldrini, Campinas, Brazil 3…”
Get full text

mRNA expression profile of multidrug resistance genes in childhood acute lymphoblastic leukemia. Low expression levels associated with a higher risk of toxic death by Cortez, Maria A.A., Scrideli, Carlos A., Yunes, José A., Valera, Elvis T., Toledo, Sílvia R.C., Pavoni-Ferreira, Patrícia C.B., Lee, Maria L.M., Petrilli, Antônio S., Brandalise, Silvia R., Tone, Luiz G.

“…Background Increased activity of multidrug resistance (MDR) genes has been associated with treatment failure in acute leukemias, although with controversial…”
Get full text

Low mRNA expression of the apoptosis-related genes CASP3, CASP8, and FAS is associated with low induction treatment response in childhood acute lymphoblastic leukemia (ALL) by Mata, Juliana F., Silveira, Vanessa S., Mateo, Elvis C., Cortez, Maria A.A., Queiroz, Rosane G.P., Yunes, José Andrés, Lee, Maria Lúcia M., Toledo, Sílvia R.C., Petrilli, Antonio Sérgio, Brandalise, Silvia R., Tone, Luiz G., Scrideli, Carlos A.

“…Background Defects in apoptosis signaling have been considered to be responsible for treatment failure in many types of cancer, although with controversial…”
Get full text

Immuno-transcriptomic profiling of extracranial pediatric solid malignancies by Brohl, Andrew S., Sindiri, Sivasish, Wei, Jun S., Milewski, David, Chou, Hsien-Chao, Song, Young K., Wen, Xinyu, Kumar, Jeetendra, Reardon, Hue V., Mudunuri, Uma S., Collins, Jack R., Nagaraj, Sushma, Gangalapudi, Vineela, Tyagi, Manoj, Zhu, Yuelin J., Masih, Katherine E., Yohe, Marielle E., Shern, Jack F., Qi, Yue, Guha, Udayan, Catchpoole, Daniel, Orentas, Rimas J., Kuznetsov, Igor B., Llosa, Nicolas J., Ligon, John A., Turpin, Brian K., Leino, Daniel G., Iwata, Shintaro, Andrulis, Irene L., Wunder, Jay S., Toledo, Silvia R.C., Meltzer, Paul S., Lau, Ching, Teicher, Beverly A., Magnan, Heather, Ladanyi, Marc, Khan, Javed

“…We perform an immunogenomics analysis utilizing whole-transcriptome sequencing of 657 pediatric extracranial solid cancer samples representing 14 diagnoses,…”
Get full text

Craniopharyngiomas: intratumoral chemotherapy with interferon-alpha: a multicenter preliminary study with 60 cases by Cavalheiro, Sergio, Di Rocco, Concezzio, Valenzuela, Sergio, Dastoli, Patricia A, Tamburrini, Gianpiero, Massimi, Lucca, Nicacio, Jardel M, Faquini, Igor V, Ierardi, Daniela F, Silva, Nasjla S, Pettorini, Benedetta Ludovica, Toledo, Silvia R C

“…The authors assessed the efficacy of intratumoral interferon-alpha (IFNalpha)-based chemotherapy in pediatric patients with cystic craniopharyngiomas. In a…”
Get full text

A Novel Germ-Line Point Mutation in RET Exon 8 (Gly533Cys) in a Large Kindred with Familial Medullary Thyroid Carcinoma by Álvares Da Silva, Adriana M., Maciel, Rui M. B., Dias Da Silva, Magnus R., Toledo, Silvia R. C., De Carvalho, Marcos B., Cerutti, Janete M.

“…Familial medullary thyroid carcinoma is related to germ-line mutations in the RET oncogene, mainly in cysteine codon 10 or 11, whereas noncysteine mutations in…”
Get full text

Expression of integrin genes and proteins in progression and dissemination of colorectal adenocarcinoma by Denadai, Marcos Va, Viana, Luciano S, Affonso, Jr, Renato J, Silva, Sandra R, Oliveira, Indhira D, Toledo, Silvia R, Matos, Delcio

“…This study aimed to evaluate the relationship between the expression levels of selected integrin genes and proteins and cell differentiation, TNM stage,…”
Get full text

Cystic craniopharyngioma: intratumoral chemotherapy with alpha interferon by Dastoli, Patrícia Alessandra, Nicácio, Jardel Mendonça, Silva, Nasjla Saba, Capellano, Andrea Maria, Toledo, Silvia R C, Ierardi, Daniela, Cavalheiro, Sérgio

“…To assess whether the cystic craniopharyngiomas can be controlled with the use of intratumoral applications of interferon alpha. Nineteen patients with the…”
Get full text

Aberrant DNA methylation of ESR1 and p14ARF genes could be useful as prognostic indicators in osteosarcoma by Sonaglio, Viviane, de Carvalho, Ana C, Toledo, Silvia R C, Salinas-Souza, Carolina, Carvalho, André L, Petrilli, Antonio S, de Camargo, Beatriz, Vettore, André L

“…Osteosarcoma (OS) is the eighth most common form of childhood and adolescence cancer. Approximately 10%-20% of patients present metastatic disease at diagnosis…”
Get full text

C-kit expression in human osteosarcoma and in vitro assays by Miiji, Luciana N O, Petrilli, Antonio S, Di Cesare, Sebastian, Odashiro, Alexandre N, Burnier, Jr, Miguel N, de Toledo, Silvia R, Garcia, Reynaldo Jesus, Alves, Maria Teresa S

“…Biologic agents targeting oncogenes have encourage researchs trying to correlate the role of tyrosine kinase in the pathogenesis of tumours. Osteosarcoma is a…”
Get full text

LMIC-12. INFANT-TYPE HEMISPHERIC GLIOMA: CAN IT BE EFFECTIVELY MANAGED IN AN UPPER-MIDDLE-INCOME COUNTRY? by Dassi, Natália, Balsanelli, Julia D, Toledo, Silvia R C, Gamba, Francine T, Alves, Maria T S, Cavalheiro, Sergio, Dastoli, Patricia A, Costa, Marcos D, Silva, Frederico A, Silva, Nasjla S, Cappellano, Andrea M

Get full text

Role of glutathione S-transferase and cytochrome P-450 polymorphisms in the clinical outcome of osteosarcoma patients by Trujillo-Paolillo, Alini, Salinas-Souza, Carolina, Dias-Oliveira, Indhira, Petrilli, Antonio Sergio, Toledo, Silvia R. C.

“…Abstract only 10535 Background: Osteosarcoma (OS) is the most common malignant bone tumor in children and adolescents. Glutathione S-transferase (GST) and…”
Get full text

Gene expression of the MAPK pathway in osteosarcoma by Lopes, Luana Joyce Silva, Petrilli, Antonio Sergio, Tesser-Gamba, Francine, Alves, Maria Teresa Seixas, Garcia-Filho, Reynaldo Jesus, Toledo, Silvia R. C.

“…Abstract only 10534 Background: Osteosarcoma (OS) is the most common malignant bone tumor in adolescents. A feature of the OS is its high risk of lung…”
Get full text

MAPK7 gene: A target for multimodal therapies by Tesser-Gamba, Francine, Petrilli, Antonio Sergio, Paniago, Mario Del Giudice, Alves, Maria Teresa Seixas, Garcia-Filho, Reynaldo Jesus, Toledo, Silvia R. C.

“…Abstract only 10533 Background: Osteosarcoma (OS) is a class of cancer originating from the bone, affecting mainly children and young adults. In a previous…”
Get full text

A novel germ-line point mutation in RET exon 8 (Gly(533)Cys) in a large kindred with familial medullary thyroid carcinoma by Da Silva, Adriana M Alvares, Maciel, Rui M B, Da Silva, Magnus R Dias, Toledo, Silvia R C, De Carvalho, Marcos B, Cerutti, Janete M

“…Familial medullary thyroid carcinoma is related to germ-line mutations in the RET oncogene, mainly in cysteine codon 10 or 11, whereas noncysteine mutations in…”
Get full text

Metaphase and array comparative genomic hybridization: unique copy number changes and gene amplification of medulloblastomas in South America by Yoshimoto, Maisa, Bayani, Jane, Nuin, Paulo A.S., Silva, Nasjla S., Cavalheiro, Sergio, Stavale, João N., Andrade, Joyce A.D., Zielenska, Maria, Squire, Jeremy A., de Toledo, Silvia R.C.

“…Tumors of the central nervous system are the second most frequent malignancy of childhood, accounting for the majority of cancer-related deaths in this age…”
Get full text