Search Results - "Toledo, Maria Pilar"
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NKX2-2 based nuclei sorting on frozen human archival pancreas enables the enrichment of islet endocrine populations for single-nucleus RNA sequencing
Published in BMC genomics (30-04-2024)“…Current approaches to profile the single-cell transcriptomics of human pancreatic endocrine cells almost exclusively rely on freshly isolated islets. However,…”
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Comprehensive Characterization of Islet Remodeling in Development and in Diabetes Using Mass Cytometry
Published in Endocrinology (Philadelphia) (26-07-2024)“…Abstract The pancreatic islet is the functional and structural unit of the pancreatic endocrine portion. Islet remodeling occurs in both normal development and…”
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Sex Differences in the Molecular Programs of Pancreatic Cells Contribute to the Differential Risks of Type 2 Diabetes
Published in Endocrinology (Philadelphia) (01-11-2022)“…Abstract Epidemiology studies demonstrate that women are at a significantly lower risk of developing type 2 diabetes (T2D) compared to men. However, the…”
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