Search Results - "Toledo, José Carlos"

Relationship between continuous improvement and innovation performance: an empirical study in Brazilian manufacturing companies by Lizarelli, Fabiane Letícia, de Toledo, José Carlos, Alliprandini, Dário Henrique

“…The continuous improvement programs and innovation have been stimulated and widely deployed due to the importance to the competitiveness of the organisations,…”
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Continuous improvement behaviors and impacts on innovation by Lizarelli, Fabiane Letícia, Toledo, José Carlos de, Gambi, Lillian Do Nascimento, Gonçalves, Celso Luiz

“…PurposeThis paper investigates whether adopting continuous improvement (CI) behaviors is related to better radical and incremental product and process…”
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Front-line lean leader capacities, practices and effects on implementing tools: a survey of leaders in industrial companies by Simões, Julianita Maria Scaranello, Toledo, José Carlos de, Lizarelli, Fabiane Letícia

“…Purpose Front-line lean leadership is critical for implementing and sustaining lean production systems (LPS). The purpose of this paper is to analyze the…”
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Horseradish peroxidase compound I as a tool to investigate reactive protein-cysteine residues: from quantification to kinetics by Toledo, José Carlos, Audi, Renata, Ogusucu, Renata, Monteiro, Gisele, Netto, Luis Eduardo Soares, Augusto, Ohara

“…Proteins containing reactive cysteine residues (protein-Cys) are receiving increased attention as mediators of hydrogen peroxide signaling. These proteins are…”
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Urate hydroperoxide oxidizes human peroxiredoxin 1 and peroxiredoxin 2 by Carvalho, Larissa A.C., Truzzi, Daniela R., Fallani, Thamiris S., Alves, Simone V., Toledo, José Carlos, Augusto, Ohara, Netto, Luís E.S., Meotti, Flavia C.

“…Urate hydroperoxide is a product of the oxidation of uric acid by inflammatory heme peroxidases. The formation of urate hydroperoxide might be a key event in…”
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The labile iron pool attenuates peroxynitrite-dependent damage and can no longer be considered solely a pro-oxidative cellular iron source by Damasceno, Fernando Cruvinel, Condeles, André Luis, Lopes, Angélica Kodama Bueno, Facci, Rômulo Rodrigues, Linares, Edlaine, Truzzi, Daniela Ramos, Augusto, Ohara, Toledo, José Carlos

“…The ubiquitous cellular labile iron pool (LIP) is often associated with the production of the highly reactive hydroxyl radical, which forms through a redox…”
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Catalytic Thr or Ser Residue Modulates Structural Switches in 2-Cys Peroxiredoxin by Distinct Mechanisms by Tairum, Carlos A., Santos, Melina Cardoso, Breyer, Carlos A., Geyer, R. Ryan, Nieves, Cecilia J., Portillo-Ledesma, Stephanie, Ferrer-Sueta, Gerardo, Toledo, José Carlos, Toyama, Marcos H., Augusto, Ohara, Netto, Luis E. S., de Oliveira, Marcos A.

“…Typical 2-Cys Peroxiredoxins (2-Cys Prxs) reduce hydroperoxides with extraordinary rates due to an active site composed of a catalytic triad, containing a…”
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Integration mechanisms for different types of innovation: case study in innovative companies by Lizarelli, Fabiane Leticia, de Toledo, Jose Carlos, Alliprandini, Dario Henrique

“…Originality/value--In addition to identifying that integration is possible and occurs in companies, it was possible to verify that the use of integration…”
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Thiol Peroxidases as Major Regulators of Intracellular Levels of Peroxynitrite in Live Saccharomyces cerevisiae Cells by Condeles, André Luís, Gomes, Fernando, de Oliveira, Marcos Antonio, Soares Netto, Luís Eduardo, Toledo Junior, José Carlos

“…Thiol peroxidases (TP) are ubiquitous and abundant antioxidant proteins of the peroxiredoxin and glutathione peroxidase families that can catalytically and…”
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Mechanisms and kinetic profiles of superoxide-stimulated nitrosative processes in cells using a diaminofluorescein probe by Damasceno, Fernando Cruvinel, Facci, Rômulo Rodrigues, da Silva, Thalita Marques, Toledo, José Carlos

“…In this study, we examined the mechanisms and kinetic profiles of intracellular nitrosative processes using diaminofluorescein (DAF-2) as a target in RAW 264.7…”
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Adenanthin Is an Efficient Inhibitor of Peroxiredoxins from Pathogens, Inhibits Bacterial Growth, and Potentiates Antibiotic Activities by dos Santos, Melina Cardoso, Tairum, Carlos Abrunhosa, Cabrera, Vitoria Isabela Montanhero, Guimarães Cauz, Ana Carolina, Ribeiro, Luiz Fernando, Toledo Junior, José Carlos, Toyama, Marcos Hikari, Lago, João Henrique Ghilardi, Brocchi, Marcelo, Netto, Luis Eduardo Soares, de Oliveira, Marcos Antonio

“…The emergence and re-emergence of bacterial strains resistant to multiple drugs represent a global health threat, and the search for novel biological targets…”
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Connecting the Chemical and Biological Properties of Nitric Oxide by Toledo, Jose Carlos, Augusto, Ohara

“…Nitric oxide (NO•; nitrogen monoxide) is known to be a critical regulator of cell and tissue function through mechanisms that utilize its unique…”
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Statistical thinking and its impact on operational performance in manufacturing companies: an empirical study by Lizarelli, Fabiane Letícia, Antony, Jiju, Toledo, José Carlos

“…Statistical thinking (ST) is a concept that has been discussed in the literature as principles and concepts disseminated in companies to conduct a statistical…”
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Input-output-outcome innovation model: an analysis of the Brazilian manufacturing companies by Lizarelli, Fabiane Letícia, Ishizaka, Artur Yuiti, Toledo, José Carlos de

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Six sigma project generation and selection: an action research study by Condé, Giovanni Cláudio Pinto, Toledo, José Carlos, Martens, Mauro Luiz

“…Purpose The purpose of this paper is to test and develop a method for generation and selection of six sigma projects. This is done by testing the use of the…”
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Critical success factors for implementation of an incident learning system in radiation oncology department by Radicchi, Lucas Augusto, Toledo, José Carlos de, Alliprandini, Dário Henrique

“…The aim of this study was to analyze critical success factors (CSFs) for implementation of an incident learning system (ILS) in a radiation oncology department…”
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Aplicação da abordagem lean no processo de desenvolvimento de produto: um survey em empresas industriais brasileiras by Larissa Maria Prisco Pinheiro, José Carlos de Toledo

“…Resumo De acordo com a literatura da área, os princípios enxutos não devem somente ser aplicados na manufatura, mas também se estender para outros processos,…”
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Identificação de relações entre Melhoria Contínua e Inovação de produtos e processos por meio de revisão bibliográfica sistemática by Fabiane Letícia Lizarelli, José Carlos de Toledo

“…A Melhoria Contínua (MC) e a Inovação de produtos e processos são estratégias que geram vantagem competitiva para as organizações, seja em relação ao custo ou…”
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Influence of new product development best practices on performance: an analysis in innovative Brazilian companies by Araujo, Tiago Ribeiro de, Jugend, Daniel, Pimenta, Marcio Lopes, Jesus, Gessica Mina Kim, Barriga, Gladys Dorotea Dorotea Cacsire, Toledo, José Carlos de, Mariano, Ari Melo

“…Purpose This study aims to propose and test a research framework for analyzing the relationship between new product development (NPD) best practices and…”
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The Fuzzy Front End of New Product Development for Brazilian Technology-Based Companies in the Medical Device Industry: a Causal Model by Glauco H.S. Mendes, José Carlos de Toledo

“…The Fuzzy Front End (FFE) is considered the first stage of New Product Development (NPD). The fuzzy front end decisions have great impact on product quality,…”
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