Search Results - "Toledo, Jorge R"

The Hitchhiker's Guide to Human Therapeutic Nanoparticle Development by Ramos, Thelvia I, Villacis-Aguirre, Carlos A, López-Aguilar, Katherine V, Santiago Padilla, Leandro, Altamirano, Claudia, Toledo, Jorge R, Santiago Vispo, Nelson

“…Nanomedicine plays an essential role in developing new therapies through novel drug delivery systems, diagnostic and imaging systems, vaccine development,…”
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Chitosan Microparticles Enhance the Intestinal Release and Immune Response of an Immune Stimulant Peptide in Oncorhynchus mykiss by González-Chavarría, Iván, Roa, Francisco J., Sandoval, Felipe, Muñoz-Flores, Carolina, Kappes, Tomas, Acosta, Jannel, Bertinat, Romina, Altamirano, Claudia, Valenzuela, Ariel, Sánchez, Oliberto, Fernández, Katherina, Toledo, Jorge R.

“…The aquaculture industry is constantly increasing its fish production to provide enough products to maintain fish consumption worldwide. However, the increased…”
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New insight into the biological activity of Salmo salar NK-lysin antimicrobial peptides by Ortega, Leonardo, Carrera, Crisleri, Muñoz-Flores, Carolina, Salazar, Santiago, Villegas, Milton F, Starck, María F, Valenzuela, Ariel, Agurto, Niza, Montesino, Raquel, Astuya, Allisson, Parra, Natalie, Pérez, Ercilia T, Santibáñez, Natacha, Romero, Alex, Ruíz, Pamela, Lamazares, Emilio, Reyes, Fátima, Sánchez, Oliberto, Toledo, Jorge R, Acosta, Jannel

“…NK-lysin is a potent antimicrobial peptide (AMP) with antimicrobial activity against bacteria, fungi, viruses, and parasites. NK-lysin is a type of granulysin,…”
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First report of bovine viral diarrhea virus subgenotypes 1d and 1e in southern Chile by Hugues, Florence, Cabezas, Ignacio, Garigliany, Mutien, Rivas, Felipe, Casanova, Tomás, González, Eddy E, Sánchez, Oliberto, Castillo, Raúl, Parra, Natalie C, Inostroza-Michael, Oscar, Moreno, Lucila, Hernández, Cristián E, Toledo, Jorge R

“…Abstract Bovine viral diarrhea virus (BVDV) affects cattle worldwide causing severe productive and economic loss. In this study, we investigated the…”
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Lectin-like oxidized LDL receptor-1 is an enhancer of tumor angiogenesis in human prostate cancer cells by González-Chavarría, Iván, Cerro, Rita P, Parra, Natalie P, Sandoval, Felipe A, Zuñiga, Felipe A, Omazábal, Valeska A, Lamperti, Liliana I, Jiménez, Silvana P, Fernandez, Edelmira A, Gutiérrez, Nicolas A, Rodriguez, Federico S, Onate, Sergio A, Sánchez, Oliberto, Vera, Juan C, Toledo, Jorge R

“…Altered expression and function of lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) has been associated with several diseases such as…”
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New Formulation of a Subunit Vaccine Candidate against Lawsonia intracellularis Increases Humoral and Cellular Immune Responses by Salazar, Santiago, Starck, María Francisca, Villegas, Milton F, Acosta, Jannel, Sánchez, Oliberto, Ramos, Eduardo, Nova-Lamperti, Estefanía, Toledo, Jorge R, Gädicke, Paula, Ruiz, Álvaro, González, Alaín, Montesino, Raquel

“…Previously, we designed a subunit vaccine candidate based on three antigens with promising results in pigs. In this study, antigens were produced individually…”
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Co-Formulation of Recombinant Porcine IL-18 Enhances the Onset of Immune Response in a New Lawsonia intracellularis Vaccine by Hidalgo-Gajardo, Angela, Gutiérrez, Nicolás, Lamazares, Emilio, Espinoza, Felipe, Escobar-Riquelme, Fernanda, Leiva, María J, Villavicencio, Carla, Mena-Ulecia, Karel, Montesino, Raquel, Altamirano, Claudia, Sánchez, Oliberto, Rivas, Coralia I, Ruíz, Álvaro, Toledo, Jorge R

“…Pig is one of the most consumed meats worldwide. One of the main conditions for pig production is Porcine Enteropathy caused by . Among the effects of this…”
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Immunomodulatory role of vasoactive intestinal peptide and ghrelin in Oncorhynchus mykiss by Muñoz-Flores, Carolina, Roa, Francisco J., Saavedra, Paulina, Fuentealba, Pablo, Starck, María F., Ortega, Leonardo, Montesino, Raquel, Valenzuela, Ariel, Astuya, Allisson, Parra, Natalie, González-Chavarría, Iván, Sánchez, Oliberto, Toledo, Jorge R., Acosta, Jannel

“…Neuropeptides are a group of peptides derived from precursor proteins synthesized in neuronal and nonneuronal cells. The classical functions of neuropeptides…”
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Conformational and thermal stability improvements for the large-scale production of yeast-derived rabbit hemorrhagic disease virus-like particles as multipurpose vaccine by Fernández, Erlinda, Toledo, Jorge R, Méndez, Lídice, González, Nemecio, Parra, Francisco, Martín-Alonso, José M, Limonta, Miladys, Sánchez, Kosara, Cabrales, Ania, Estrada, Mario P, Rodríguez-Mallón, Alina, Farnós, Omar

“…Recombinant virus-like particles (VLP) antigenically similar to rabbit hemorrhagic disease virus (RHDV) were recently expressed at high levels inside Pichia…”
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Isolation, characterization, and immunomodulatory activity evaluation of probiotic strains from colostrum and canine milk by Quilodrán-Vega, Sandra Rayén, Muñoz-Flores, Carolina, Pino, Ana, Buldres, Paula, Sandoval, Felipe, Aguirre, Alex, Portillo, Brígida, Parra, Natalie, Altamirano, Claudia, Albarracín, Leonardo, Villena, Julio, Toledo, Jorge R

“…This study aimed to characterize potential probiotic strains for use in dogs to prevent infectious enteropathies. Lactic acid bacteria (LAB) isolated from…”
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A Heterologous Viral Protein Scaffold for Chimeric Antigen Design: An Example PCV2 Virus Vaccine Candidate by Lamazares, Emilio, Gutiérrez, Fernando, Hidalgo, Angela, Gutiérrez, Nicolas A, Espinoza, Felipe I, Sánchez, Oliberto, Cortez-San Martín, Marcelo, Mascayano, Carolina, González, Javier, Saavedra, José, Altamirano, Claudia, Mansur, Manuel, Ruiz, Álvaro, Toledo, Jorge R

“…Recombinant vaccines have low-cost manufacturing, regulatory requirements, and reduced side effects compared to attenuated or inactivated vaccines. In the…”
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Maytenus disticha Extract and an Isolated β-Dihydroagarofuran Induce Mitochondrial Depolarization and Apoptosis in Human Cancer Cells by Increasing Mitochondrial Reactive Oxygen Species by González-Chavarría, Iván, Duprat, Felix, Roa, Francisco J, Jara, Nery, Toledo, Jorge R, Miranda, Felipe, Becerra, José, Inostroza, Alejandro, Kelling, Alexandra, Schilde, Uwe, Heydenreich, Matthias, Paz, Cristian

“…(Hook F.), belonging to the Celastraceae family, is an evergreen shrub, native of the central southern mountains of Chile. Previous studies demonstrated that…”
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In vitro immunomodulatory activities of peptides derived from Salmo salar NK-lysin and cathelicidin in fish cells by Acosta, Jannel, Roa, Francisco, González-Chavarría, Iván, Astuya, Allison, Maura, Rafael, Montesino, Raquel, Muñoz, Carolina, Camacho, Frank, Saavedra, Paulina, Valenzuela, Ariel, Sánchez, Oliberto, Toledo, Jorge R.

“…Antimicrobial peptides (AMPs) are amphipathic peptides, which play an important role in innate defence. These peptides are gene-encoded and either…”
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Salmonid MyD88 is a key adapter protein that activates innate effector mechanisms through the TLR5M/TLR5S signaling pathway and protects against Piscirickettsia salmonis infection by Muñoz-Flores, Carolina, Astuya-Villalón, Allisson, Romero, Alex, Acosta, Jannel, Toledo, Jorge R.

“…The membrane-anchored and soluble Toll-like Receptor 5 -TLR5M and TLR5S, respectively-from teleost recognize bacterial flagellin and induce the…”
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Raman spectroscopy and silver nanoparticles for efficient detection of membrane proteins in living cells by Fleitas-Salazar, Noralvis, Pedroso-Santana, Seidy, Silva-Campa, Erika, Angulo-Molina, Aracely, Toledo, Jorge R, Riera, Raul, Pedroza-Montero, Martin

“…Molecular fingerprints revealed by Raman techniques show great potential for biomedical applications, like disease diagnostic through Raman detection of tumor…”
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Agonistic effect of peptides derived from a truncated HMGB1 acidic tail sequence in TLR5 from Salmo salar by Vásquez-Suárez, Aleikar, Ortega, Leonardo, González-Chavarría, Iván, Valenzuela, Ariel, Muñoz-Flores, Carolina, Altamirano, Claudia, Acosta, Jannel, Toledo, Jorge R

“…Based on the structural knowledge of TLR5 surface and using blind docking platforms, peptides derived from a truncated HMGB1 acidic tail from Salmo salar was…”
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High expression level of recombinant human erythropoietin in the milk of non-transgenic goats by Toledo, Jorge R., Sánchez, Oliberto, Seguí, Raquel Montesino, García, Gerardo, Montañez, Margela, Zamora, Pastor A., Rodríguez, María P., Cremata, José A.

“…The high degree of structural conservation of erythropoietin between species, make it, especially, difficult to produce this protein growth factor in the milk…”
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Design and characterization of a novel dimeric blood–brain barrier penetrating TNFα inhibitor by Manrique‐Suárez, Viana, Macaya, Luis, Contreras, Maria Angélica, Parra, Natalie, Maura, Rafael, González, Alaín, Toledo, Jorge R., Sánchez, Oliberto

“…Tumor necrosis factor‐alpha (TNFα) inhibitors could prevent neurological disorders systemically, but their design generally relies on molecules unable to cross…”
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Development and characterization of a novel variant of long-acting bovine follicle-stimulating hormone (brscFSH) by Cabeza, Oscar Ignacio, Parra, Natalie, Cerro, Rita, Mansilla, Rodrigo, Sanchez, Roxana Zuniga, Gutierrez-Reinoso, Miguel, Escribano, Eduardo H., Castillo, Raul, Rodriguez-Alvarez, Lleretny, Tavares, Kaio, Gaudencio, Saul, Martins, Leonardo, Hugues, Florence I., Acosta, Jannel, Moreno, Ernesto, Montesino, Raquel, García-Herreros, Manuel, Casanova, Frank Camacho, Toledo, Jorge R., Sanchez, Oliberto

“…Assisted reproduction is a key aspect of modern animal breeding, providing valuable assistance in improving breeding programs. In this field, the…”
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A trivalent TNF‐R2 as a new tumor necrosis factor alpha‐blocking molecule by Contreras, María A., Macaya, Luis, Manrique, Viana, Camacho, Frank, González, Alain, Montesinos, Raquel, Toledo, Jorge R., Sánchez, Oliberto

“…The neutralization of tumor necrosis factor alpha (TNFα) with biopharmaceuticals is a successful therapy for inflammatory diseases. Currently, one of the main…”
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