Search Results - "Toledo, F. G. S."

Effects of weight loss and exercise on insulin resistance, and intramyocellular triacylglycerol, diacylglycerol and ceramide by Dubé, J. J., Amati, F., Toledo, F. G. S., Stefanovic-Racic, M., Rossi, A., Coen, P., Goodpaster, B. H.

“…Aims/hypothesis Intramyocellular lipids, including diacylglycerol (DAG) and ceramides, have been linked to insulin resistance. This randomised…”
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First-in-human phase I study of copanlisib (BAY 80-6946), an intravenous pan-class I phosphatidylinositol 3-kinase inhibitor, in patients with advanced solid tumors and non-Hodgkin's lymphomas by Patnaik, A., Appleman, L.J., Tolcher, A.W., Papadopoulos, K.P., Beeram, M., Rasco, D.W., Weiss, G.J., Sachdev, J.C., Chadha, M., Fulk, M., Ejadi, S., Mountz, J.M., Lotze, M.T., Toledo, F.G.S., Chu, E., Jeffers, M., Peña, C., Xia, C., Reif, S., Genvresse, I., Ramanathan, R.K.

“…To evaluate the safety, tolerability, pharmacokinetics, and maximum tolerated dose (MTD) of copanlisib, a phosphatidylinositol 3-kinase inhibitor, in patients…”
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Reduced skeletal muscle oxidative capacity and elevated ceramide but not diacylglycerol content in severe obesity by Coen, P.M., Hames, K.C., Leachman, E.M., DeLany, J.P., Ritov, V.B., Menshikova, E.V., Dubé, J.J., Stefanovic‐Racic, M., Toledo, F.G.S., Goodpaster, B.H.

“…Objective The link between a reduced capacity for skeletal muscle mitochondrial fatty acid oxidation (FAO) and lipotoxicity in human insulin resistance has…”
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ADP-Ribosyl Cyclase in Rat Vascular Smooth Muscle Cells : Properties and Regulation by de Toledo, Frederico G. S, Cheng, Jingfei, Liang, Mingyu, Chini, Eduardo N, Dousa, Thomas P

“…We investigated whether ADP-ribosyl cyclase (ADPR-cyclase) in rat vascular smooth muscle cells (VSMCs) has enzymatic properties that differ from the…”
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γ-L-glutamyl-L-DOPA inhibits Na+-phosphate cotransport across renal brush border membranes and increases renal excretion of phosphate by De Toledo, Frederico G.S., Thompson, Michael A., Bolliger, Chad, Tyce, Gertrude M., Dousa, Thomas P.

“…γ-L-glutamyl-L-DOPA inhibits Na+-phosphate cotransport across renal brush border membranes and increases renal excretion of phosphate. For treatment of…”
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Opposite paracrine effects of 5-HT and dopamine on Na+-Pi cotransport in opossum kidney cells by De Toledo, Frederico G.S., Beers, Kelly W., Berndt, Theresa J., Thompson, Michael A., Tyce, Gertrude M., Knox, Franklyn G., Dousa, Thomas P.

“…Opposite paracrine effects of 5-HT and dopamine on Na+-Pi cotransport in opossum kidney cells. Serotonin (5-HT) was recently reported to inhibit cAMP…”
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The Ca2+-transporting ATPases of rabbit and trout exhibit different pH- and temperature-dependences by CHINI, E. N, DE TOLEDO, F. G. S, ALBUQUERQUE, M. C, DE MEIS, L

“…The phosphorylation of the trout sarcoplasmic-reticulum Ca(2+)-ATPase by Pi differs in its temperature- and pH-dependence from the rabbit ATPase. In the trout…”
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