Search Results - "Tolbert, Caitlin E"
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Tension on JAM-A activates RhoA via GEF-H1 and p115 RhoGEF
Published in Molecular biology of the cell (01-05-2016)“…Junctional adhesion molecule A (JAM-A) is a broadly expressed adhesion molecule that regulates cell-cell contacts and facilitates leukocyte transendothelial…”
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N-glycosylation controls the function of junctional adhesion molecule-A
Published in Molecular biology of the cell (15-09-2015)“…Junctional adhesion molecule-A (JAM-A) is an adherens and tight junction protein expressed by endothelial and epithelial cells. JAM-A serves many roles and…”
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3
Identification of an Actin Binding Surface on Vinculin that Mediates Mechanical Cell and Focal Adhesion Properties
Published in Structure (London) (06-05-2014)“…Vinculin, a cytoskeletal scaffold protein essential for embryogenesis and cardiovascular function, localizes to focal adhesions and adherens junctions,…”
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The Vinculin C-terminal Hairpin Mediates F-actin Bundle Formation, Focal Adhesion, and Cell Mechanical Properties
Published in The Journal of biological chemistry (30-12-2011)“…Vinculin is an essential and highly conserved cell adhesion protein, found at both focal adhesions and adherens junctions, where it couples integrins or…”
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5
Loss of ATM positively regulates Rac1 activity and cellular migration through oxidative stress
Published in Biochemical and biophysical research communications (22-01-2019)“…Ataxia-telangiectasia mutated (ATM) is a serine-threonine kinase that is integral in the response to DNA double-stranded breaks (DSBs). Cells and tissues…”
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6
Vinculin and metavinculin: Oligomerization and interactions with F-actin
Published in FEBS letters (17-04-2013)“…Vinculin, and its splice variant metavinculin, are scaffolding proteins that localize to cellular adhesions. Vinculin is a key player in mediating cell…”
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A Structural Model for Vinculin Insertion into PIP2-Containing Membranes and the Effect of Insertion on Vinculin Activation and Localization
Published in Structure (London) (07-02-2017)“…Vinculin, a scaffolding protein that localizes to focal adhesions (FAs) and adherens junctions, links the actin cytoskeleton to the adhesive super-structure…”
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Phosphorylation at Y1065 in Vinculin Mediates Actin Bundling, Cell Spreading, and Mechanical Responses to Force
Published in Biochemistry (Easton) (02-09-2014)“…Vinculin is an essential structural adaptor protein that localizes to sites of adhesion and is involved in a number of cell processes including adhesion,…”
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Vinculin regulation of F-actin bundle formation: What does it mean for the cell?
Published in Cell adhesion & migration (01-03-2013)“…Vinculin is an essential cell adhesion protein, found at both focal adhesions and adherens junctions, where it couples transmembrane proteins to the actin…”
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Correction to Phosphorylation at Y1065 in Vinculin Mediates Actin Bundling, Cell Spreading, and Mechanical Responses to Force
Published in Biochemistry (Easton) (07-10-2014)Get full text
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Gα12 structural determinants of Hsp90 interaction are necessary for serum response element-mediated transcriptional activation
Published in Molecular pharmacology (01-04-2014)“…The G12/13 class of heterotrimeric G proteins, comprising the α-subunits Gα12 and Gα13, regulates multiple aspects of cellular behavior, including…”
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12
Loss of ATM Positively Regulates Rac1 Activity and Cellular Migration Through Oxidative Stress
Published in The FASEB journal (01-04-2019)“…Ataxia‐telangiectasia mutated (ATM) is a serine‐threonine kinase that is integral in the response to DNA double‐stranded breaks (DSBs). Cells and tissues…”
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13
Role of PIP2-Dependent Membrane Interactions in Vinculin Activation, Motility and Force Transmission
Published in Biophysical journal (16-02-2016)Get full text
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14
Identification of a new actin binding surface on vinculin that mediates mechanical cell and focal adhesion properties
Published in Structure (London) (27-03-2014)“…Vinculin, a cytoskeletal scaffold protein essential for embryogenesis and cardiovascular function, localizes to focal adhesions and adherens junctions,…”
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15
A Structural Model for Vinculin Insertion into PIP 2 -Containing Membranes and the Effect of Insertion on Vinculin Activation and Localization
Published in Structure (London) (07-02-2017)“…Vinculin, a scaffolding protein that localizes to focal adhesions (FAs) and adherens junctions, links the actin cytoskeleton to the adhesive super-structure…”
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