Search Results - "Tokutake, Y"
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Administration of platelet concentrates suspended in bicarbonated Ringer's solution in children who had platelet transfusion reactions
Published in Vox sanguinis (01-02-2018)“…Background and Objectives Adverse reactions to platelet transfusions are a problem. Children with primary haematological and malignant diseases may experience…”
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Proliferating bovine intramuscular preadipocyte cells synthesize leptin
Published in Domestic animal endocrinology (01-07-2013)“…Leptin is thought to be not only a satiety factor but also a stimulator of angiogenesis. We examined leptin, PPARγ2, and vascular endothelial growth factor…”
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A unique human gene that spans over 230 kb in the human chromosome 8p11-12 and codes multiple family proteins sharing RNA-binding motifs
Published in Proceedings of the National Academy of Sciences - PNAS (01-10-1996)“…A unique gene, RBP-MS, spanning over 230 kb in the human chromosome 8p11-12 near the Werner syndrome gene locus is described. The single-copy RBP-MS gene is…”
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Forces for Morphogenesis Investigated with Laser Microsurgery and Quantitative Modeling
Published in Science (American Association for the Advancement of Science) (04-04-2003)“…We investigated the forces that connect the genetic program of development to morphogenesis in Drosophila. We focused on dorsal closure, a powerful model…”
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HLA DRB10405-DQB10401 haplotype is associated with autoimmune pancreatitis in the japanese population
Published in Gastroenterology (New York, N.Y. 1943) (01-05-2002)“…Autoimmune pancreatitis is a distinctive disease entity characterized by high serum immunoglobulin G4 concentrations. Because of the close association between…”
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Efficient Bump-Pad Geometries to Relax Design Rules Required for High Density I/O Area Array Packaging
Published in IEEE transactions on advanced packaging (01-02-2009)“…Continuous increase in density of interconnection is demanded as a result of advances in the performance of electronic devices. Because a finer design rule is…”
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Severe growth defect in mouse cells lacking the telomerase RNA component
Published in Nature genetics (01-06-1998)“…The ribonucleoprotein enzyme telomerase synthesizes telomeric DNA onto chromosome ends. Telomere length is maintained, by the presence of telomerase activity,…”
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Detection by Epitope-Defined Monoclonal Antibodies of Werner DNA Helicases in the Nucleoplasm and Their Upregulation by Cell Transformation and Immortalization
Published in The Journal of cell biology (11-01-1999)“…We prepared several monoclonal antibodies (mAbs) specific for the NH2- and COOH-terminal regions of the DNA helicase (WRN helicase) responsible for Werner's…”
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Extra-Chromosomal Telomere Repeat DNA in Telomerase-Negative Immortalized Cell Lines
Published in Biochemical and biophysical research communications (29-06-1998)“…We found novel extra-chromosomal telomere repeat (ECTR) DNAs in telomerase-negative immortalized KMST-6 cells, by staining these cells with a (TTAGGG) nprobe…”
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Abnormal telomere dynamics of B-lymphoblastoid cell strains from Werner's syndrome patients transformed by Epstein-Barr virus
Published in Oncogene (16-10-1997)“…The characteristics of B-lymphoblastoid cell strains transformed by Epstein-Barr virus (EBV) from normal individuals and Werner's syndrome (WRN) patients were…”
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Mutation and haplotype analyses of the Werner's syndrome gene based on its genomic structure : genetic epidemiology in the Japanese population
Published in Human genetics (01-07-1997)“…The correlation between mutations in the Werner's syndrome (WRN) gene and the haplotypes of surrounding markers was studied in Japanese patients. We have…”
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Telomere repeat DNA forms a large non-covalent complex with unique cohesive properties which is dissociated by Werner syndrome DNA helicase in the presence of replication protein A
Published in Nucleic acids research (15-09-2000)“…We describe the unique structural features of a large telomere repeat DNA complex (TRDC) of >20 kb generated by a simple PCR using (TTAGGG)(4) and (CCCTAA)(4)…”
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Multiple POU-binding motifs, recognized by tissue-specific nuclear factors, are important for Dll1 gene expression in neural stem cells
Published in Biochemical and biophysical research communications (17-12-2004)“…We cloned the 5′-flanking region of the mouse homolog of the Delta gene (Dll1) and demonstrated that the sequence between nucleotide position −514 and −484 in…”
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Analysis of helicase gene mutations in Japanese Werner's syndrome patients
Published in Human genetics (01-02-1997)“…The profile of helicase gene mutations was studied in 89 Japanese Werner's syndrome (WRN) patients by examining the previously described mutations 1-4 as well…”
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Human Stanniocalcin (STC): Genomic Structure, Chromosomal Localization, and the Presence of CAG Trinucleotide Repeats
Published in Genomics (San Diego, Calif.) (01-02-1998)“…Stanniocalcin (STC) is a glycoprotein hormone that is secreted by the corpuscle of Stannius, an endocrine gland of bony fish. It prevents hypercalcemia via…”
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Antitumor effects of a novel monoclonal antibody with high binding affinity to ganglioside GD3
Published in Cancer Immunology Immunotherapy (01-07-1993)“…Ganglioside GD3, which is one of the major gangliosides expressed on the cell surface human tumors of neuroectodermal origin, has been studied as a target…”
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In vitro antiviral activity of polyoxomolybdates. Mechanism of inhibitory effect of PM-104 (NH4)12H2(Eu4(MoO4)(H2O)16(Mo7O24)4).13H2O on human immunodeficiency virus type 1
Published in Antiviral research (01-04-1993)“…A screening for inhibitors of human immunodeficiency virus type 1 (HIV-1) among various types of isopolyoxomolybdates and heteropolyoxomolybdates was carried…”
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Antiviral activity of polyoxomolybdoeuropate PM-104 against human immunodeficiency virus type 1
Published in Chemical & pharmaceutical bulletin (01-06-1991)“…A polyoxomolybdoeuropate PM-104 (NH4)12H2[Eu4(MoO4)(H2O)16(Mo7O24)4].13H2O was found to be a potent inhibitor of the growth of human immunodeficiency virus…”
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A mouse/human chimeric anti-(ganglioside GD3) antibody with enhanced antitumor activities
Published in Cancer Immunology Immunotherapy (01-11-1993)“…Ganglioside GD3, which is one of the major gangliosides expressed on the cell surface of human tumors of neuroectodermal origin has been focused on as a target…”
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Cloning and Characterization of Rep-8 (D8S2298E) in the Human Chromosome 8p11.2–p12
Published in Genomics (San Diego, Calif.) (15-01-1997)“…A novel human gene referred to as the Rep-8 gene (D8S2298E) was cloned by a combination of exon trapping, thermal asymmetric interlaced-PCR, and screening of a…”
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