Search Results - "Tokumaru, Hiroshi"

Distinct initial SNARE configurations underlying the diversity of exocytosis by Kasai, Haruo, Takahashi, Noriko, Tokumaru, Hiroshi

“…The dynamics of exocytosis are diverse and have been optimized for the functions of synapses and a wide variety of cell types. For example, the kinetics of…”
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Effects of Phenolic Acids Produced from Food-Derived Flavonoids and Amino Acids by the Gut Microbiota on Health and Disease by Kiriyama, Yoshimitsu, Tokumaru, Hiroshi, Sadamoto, Hisayo, Kobayashi, Suguru, Nochi, Hiromi

“…The gut microbiota metabolizes flavonoids, amino acids, dietary fiber, and other components of foods to produce a variety of gut microbiota-derived…”
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Identification and classification of innexin gene transcripts in the central nervous system of the terrestrial slug Limax valentianus by Sadamoto, Hisayo, Takahashi, Hironobu, Kobayashi, Suguru, Kondoh, Hirooki, Tokumaru, Hiroshi

“…Intercellular gap junction channels and single-membrane channels have been reported to regulate electrical synapse and the brain function. Innexin is known as…”
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Buchwald–Hartwig Amination of Phosphinines and the Effect of Amine Substituents on Optoelectronic Properties of the Resulting Coupling Products by Nagahora, Noriyoshi, Goto, Shoko, Inatomi, Takahiro, Tokumaru, Hiroshi, Matsubara, Kouki, Shioji, Kosei, Okuma, Kentaro

“…The Buchwald–Hartwig amination of a phosphinine bearing a bromophenyl moiety was carried out using a dinuclear Ni catalyst. A variety of monoarylamines,…”
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Synthetic studies on a series of functionalized pyrylium salts, 4-chloro- and 4-bromophosphinines by Nagahora, Noriyoshi, Tokumaru, Hiroshi, Ikaga, Shinpei, Hanada, Takuya, Shioji, Kosei, Okuma, Kentaro

“…A series of new pyrylium salts that bear sulfonate and phosphonate groups were obtained from the reactions between 2,6-diphenyl-4H-pyran-4-one, sulfonic…”
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Syntheses, Structures, and Properties of Biphosphinines Tethered Aromatic π-System by Nagahora, Noriyoshi, Ogawa, Tamaki, Honda, Maki, Fujii, Motomi, Tokumaru, Hiroshi, Sasamori, Takahiro, Shioji, Kosei, Okuma, Kentaro

“…The syntheses of a series of biphosphinine derivatives inserted an aromatic π-spacer have been achieved. Their absorption, emission properties, and…”
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SNARE Complex Oligomerization by Synaphin/Complexin Is Essential for Synaptic Vesicle Exocytosis by Tokumaru, Hiroshi, Umayahara, Keiko, Pellegrini, Lorenzo L, Ishizuka, Toru, Saisu, Hideo, Betz, Heinrich, Augustine, George J, Abe, Teruo

“…Synaphin/complexin is a cytosolic protein that preferentially binds to syntaxin within the SNARE complex. We find that synaphin promotes SNAREs to form…”
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Synaphin/complexin recruits calcium sensor synaptotagmin 1 to the SNARE-driven fusion machinery for synaptic vesicle exocytosis by Tokumaru, Hiroshi, Shimizu-Okabe, Chigusa, Shinohara, Takumi, Abe, Teruo

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Proteins involved in synaptic vesicle trafficking by Augustine, George J., Burns, Marie E., DeBello, William M., Hilfiker, Sabine, Morgan, Jennifer R., Schweizer, Felix E., Tokumaru, Hiroshi, Umayahara, Keiko

“…Neurotransmitter release relies on a series of synaptic vesicle trafficking reactions. We have determined the molecular basis of these reactions by…”
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Two-photon fluorescence lifetime imaging of primed SNARE complexes in presynaptic terminals and β cells by Takahashi, Noriko, Sawada, Wakako, Noguchi, Jun, Watanabe, Satoshi, Ucar, Hasan, Hayashi-Takagi, Akiko, Yagishita, Sho, Ohno, Mitsuyo, Tokumaru, Hiroshi, Kasai, Haruo

“…It remains unclear how readiness for Ca 2+ -dependent exocytosis depends on varying degrees of SNARE complex assembly. Here we directly investigate the SNARE…”
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A self-oscillation-type ultrasonic linear actuator by TODA, K, TOKUMARU, H

“…A cylindrical piezoelectric ceramic vibrator with two half-moon-shaped electrodes on a flat surface is described as a key device for constructing a linear…”
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Syntheses, Structures, and Properties of Biphosphinines Tethered Aromatic [pi]-System by Nagahora, Noriyoshi, Ogawa, Tamaki, Honda, Maki, Fujii, Motomi, Tokumaru, Hiroshi, Sasamori, Takahiro, Shioji, Kosei, Okuma, Kentaro

“…The syntheses of a series of biphosphinine derivatives inserted an aromatic [pi]-spacer have been achieved. Their absorption, emission properties, and…”
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Involvement of calciseptine-Sensitive Calcium Channels in the Evoked Acetylcholine Release from Electric Organ Synaptosomes by TOKUMARU, Hiroshi, SATOH, Yasushi, HIRASHIMA, Naohide, SHOJAKU, Suzuyo, YAMAMOTO, Haruhiko, KIRINO, Yutaka

“…The high K+ -evoked release of acetylcholine (ACh) from electric organ synaptosomes isolated from the Japanese marine ray, Narke japonica, was strongly…”
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Lambert-Eaton syndrome antibodies inhibit acetylcholine release and P/Q-type Ca2+ channels in electric ray nerve endings by Satoh, Yasushi, Hirashima, Naohide, Tokumaru, Hiroshi, Takahashi, Masanori P., Ang, Jin K, Viglione, Michael P., Kim, Yong I., Kirino, Yutaka

“…The types of voltage-dependent calcium channels (VDCCs) present in the cholinergic terminals isolated from the electric organ of the ray, Narke japonica , were…”
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Synaptotagmin 1 binding to the carboxyl terminal region of synaphin/complexin is important for vesicle exocytosis by Shimizu-Okabe, Chigusa, Shinohara, Takumi, Tsuboi, Takashi, Abe, Teruo, Tokumaru, Hiroshi

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Direct interaction of SNARE complex binding protein synaphin/complexin with calcium sensor synaptotagmin 1 by Tokumaru, Hiroshi, Shimizu-Okabe, Chigusa, Abe, Teruo

“…Although the binding of synaphin (also called complexin) to the soluble N -ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complex is…”
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Two-photon fluorescence lifetime imaging of primed SNARE complexes in presynaptic terminals and [beta] cells by Takahashi, Noriko, Sawada, Wakako, Noguchi, Jun, Watanabe, Satoshi, Ucar, Hasan, Hayashi-takagi, Akiko, Yagishita, Sho, Ohno, Mitsuyo, Tokumaru, Hiroshi, Kasai, Haruo

“…It remains unclear how readiness for Ca2+ -dependent exocytosis depends on varying degrees of SNARE complex assembly. Here we directly investigate the SNARE…”
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Timing of synaphin/complexin binding to SNARE complex was probed by caged binding-site peptide by Hiroshi Tokumaru, George Augustine, Norio Shimamoto

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UNC-13 and neurotransmitter release by Tokumaru, Hiroshi, Augustine, George J

“…Genetic studies in mice, worms and flies indicate that the synaptic protein UNC-13 plays a central role in the regulation of vesicle fusion…”
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Activation of adenosine A1 and A2 receptors differentially affects acetylcholine release from electric organ synaptosomes by modulating calcium channels by Satoh, Yasushi, Hirashima, Naohide, Tokumaru, Hiroshi, Kirino, Yutaka

“…Adenosine inhibited the release of acetylcholine (ACh) evoked by high K + depolarization from synaptosomes isolated from the electric organ of the Japanese…”
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