Search Results - "Tokgün, Onur"

Diagnostic difficulty in a patient with recurrent attacks of acute polyneuropathy: Acute intermittent porphyria by Tekin,Selma, Karagülmez,Ahmet Mağrur, Erdoğan,Çağdaş, Değirmenci,Eylem, Tokgün,Onur

“…Acute intermittent porphyria is one of the most common porphyria subtypes. There is a critical need to diagnose porphyria, given its multisystem nature and the…”
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Myc manipulates the miRNA content and biologic functions of small cell lung cancer cell-derived small extracellular vesicles by Tokgün, Onur, İnci, Kubilay

“…Background MYC genes are amplified/overexpressed in 20% of SCLCs, showing that Myc and Myc-dependent cellular mechanisms are strong candidates as therapeutic…”
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Investigation of diabetes-related molecular changes in embryo-endometrium crosstalk by Tan, Semih, Tan, Seçil, Tokgün, Onur, Çetin, Hülya, Tokgün, Elvan, Özdamar, Saim

“…•Diabetes causes MMP and TIMP expression changes.•Diabetes affects maintenance of pregnancy by calcium, BMP, p53, Hippo, Wnt and TNF like signalling…”
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Zinc oxide nanoparticles: Genotoxicity, interactions with UV-light and cell-transforming potential by Demir, Eşref, Akça, Hakan, Kaya, Bülent, Burgucu, Durmuş, Tokgün, Onur, Turna, Fatma, Aksakal, Sezgin, Vales, Gerard, Creus, Amadeu, Marcos, Ricard

“…•Genotoxicity of ZnO NPs has been shown in mammalian cells.•ZnO NPs has been able to induce cell transformation.•An antagonist interaction between ZnO NPs and…”
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Genotoxic and cell-transforming effects of titanium dioxide nanoparticles by Demir, Eşref, Akça, Hakan, Turna, Fatma, Aksakal, Sezgin, Burgucu, Durmuş, Kaya, Bülent, Tokgün, Onur, Vales, Gerard, Creus, Amadeu, Marcos, Ricard

“…The in vitro genotoxic and the soft-agar anchorage independent cell transformation ability of titanium dioxide nanoparticles (nano-TiO2) and its…”
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Growth suppression by MYC inhibition in small cell lung cancer cells with TP53 and RB1 inactivation by Fiorentino, Francesco Paolo, Tokgün, Elvan, Solé-Sánchez, Sònia, Giampaolo, Sabrina, Tokgün, Onur, Jauset, Toni, Kohno, Takashi, Perucho, Manuel, Soucek, Laura, Yokota, Jun

“…Small cell lung cancer (SCLC) is the most aggressive type of lung cancer with high mortality. One of the MYC family genes, MYC, MYCL or MYCN, is amplified in…”
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Therapeutic Effect of Teneligliptin in Drug-Induced Nephrotoxicity: An In-Vitro Study by Becerir, Tülay, Tokgün, Onur, İnci, Kubilay, Girişgen, İlknur, Yuksel, Selcuk

“…Background Drug-induced nephrotoxicity is an important side effect of many commonly used drugs. In this study, we planned to evaluate the effects of…”
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Transcriptional profilling to identify the inhibitor effect of trehalose as an alternative natural therapeutic agent on pterygium cells by Yılmaz, Uğur, Durkal, Yasin, Tokgün, Onur, İnci, Kubilay

“…Aims/Purpose: The aim of this study to investigate transcriptome analysis of the inhibitory effects of trehalose on changing expression of regulator genes in…”
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Novel ruthenium and palladium complexes as potential anticancer molecules on SCLC and NSCLC cell lines by Tokgun, Onur, Karakas, Duygu Elma, Tan, Semih, Karagür, Ege Rıza, İnal, Behcet, Akca, Hakan, Durap, Feyyaz, Baysal, Akın, Aydemir, Murat

“…Lung cancer is one of the major causes of cancer-related deaths in the world. Non-small-cell lung cancer (NSCLC) is the most common type of lung cancer, and…”
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Investigation of fructose consumption on hippocampal insulin and glucagon-like peptide-1 receptors, and metabolic effects in rats by Altintas, Fatih, Caliskan, Sadettin, Kilic-Toprak, Emine, Tokgun, Onur, Avci, Neslihan Esra, Vural Kucukatay

“…Objective(s): The detrimental effects of high fructose consumption on metabolic health have been extensively studied. However, limited research has focused on…”
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The impact of hereditary thrombophilias in recurrent pregnancy loss by Karagur, Ege, Alay, Mustafa, Demiray, Aydin, Karagenc, Nedim, Tokgün, Onur, Durak, Taner, Akca, Hakan

“…Introduction: Recurrent pregnancy loss (RPL) is defined as two or more consecutive pregnancy loss which occurs before the 20th weeks of pregnancies for the…”
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Convolvulus galaticus, Crocus antalyensis, and Lilium candidum extracts show their antitumor activity through induction of p53-mediated apoptosis on human breast cancer cell line MCF-7 cells by Tokgun, Onur, Akca, Hakan, Mammadov, Ramazan, Aykurt, Candan, Deniz, Gökhan

“…Conventional and newly emerging treatment procedures such as chemotherapy, catalytic therapy, photodynamic therapy, and radiotherapy have not succeeded in…”
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Triptolide: Regulator of Cellular Metabolism of Significant Fraction of Small Cell Lung Cancer via lncRNAs by Tokgün, Onur, İnci, Kubilay

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The protective effect of docosahexaenoic acid on the bilirubin neurotoxicity by Becerir, Cem, Kılıç, İlknur, Sahin, Özlem, Özdemir, Özmert, Tokgün, Onur, Özdemir, Bülent, Akca, Hakan

“…Usually, all newborns demonstrate high serum unconjugated bilirubin (UCB) level. UCB may induce adverse effects in the central nervous system. We aimed to…”
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DEREGULATED EXPRESSIONS OF MYC ALTER THE EXPRESSIONS OF tRNAS IN BREAST CANCER CELLS by Tokgün, Pervin, Tokgün, Onur

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Protective effect of insulin and glucose at different concentrations on penicillin-induced astrocyte death on the primer astroglial cell line by Mehmet Bülent zdemir Hakan Aka agdas Erdogan Onur Tokgün Aydin Demiray Fenki Semin Cem Becerir

“…Astrocytes perform many functions in the brain and spinal cord.Glucose metabolism is important for astroglial cells and astrocytes are the only cells with…”
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Exosome inhibition improves response to first‐line therapy in small cell lung cancer by Irep, Nesrin, Inci, Kubilay, Tokgun, Pervin Elvan, Tokgun, Onur

“…Exosomes are recognized as important mediators of cell‐to‐cell communication, facilitating carcinogenesis. Although there have been significant advancements in…”
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Correction: An In Vitro Study for the Role of Schizophrenia-Related Potential miRNAs in the Regulation of COMT Gene by Tonk, Onur, Tokgun, Pervin Elvan, Yılmaz, Özge Sarıca, Tokgun, Onur, Inci, Kubilay, Çelikkaya, Büşra, Altintas, Nuray

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MYC-driven regulation of long non-coding RNA profiles in breast cancer cells by Tokgun, Pervin Elvan, Tokgun, Onur, Kurt, Serap, Tomatir, Ayse Gaye, Akca, Hakan

“…MYC deregulation contributes to breast cancer development and progression. Deregulated expression levels of long non-coding RNAs (lncRNA) have been…”
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Integrative analysis of ex vivo studies and microarray reveals the novel inhibitor effects of trehalose on the pathogenesis of pterygium by Durkal, Yasin, İnci, Kubilay, Tokgun, Onur, Yilmaz, Ugur, Yılmaz, Banu Candan

“…Pterygium is a frequent eye surface condition that is characterized by a high rate of proliferation, fibrovascular development, cellular migration, corneal…”
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