Search Results - "Tojo, S J"

Induction of Heme Oxygenase-1 Suppresses Venular Leukocyte Adhesion Elicited by Oxidative Stress: Role of Bilirubin Generated by the Enzyme by Hayashi, Shinobu, Takamiya, Rina, Yamaguchi, Tokio, Matsumoto, Kenji, Tojo, Shinichiro J, Tamatani, Takuya, Kitajima, Masaki, Makino, Nobuya, Ishimura, Yuzuru, Suematsu, Makoto

“…This study aimed to examine whether an elevated activity of heme oxygenase (HO)-1 in the tissue attenuates endothelial cell-leukocyte interactions microvessels…”
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Anti-P-selectin antibody attenuates rat brain ischemic injury by Suzuki, H, Hayashi, T, Tojo, S.J, Kitagawa, H, Kimura, K, Mizugaki, M, Itoyama, Y, Abe, K

“…We examined a protective effect of anti-P-selectin monoclonal antibody against rat ischemic brain injury with 24 h of middle cerebral artery occlusion (MCAO)…”
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Retinal ischemia-reperfusion injury attenuated by blocking of adhesion molecules of vascular endothelium by Tsujikawa, A, Ogura, Y, Hiroshiba, N, Miyamoto, K, Kiryu, J, Tojo, SJ, Miyasaka, M, Honda, Y

“…To evaluate quantitatively the effects of blocking of adhesion molecules (P-selectin or intercellular adhesion molecule-1 [ICAM-1]) on leukocyte dynamics in…”
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In Vivo Evaluation of Platelet-Endothelial Interactions after Transient Retinal Ischemia by Nishijima, Kazuaki, Kiryu, Junichi, Tsujikawa, Akitaka, Honjo, Megumi, Nonaka, Atsushi, Yamashiro, Kenji, Tanihara, Hidenobu, Tojo, Shinichiro J, Ogura, Yuichiro, Honda, Yoshihito

“…Accumulating evidence suggests that platelets play an important role in ischemia-reperfusion injury. To fulfill that role, platelets flowing in the bloodstream…”
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Contribution of E-selectin to cellular infiltration during endotoxin- induced uveitis by Suzuma, I, Mandai, M, Suzuma, K, Ishida, K, Tojo, SJ, Honda, Y

“…The selectin family is a group of early-reactive adhesion molecules that plays a role in the rolling phase of leukocytes in cellular infiltration. It has been…”
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Selectin on activated platelets enhances neutrophil endothelial adherence in myocardial reperfusion injury by KOGAKI, S, SAWA, Y, SANO, T, MATSUSHITA, T, OHATA, T, KUROTOBI, S, TOJO, S. J, MATSUDA, H, OKADA, S

“…The glycoprotein P-selectin is an adhesion molecule that is rapidly expressed on the surface of platelets and endothelium during the inflammatory process…”
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Inhibition of P-selectin attenuates neutrophil-mediated myocardial dysfunction in isolated rat heart by Ohnishi, Masako, Yamada, Kazuto, Morooka, Shigeaki, Tojo, Shinichiro J

“…The expression of P-selectin on postischemic endothelium after reperfusion has been shown to trigger neutrophil attachment and the subsequent inflammatory…”
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The role of P-selectin, sialyl Lewis X and sulfatide in myocardial ischemia and reperfusion injury by Yamada, Kazuto, Tojo, Shinichiro J, Hayashi, Masaji, Morooka, Shigeaki

“…The role of P-selectin and the ligands of selectins such as sialyl Lewis X and sulfatide was studied in a myocardial ischemia and reperfusion injury model…”
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Role of P-selectin in endotoxin-induced uveitis by Suzuma, K, Mandai, M, Kogishi, J, Tojo, SJ, Honda, Y, Yoshimura, N

“…P-selectin is one of the early-reactive adhesion molecules that play a part in the rolling phase of leukocytes in cellular infiltration. The study objective…”
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Protective effects of sialyl Lewis X and anti-P-selectin antibody against lipopolysaccharide-induced acute lung injury in rabbits by Hayashi, Hirotsugu, Koike, Haruhiko, Kurata, Yukiko, Imanishi, Noriaki, Tojo, Shinichiro J.

“…The prophylactic effects of selectin inhibitors on lipopolysaccharide-induced acute lung injury were studied in rabbits by using sialyl Lewis X-oligosaccharide…”
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In Vivo Evaluation of Platelet-Endothelial Interactions in Retinal Microcirculation of Rats by Tsujikawa, Akitaka, Kiryu, Junichi, Nonaka, Atsushi, Yamashiro, Kenji, Nishiwaki, Hirokazu, Tojo, Shinichiro J, Ogura, Yuichiro, Honda, Yoshihito

“…This study was designed to develop a new method to evaluate the dynamics of platelets in the retinal microcirculation in vivo and to investigate quantitatively…”
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Differing Patterns of P-Selectin Expression in Lung Injury by Bless, Nicolas M., Tojo, Shinichiro J., Kawarai, Hiroko, Natsume, Yasuhiro, Lentsch, Alex B., Padgaonkar, Vaishalee A., Czermak, Boris J., Schmal, Hagen, Friedl, Hans P., Ward, Peter A.

“…Using two models of acute lung inflammatory injury in rats (intrapulmonary deposition of immunoglobulin G immune complexes and systemic activation of…”
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The effects of delayed treatment with sialyl Lewis X against lipopolysaccharide-induced acute lung injury in rabbits by Hayashi, Hirotsugu, Koike, Haruhiko, Imanishi, Noriaki, Tojo, Shinichiro J

“…The therapeutic effects of a selectin inhibitor against lipopolysaccharide-induced acute lung injury were studied in rabbits by using sialyl Lewis…”
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In vivo neutralization of P-selectin inhibits leukocyte-endothelial interactions in retinal microcirculation during ocular inflammation by MIYAMOTO, K, OGURA, Y, HAMADA, M, NISHIWAKI, H, HIROSHIBA, N, TSUJIKAWA, A, MANDAI, M, SUZUMA, K, TOJO, S. J, HONDA, Y

“…P-selectin is one of the adhesion molecules involved in leukocyte rolling during an inflammatory reaction. The aim of this study was to examine the role of…”
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Role of P-selectin in the early stage of the Arthus reaction by Ohnishi, Masako, Koike, Haruhiko, Kawamura, Nobuko, Tojo, Shinichiro J., Hayashi, Masaji, Morooka, Shigeaki

“…P-selectin is rapidly translocated to the surface of endothelial cells and platelets following exposure to chemical mediators such as histamine, thrombin and…”
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Genes expressed during imaginal discs morphogenesis: IMP-L2, a gene expressed during imaginal disc and imaginal histoblast morphogenesis by Osterbur, David L., Fristrom, Dianne K., Natzle, Jeanette E., Tojo, Shinichiro J., Fristrom, James W.

“…We describe our analysis of IMP-L2, one of a set of six ecdysone-inducible genes in imaginal discs of Drosophila whose transcripts are associated with…”
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Polarized secretion of an ectopic protein in Drosophila salivary glands in vivo by Tojo, S. J., Germeraad, S., King, D. S., Fristrom, J. W.

“…Epithelial cells can secrete specific proteins in a polarized manner, either from the apical or basolateral surface. Intracellular protein sorting which…”
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P-selectin participates in cardiopulmonary bypass–induced inflammatory response in association with nitric oxide and peroxynitrite production by Hayashi, Yoshitaka, Sawa, Yoshiki, Nishimura, Motonobu, Tojo, Shinichiro J., Fukuyama, Naoto, Nakazawa, Hiroe, Matsuda, Hikaru

“…Objectives: P-selectin participates in the development of inflammatory disorders. Cardiopulmonary bypass is thought to induce inflammatory response and…”
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Adhesive interaction between P-selectin and sialyl Lewis(x) plays an important role in recurrent coronary arterial thrombosis in dogs by Ikeda, H, Ueyama, T, Murohara, T, Yasukawa, H, Haramaki, N, Eguchi, H, Katoh, A, Takajo, Y, Onitsuka, I, Ueno, T, Tojo, S J, Imaizumi, T

“…Cell adhesion molecules may play an important role in the disease process of acute coronary syndromes. We have shown a neutralizing anti-P-selectin monoclonal…”
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Reduction of ischemic brain injury by anti-P-selectin monoclonal antibody after permanent middle cerebral artery occlusion in rat by Suzuki, Hitoshi, Abe, Koji, Tojo, Shinichiro J., Kitagawa, Hisashi, Kimura, Katsuhiko, Mizugaki, Michinao, Itoyama, Yasuto

“…The selectin family of adhesion molecules is involved in adhesion of leukocyte to microcirculatory system and the transmigration into brain parenchyma…”
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