Search Results - "Toh, Hong"

Dysregulation of intracellular trafficking and endosomal sorting in Alzheimer's disease: controversies and unanswered questions by Toh, Wei Hong, Gleeson, Paul A

“…Alzheimer's disease (AD) is characterized by the accumulation of amyloid plaques in the brain consisting of an aggregated form of amyloid β-peptide (Aβ)…”
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Cystic nodal metastasis in patients with oropharyngeal squamous cell carcinoma receiving chemoradiotherapy: Relationship with human papillomavirus status and failure patterns by Huang, Yu-Han, Yeh, Chih-Hua, Cheng, Nai-Ming, Lin, Chien-Yu, Wang, Hung-Ming, Ko, Sheung-Fat, Toh, Cheng-Hong, Yen, Tzu-Chen, Liao, Chun-Ta, Ng, Shu-Hang

“…We investigated the relationships of cystic nodal metastasis, human papillomavirus (HPV) status, and treatment failure patterns in patients with oropharyngeal…”
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Safety and tolerability of asunercept plus standard radiotherapy/temozolomide in Asian patients with newly-diagnosed glioblastoma: a phase I study by Wei, Kuo-Chen, Hsu, Peng-Wei, Tsai, Hong-Chieh, Lin, Ya-Jui, Chen, Ko-Ting, Toh, Cheng-Hong, Huang, Hui-Lin, Jung, Shih-Ming, Tseng, Chen-Kan, Ke, Yu-Xiong

“…Asunercept (company code APG101 [Apogenix AG]; company code CAN008 [CANbridge Pharmaceuticals]) is a novel glycosylated fusion protein that has shown promising…”
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SEARCH 8Es: A novel point of care ultrasound protocol for patients with chest pain, dyspnea or symptomatic hypotension in the emergency department by Ahn, Jung Hwan, Jeon, Jin, Toh, Hong-Chuen, Noble, Vicki Elizabeth, Kim, Jun Su, Kim, Young Sik, Do, Han Ho, Ha, Young Rock

“…This study was conducted to evaluate a problem-oriented focused torso bedside ultrasound protocol termed "Sonographic Evaluation of Aetiology for Respiratory…”
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Glymphatic Dysfunction in Patients With Ischemic Stroke by Toh, Cheng Hong, Siow, Tiing Yee

“…Objectives: Rodent experiments have provided some insight into the changes of glymphatic function in ischemic stroke. The diffusion tensor image analysis along…”
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Factors Associated With Dysfunction of Glymphatic System in Patients With Glioma by Toh, Cheng Hong, Siow, Tiing Yee

“…Rodent experiments have provided some insights into the changes of glymphatic function associated with glioma growth. The diffusion tensor image analysis along…”
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A Neural Network Approach to Identify Glioblastoma Progression Phenotype from Multimodal MRI by Yan, Jiun-Lin, Toh, Cheng-Hong, Ko, Li, Wei, Kuo-Chen, Chen, Pin-Yuan

“…The phenotypes of glioblastoma (GBM) progression after treatment are heterogeneous in both imaging and clinical prognosis. This study aims to apply radiomics…”
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MRI Radiomics for Predicting Survival in Patients with Locally Advanced Hypopharyngeal Cancer Treated with Concurrent Chemoradiotherapy by Siow, Tiing Yee, Yeh, Chih-Hua, Lin, Gigin, Lin, Chien-Yu, Wang, Hung-Ming, Liao, Chun-Ta, Toh, Cheng-Hong, Chan, Sheng-Chieh, Lin, Ching-Po, Ng, Shu-Hang

“…A reliable prognostic stratification of patients with locally advanced hypopharyngeal cancer who had been treated with concurrent chemoradiotherapy (CCRT) is…”
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Clinically integrated multi-organ point-of-care ultrasound for undifferentiated respiratory difficulty, chest pain, or shock: a critical analytic review by Ha, Young-Rock, Toh, Hong-Chuen

“…Rapid and accurate diagnosis and treatment are paramount in the management of the critically ill. Critical care ultrasound has been widely used as an adjunct…”
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Peritumoral Brain Edema in Meningiomas May Be Related to Glymphatic Dysfunction by Toh, Cheng Hong, Siow, Tiing Yee, Castillo, Mauricio

“…The pathogenesis of peritumoral brain edema (PTBE) in meningiomas remains unclear. The glymphatic system is recently recognized as a pathway for waste…”
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Magnetic Resonance Images Implicate That Glymphatic Alterations Mediate Cognitive Dysfunction in Alzheimer Disease by Hsu, Jung‐Lung, Wei, Yi‐Chia, Toh, Cheng Hong, Hsiao, Ing‐Tsung, Lin, Kun‐Ju, Yen, Tzu‐Chen, Liao, Ming‐Feng, Ro, Long‐Sun

“…Objective The glymphatic system cleans amyloid and tau proteins from the brain in animal studies of Alzheimer disease (AD). However, there is no direct…”
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Prognostic impact of combining whole-body PET/CT and brain PET/MR in patients with lung adenocarcinoma and brain metastases by Ho, Kung-Chu, Toh, Cheng-Hong, Li, Shih-Hong, Liu, Chien-Ying, Yang, Cheng-Ta, Lu, Yu-Jen, Su, Tzu-Pei, Wang, Chih-Wei, Yen, Tzu-Chen

“…Purpose The role of brain FDG-PET in patients with lung cancer and brain metastases remains unclear. Here, we sought to determine the prognostic significance…”
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Role of NADPH Oxidase in Retinal Microvascular Permeability Increase by RAGE Activation by Warboys, Christina M, Toh, Hong-Boon, Fraser, Paul A

“…The accumulation of advanced glycation end products (AGEs) within the retina in diabetes is associated with a chronic increase in retinal microvascular…”
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Peritumoral Brain Edema in Metastases May Be Related to Glymphatic Dysfunction by Toh, Cheng Hong, Siow, Tiing Yee, Castillo, Mauricio

“…The proliferation of microvessels with increased permeability is thought to be the cause of peritumoral brain edema (PTBE) in metastases. The contribution of…”
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FcRn mediates fast recycling of endocytosed albumin and IgG from early macropinosomes in primary macrophages by Toh, Wei Hong, Louber, Jade, Mahmoud, Ismail S, Chia, Jenny, Bass, Greg T, Dower, Steve K, Verhagen, Anne M, Gleeson, Paul A

“…The neonatal Fc receptor (FcRn) rescues albumin and IgG following endocytosis and thereby extends the half-life of these plasma proteins. However, the pathways…”
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Hospital seeing more personal mobility device accidents and serious injuries despite active mobility act by Lee, Wey, Goo, Tiong, Lim, Woan, Toh, Hong, Yasai, Yu

“…Introduction: E-scooters or personal mobility devices (PMDs) have recently been growing in popularity in Singapore. These devices can be especially helpful for…”
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Reduced Sleep Quality Is Related to Poor Quality of Life in Patients with Juvenile Myoclonic Epilepsy, a Case-Control Study by Lin, Chih-Yin, Wu, Tony, Chang, Chun-Wei, Hsieh, Hsiang-Yao, Cheng, Mei-Yun, Tseng, Wei-En Johnny, Lin, Wey-Ran, Toh, Cheng-Hong, Chao, Yi-Ping, Liu, Chun-Jing, Lim, Siew-Na

“…Juvenile myoclonic epilepsy (JME) is a primary generalized epilepsy which is closely related to the sleep-wake cycle. This study aimed to investigate whether…”
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Brain Abscess Apparent Diffusion Coefficient is Associated With Microbial Culture Yields by Toh, Cheng Hong, Siow, Tiing Yee, Wong, Alex Mun‐Ching, Castillo, Mauricio

“…Background Obtaining pus for microbial cultures is one of the surgical aims in patients with brain abscess. Predictors of microbial yields are necessary as…”
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A rare case of acral persistent papular mucinosis by Toh, Joseph Jia‐Hong, Goh, Nicholas Seng-Geok, Wang, Ding Yuan

“…In patients with asymptomatic papules of hands and feet, a clinical differential of acral persistent papular mucinosis should be thought of. In patients with…”
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Spectrum of neuroimaging mimics in children with COVID-19 infection by Wong, Alex Mun-Ching, Toh, Cheng Hong

“…Coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2, has affected over 200 million people globally (including over 30 million people in the United…”
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