Search Results - "Toh, D"

Congenital absence of inferior vena cava: an under recognised cause of unprovoked venous thromboembolism by Chew, R R, Lim, A H, Toh, D

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Chemical etching of silicon carbide in pure water by using platinum catalyst by Isohashi, Ai, Bui, P. V., Toh, D., Matsuyama, S., Sano, Y., Inagaki, K., Morikawa, Y., Yamauchi, K.

“…Chemical etching of SiC was found to proceed in pure water with the assistance of a Pt catalyst. A 4H-SiC (0001) wafer was placed and slid on a polishing pad…”
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Bias-assisted photoelectrochemical planarization of GaN (0001) with impurity concentration distribution by Toh, D., Kayao, K., Ohnishi, R., Osaka, A. I., Yamauchi, K., Sano, Y.

“…To planarize semiconductor materials such as gallium nitride (GaN) and silicon carbide with high efficiency, we developed a polarization method that combines…”
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Polarisome scaffolder Spa2-mediated macromolecular condensation of Aip5 for actin polymerization by Xie, Ying, Sun, Jialin, Han, Xiao, Turšić-Wunder, Alma, Toh, Joel D. W., Hong, Wanjin, Gao, Yong-Gui, Miao, Yansong

“…A multiprotein complex polarisome nucleates actin cables for polarized cell growth in budding yeast and filamentous fungi. However, the dynamic regulations of…”
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Outlier or handover: outcomes for General Medicine inpatients by Thompkins, S., Schaefer, S., Toh, D., Horwood, C., Thompson, C. H.

“…Objective Patients admitted from the emergency department may be co-located on the treating team’s ‘home ward’. If no bed is available, patients may be sent to…”
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Building pharmacogenetics into a pharmacovigilance program in Singapore: using serious skin rash as a pilot study by Toh, D S L, Tan, L L, Aw, D C W, Pang, S M, Lim, S H, Thirumoorthy, T, Lee, H Y, Tay, Y K, Tan, S K, Vasudevan, A, Lateef, A, Chong, Y Y, Chan, Y C, Loke, C, Chan, C L, Koay, E S C, Ren, E C, Lee, E J D, Sung, C

“…To study the possible genetic associations with adverse drug reactions (ADR), the Singapore Health Sciences Authority (HSA) has piloted a program to collect…”
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State-of-Charge Estimation and Active Cell Pack Balancing Design of Lithium Battery Power System for Smart Electric Vehicle by Chiew, J., Toh, W. D., Chin, C. S., Gao, Z. C., Jia, J.

“…This paper presents an integrated state-of-charge (SOC) estimation model and active cell balancing of a 12-cell lithium iron phosphate (LiFePO4) battery power…”
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Drug-induced liver injury associated with Complementary and Alternative Medicine: a review of adverse event reports in an Asian community from 2009 to 2014 by Teo, Desmond Chun Hwee, Ng, Patricia Suet Leng, Tan, Siew Har, Lim, Adena Theen, Toh, Dorothy Su Lin, Chan, Sui Yung, Cheong, Han Hui

“…The use of Complementary and Alternative Medicine (CAM) has been increasing over the years. A recent review of adverse event reports (AERs) associated with CAM…”
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Markers of Focal and Diffuse Nonischemic Myocardial Fibrosis Are Associated With Adverse Cardiac Remodeling and Prognosis in Patients With Hypertension: The REMODEL Study by Iyer, Nithin R., Le, Thu-Thao, Kui, Michelle S.L., Tang, Hak-Chiaw, Chin, Chee-Tang, Phua, Soon-Kieng, Bryant, Jennifer A., Pua, Chee-Jian, Ang, Briana, Toh, Desiree-Faye, Aw, Tar-Choon, Lee, Chi-Hang, Cook, Stuart A., Ugander, Martin, Chin, Calvin W.L.

“…The prognostic significance of focal and diffuse myocardial fibrosis in patients with cardiovascular risk factors is unclear. REMODEL (Response of the…”
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Systems analysis of a quorum sensing network: Design constraints imposed by the functional requirements, network topology and kinetic constants by Goryachev, A.B., Toh, D.J., Lee, T.

“…Understanding the relationship between the structural organization of intracellular decision networks and the observable phenotypes they control is one of the…”
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Pharmacogenomic diversity in Singaporean populations and Europeans by Brunham, L R, Chan, S L, Li, R, Aminkeng, F, Liu, X, Saw, W Y, Ong, R T H, Pillai, E N, Carleton, B C, Toh, D, Tan, S H, Koo, S H, Lee, E J D, Chia, K S, Ross, C J D, Hayden, M R, Sung, C, Teo, Y Y

“…Differences in the frequency of pharmacogenomic variants may influence inter-population variability in drug efficacy and risk of adverse drug reactions (ADRs)…”
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Distinct RNA N-demethylation pathways catalyzed by nonheme iron ALKBH5 and FTO enzymes enable regulation of formaldehyde release rates by Toh, Joel D. W., Crossley, Steven W. M., Bruemmer, Kevin J., Ge, Eva J., He, Dan, Iovan, Diana A., Chang, Christopher J.

“…The AlkB family of nonheme Fe(II)/2-oxoglutarate–dependent oxygenases are essential regulators of RNA epigenetics by serving as erasers of one-carbon marks on…”
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N6-Methyladenosine: a conformational marker that regulates the substrate specificity of human demethylases FTO and ALKBH5 by Zou, Shui, Toh, Joel D. W., Wong, Kendra H. Q., Gao, Yong-Gui, Hong, Wanjin, Woon, Esther C. Y.

“…N 6 -Methyladenosine (m6A) is currently one of the most intensively studied post-transcriptional modifications in RNA. Due to its critical role in epigenetics…”
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Single-nucleotide-resolution sequencing of human N 6-methyldeoxyadenosine reveals strand-asymmetric clusters associated with SSBP1 on the mitochondrial genome by Koh, Casslynn W Q, Goh, Yeek Teck, Toh, Joel D W, Neo, Suat Peng, Ng, Sarah B, Gunaratne, Jayantha, Gao, Yong-Gui, Quake, Stephen R, Burkholder, William F, Goh, Wee Siong S

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Low-temperature macro-encapsulated phase change material based thermal energy storage system without air void space design by Chiew, J., Chin, C.S., Toh, W.D., Gao, Z., Jia, J.

“…•Eliminate air void and give good heat transfer between PCM and housing by dampeners.•Results show air void in macro-encapsulation affects heat transfer…”
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Formaldehyde regulates S -adenosylmethionine biosynthesis and one-carbon metabolism by Pham, Vanha N, Bruemmer, Kevin J, Toh, Joel D W, Ge, Eva J, Tenney, Logan, Ward, Carl C, Dingler, Felix A, Millington, Christopher L, Garcia-Prieto, Carlos A, Pulos-Holmes, Mia C, Ingolia, Nicholas T, Pontel, Lucas B, Esteller, Manel, Patel, Ketan J, Nomura, Daniel K, Chang, Christopher J

“…One-carbon metabolism is an essential branch of cellular metabolism that intersects with epigenetic regulation. In this work, we show how formaldehyde (FA), a…”
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A strategy based on nucleotide specificity leads to a subfamily-selective and cell-active inhibitor of N 6 -methyladenosine demethylase FTO by Toh, Joel D W, Sun, Lingyi, Lau, Lisa Z M, Tan, Jackie, Low, Joanne J A, Tang, Colin W Q, Cheong, Eleanor J Y, Tan, Melissa J H, Chen, Yun, Hong, Wanjin, Gao, Yong-Gui, Woon, Esther C Y

“…The AlkB family of nucleic acid demethylases are of intense biological and medical interest because of their roles in nucleic acid repair and epigenetic…”
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Single-nucleotide-resolution sequencing of human N6-methyldeoxyadenosine reveals strand-asymmetric clusters associated with SSBP1 on the mitochondrial genome by Koh, Casslynn W Q, Goh, Yeek Teck, Toh, Joel D W, Neo, Suat Peng, Ng, Sarah B, Gunaratne, Jayantha, Gao, Yong-Gui, Quake, Stephen R, Burkholder, William F, Goh, Wee Siong S

“…Abstract N 6-methyldeoxyadenosine (6mA) is a well-characterized DNA modification in prokaryotes but reports on its presence and function in mammals have been…”
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Purification-Free, Small-Scale Synthesis of Isothiocyanates by Reagentless Fragmentation of Polymer-Supported 1,4,2-Oxathiazoles by Burkett, Brendan A., Fu, Pincheng, Hewitt, Russell J., Ng, Su Ling, Toh, Joel D. W.

“…The synthesis of isothiocyanates (ITCs) by employing polymer‐supported 1,4,2‐oxathiazoles is described. The ITCs are obtained in moderate yields and high…”
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Cardiac magnetic resonance (CMR) height-based allometric scaling in Southeast Asians; implications in the diagnosis and prognosis of left ventricular hypertrophy (LVH): the REMODEL study by Lee, C C E, Chan, R, Toh, D F, Kui, M, Lee, V, Bryant, J A, Boubertakh, R, Lee, C H, Chai, P, Le, T T, Chin, C W L

“…Abstract Background Left ventricular hypertrophy (LVH) is a strong predictor of adverse cardiovascular outcomes (1). Although normalizing LV mass (LVM) to…”
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