Search Results - "Toh, B. H"

Nonmyeloablative Conditioning Generates Autoantigen‐Encoding Bone Marrow That Prevents and Cures an Experimental Autoimmune Disease by Nasa, Z., Chung, J.‐Y., Chan, J., Toh, B.‐H., Alderuccio, F.

“…Autoimmune diseases result from chronic targeted immune responses that lead to tissue pathology and disease. The potential of autologous hematopoietic stem…”
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EEA1 links PI(3)K function to Rab5 regulation of endosome fusion by Stenmark, Harald, Simonsen, Anne, Lippe, Roger, Christoforidis, Savvas, Gaullier, Jean-Michel, Brech, Andreas, Callaghan, Judy, Toh, Ban-Hock, Murphy, Carol, Zerial, Marino

“…GTPases and lipid kinases regulate membrane traffic along the endocytic pathway by mechanisms that are not completely understood. Fusion between early…”
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Cell division autoantigen 1 plays a profibrotic role by modulating downstream signalling of TGF-β in a murine diabetic model of atherosclerosis by Pham, Y, Tu, Y, Wu, T, Allen, T. J, Calkin, A. C, Watson, A. M, Li, J, Jandeleit-Dahm, K. A, Toh, B-H, Cao, Z, Cooper, M. E, Chai, Z

“…Aims/hypothesis Excess accumulation of vascular extracellular matrix (ECM) is an important pathological process in cardiovascular diseases including…”
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Non-myeloablative transplantation of bone marrow expressing self-antigen establishes peripheral tolerance and completely prevents autoimmunity in mice by Hosseini, H, Oh, D Y, Chan, S T, Chen, X T, Nasa, Z, Yagita, H, Alderuccio, F, Toh, B-H, Chan, J

“…Myeloablative transplantation of bone marrow (BM) engineered to express myelin oligodendrocyte glycoprotein (MOG) establishes central intrathymic tolerance and…”
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EEA1, an early endosome-associated protein. EEA1 is a conserved alpha-helical peripheral membrane protein flanked by cysteine "fingers" and contains a calmodulin-binding IQ motif by Mu, F T, Callaghan, J M, Steele-Mortimer, O, Stenmark, H, Parton, R G, Campbell, P L, McCluskey, J, Yeo, J P, Tock, E P, Toh, B H

“…Early endosomes are cellular compartments receiving endocytosed material and sorting them for vesicular transport to late endosomes and lysosomes or for…”
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Prednisolone promotes remission and gastric mucosal regeneration in experimental autoimmune gastritis by Biondo, M, Field, J, Toh, B-H, Alderuccio, F

“…A cardinal feature of organ‐specific autoimmunity is destructive pathology in the target organ. In human and experimental models of autoimmune gastritis,…”
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Study of factors affecting the hardness of ball bonds in copper wire bonding by Zhong, Z.W., Ho, H.M., Tan, Y.C., Tan, W.C., Goh, H.M., Toh, B.H., Tan, J.

“…Copper wire bonding has gained popularity due to its economic advantage and superior electrical performance. However, copper is harder than gold, and replacing…”
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Gastric H +, K +-adenosine triphosphatase β subunit is required for normal function, development, and membrane structure of mouse parietal cells by Scarff, Katrina L., Judd, Louise M., Toh, Ban–Hock, Gleeson, Paul A., van Driel, Ian R.

“…Background & Aims: Parietal cells of the gastric mucosa contain a complex and extensive secretory membrane system that harbors gastric H +,K +-adenosine…”
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Phosphatidylserine liposomes mimic apoptotic cells to attenuate atherosclerosis by expanding polyreactive IgM producing B1a lymphocytes by Hosseini, Hamid, Li, Yi, Kanellakis, Peter, Tay, Christopher, Cao, Anh, Tipping, Peter, Bobik, Alex, Toh, Ban-Hock, Kyaw, Tin

“…To investigate whether activation of atheroprotective peritoneal B1a cells by apoptotic cells or phosphatidylserine liposomes (PSLs) can enhance their…”
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Brain hypometabolic changes in 14 adolescent–adult patients with Niemann–Pick disease type C assessed by 18F-fluorodeoxyglucose positron emission tomography by Lau, Theodore Y., Kao, Yung Hsiang, Toh, H. B., Sivaratnam, Dinesh, Lichtenstein, Meir, Velakoulis, Dennis, Walterfang, Mark

“…Objective Niemann Pick disease type C (NPC) is a rare progressive neurovisceral lysosomal disorder caused by autosomal recessive mutations in the NPC1 or NPC2…”
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EEA1, a tethering protein of the early sorting endosome, shows a polarized distribution in hippocampal neurons, epithelial cells, and fibroblasts by Wilson, J M, de Hoop, M, Zorzi, N, Toh, B H, Dotti, C G, Parton, R G

“…EEA1 is an early endosomal Rab5 effector protein that has been implicated in the docking of incoming endocytic vesicles before fusion with early endosomes…”
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Cardiac FDG/PET imaging mimicking sarcoidosis by Lai, Jeffrey K.C., Teo, Eliza, Lichtenstein, Meir, Toh, H.B., Sivaratnam, Dinesh

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Analysis of mononuclear cell infiltrate and cytokine production in murine autoimmune gastritis by Martinelli, TM, van Driel, IR, Alderuccio, F, Gleeson, PA, Toh, BH

“…BACKGROUND & AIMS: Murine autoimmune gastritis, induced by day-3 thymectomy, is characterized by cellular infiltrates and circulating autoantibodies to gastric…”
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Experimental Autoimmune Gastritis: Mouse Models Of Human Organ-specific Autoimmune Disease by Field, J., Biondo, M. A., Murphy, K., Alderuccio, F., Toh, B. H.

“…Experimental autoimmune gastritis (EAG) is an excellent model of human autoimmune gastritis, the underlying cause of pernicious anaemia. Murine autoimmune…”
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Organ-specific autoimmunity induced by lymphopenia by Gleeson, P A, Toh, B H, van Driel, I R

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Local Transgenic Expression of Granulocyte Macrophage-Colony Stimulating Factor Initiates Autoimmunity by Biondo, Mark, Nasa, Zeyad, Marshall, Aiden, Hock Toh, Ban, Alderuccio, Frank

“…Mechanisms leading to breakdown of immunological tolerance and initiation of autoimmunity are poorly understood. Experimental autoimmune gastritis is a…”
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Pernicious Anaemia by Toh, Ban-Hock, Alderuccio, Frank

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Quantitative assessment of thyroid-to-background ratio improves the interobserver reliability of technetium-99m sestamibi thyroid scintigraphy for investigation of amiodarone-induced thyrotoxicosis by Pattison, David A, Westcott, James, Lichtenstein, Meir, Toh, H.B, Gunawardana, Dishan, Better, Nathan, Forehan, Simon, Sivaratnam, Dinesh

“…BACKGROUNDAmiodarone-induced thyrotoxicosis (AIT) is caused by excessive hormone synthesis and release (AIT I), a destructive thyroiditis (AIT II), or a…”
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Investigation of copper layers deposited by CVD using Cu(I)hfac(TMVS) precursor by TOH, B. H. W, MCNEILL, D. W, GAMBLE, H. S

“…Chemical vapour deposition (CVD) of copper on titanium-coated substrates was performed in a stainless steel reactor using copper(I) hexafluoroacetylacetonate…”
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M1 macrophages, key contributors to lymphoid neogenesis in atherosclerotic aorta by Bobik, Alexander, Kyaw, Tin Soe, Tipping, Peter, Toh, Ban-Hock

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