Search Results - "Toguchida, J."

Activation of the non-canonical Dvl-Rac1-JNK pathway by Frizzled homologue 10 in human synovial sarcoma by Fukukawa, C, Nagayama, S, Tsunoda, T, Toguchida, J, Nakamura, Y, Katagiri, T

“…We previously reported that Frizzled homologue 10 (FZD10), a member of the Wnt signal receptor family, was highly and specifically upregulated in synovial…”
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IKKβ in postnatal perichondrium remotely controls endochondral ossification of the growth plate through downregulation of MCP-5 by Kobayashi, K, Toguchida, J, Karin, M, Kato, T

“…I κ B kinase β (IKK β ) is a catalytic subunit of the IKK complex, which activates nuclear factor- κ B (NF- κ B). Although its role in osteoclastogenesis is…”
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PGE2 signal via EP2 receptors evoked by a selective agonist enhances regeneration of injured articular cartilage by Otsuka, S., M.D, Aoyama, T., M.D., Ph.D, Furu, M., M.D, Ito, K., M.D, Jin, Y., M.D, Nasu, A., M.D, Fukiage, K., M.D, Kohno, Y., M.D., Ph.D, Maruyama, T., Ph.D, Kanaji, T, Nishiura, A., Ph.D, Sugihara, H, Fujimura, S, Otsuka, T., M.D., Ph.D, Nakamura, T., M.D., Ph.D, Toguchida, J., M.D., Ph.D

“…Summary Objective The effect of the prostaglandin E2 (PGE2) signal through prostaglandin E receptor 2 (EP2) receptors on the repair of injured articular…”
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Identification of AFAP1L1 as a prognostic marker for spindle cell sarcomas by Furu, M, Kajita, Y, Nagayama, S, Ishibe, T, Shima, Y, Nishijo, K, Uejima, D, Takahashi, R, Aoyama, T, Nakayama, T, Nakamura, T, Nakashima, Y, Ikegawa, M, Imoto, S, Katagiri, T, Nakamura, Y, Toguchida, J

“…Spindle cell sarcomas consist of tumors with different biological features, of which distant metastasis is the most ominous sign for a poor prognosis. However,…”
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Role of uppermost superficial surface layer of articular cartilage in the lubrication mechanism of joints by KUMAR, P., OKA, M., TOGUCHIDA, J., KOBAYASHI, M., UCHIDA, E., NAKAMURA, T., TANAKA, K.

“…The uppermost superficial surface layer of articular cartilage, the ‘lamina splendens’ which provides a very low friction lubrication surface in articular…”
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Understanding the pathophysiology of NOMID arthropathy for drug discovery by iPSCs technology by Nakagawa, K, Okuno, Y, Nishikomori, R, Yokoyama, K, Tanaka, T, Kawai, T, Yasumi, T, Umeda, K, Nakayama, N, Toguchida, J, Hagiwara, M, Heike, T

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Expression of the cadherin-11 gene is a discriminative factor between articular and growth plate chondrocytes by Matsusaki, T., Aoyama, T., Nishijo, K., Okamoto, T., Nakayama, T., Nakamura, T., Toguchida, J.

“…Calcification of hypertrophic chondrocytes is the final step in the differentiation of growth plates, although the precise mechanism is not known. We have…”
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MP-15.09: Functional Analysis of a Novel Soft Tissue Sarcoma Metastasis-Associated Molecule in Prostate Cancer by Kajita, Y, Furu, M, Nagayama, S, Nishiyama, H, Nakamura, E, Ogawa, O, Toguchida, J

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Mediastinal synovial sarcoma by Katakura, H, Fukuse, T, Shiraishi, I, Hayatsu, E, Nishijo, K, Toguchida, J, Nakashima, Y, Wada, H

“…Synovial sarcoma of the mediastinum is a rare neoplasm that has overlapping histological and immunophenotypic features with other tumors in the differential…”
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High incidence of SV40-like sequences detection in tumour and peripheral blood cells of Japanese osteosarcoma patients by YAMAMOTO, H, NAKAYAMA, T, MURAKAMI, H, HOSAKA, T, NAKAMATA, T, TSUBOYAMA, T, OKA, M, NAKAMURA, T, TOGUCHIDA, J

“…Recent studies have revealed the evidence for the significance of SV40 genome in human malignancies. In this paper, the presence of SV40-like sequences was…”
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p53 expression and its relationship to DNA alterations in bone and soft tissue sarcomas by WADAYAMA, B, TOGUCHIDA, J, YAMAGUCHI, T, SASAKI, M. S, KOTOURA, Y, YAMAMURO, T

“…The p53 gene is one of the best studied tumour suppressor genes. Recently we performed mutation analysis on the p53 gene in a large number of bone and soft…”
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Anisotropy of osteoporotic cancellous bone by Sugita, H, Oka, M, Toguchida, J, Nakamura, T, Ueo, T, Hayami, T

“…To investigate the mechanism underlying femoral neck fracture, it is necessary to determine the various mechanical properties, including the bone strength, of…”
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Complete genomic sequence of the human retinoblastoma susceptibility gene by Toguchida, J, McGee, T L, Paterson, J C, Eagle, J R, Tucker, S, Yandell, D W, Dryja, T P

“…A 180,388-bp contig encompassing the human retinoblastoma gene was sequenced in its entirety. Partial analysis of the sequence revealed (1) a high (A+T)/(G+C)…”
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Intra-operative radiation therapy for osteosarcoma in the extremities by TSUBOYAMA, T, TOGUCHIDA, J, KOTOURA, Y, KASAHARA, K, HIRAOKA, M, NAKAMURA, T

“…The outcome following intra-operative radiation therapy in the treatment of osteosarcoma in the extremity in 33 patients was evaluated for oncological and…”
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1482O A phase III study comparing methotrexate (M), adriamycin (A) and cisplatin (P) with MAP + ifosfamide (MAP + IF) for the treatment of osteosarcoma: JCOG0905 by Hiraga, H., Machida, R., Kawai, A., Matsumoto, Y., Yonemoto, T., Nishida, Y., Nagano, A., Ae, K., Yoshida, S., Asanuma, K., Toguchida, J., Huruta, D., Nakayama, R., Akisue, T., Hiruma, T., Morii, T., Tanaka, K., Kataoka, T., Fukuda, H., Ozaki, T.

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Detection of mutations of the RB1 gene in retinoblastoma patients by using exon-by-exon PCR-SSCP analysis by Shimizu, T, Toguchida, J, Kato, M V, Kaneko, A, Ishizaki, K, Sasaki, M S

“…Most sporadic cases of retinoblastoma, malignant eye tumor of children, may require the identification of a mutation of the retinoblastoma gene (RB1 gene) for…”
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IKK[beta] in postnatal perichondrium remotely controls endochondral ossification of the growth plate through downregulation of MCP-5 by Kobayashi, K, Toguchida, J, Karin, M, Kato, T

“…IκB kinase β (IKKβ) is a catalytic subunit of the IKK complex, which activates nuclear factor-κB (NF-κB). Although its role in osteoclastogenesis is well…”
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Preliminary study of polyvinyl alcohol-hydrogel (PVA-H) artificial meniscus by Kobayashi, Masanori, Toguchida, Jyunya, Oka, Masanori

“…Nowadays the importance of knee meniscal function is recognized. The treatment for meniscus injury has been changing from resection to repair. However,…”
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Establishment of an osteoblast-like cell line, MMC2, from p53-deficient mice by Nakayama, T., Kanoe, H., Sasaki, M.S., Aizawa, S., Nakamura, T., Toguchida, J.

“…An immortalized cell line exhibiting a well-differentiated osteoblast-like phenotype was established from calvaria of p53 tumor suppressor-deficient mice. This…”
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Multiple exostoses by Toguchida, J, Nagayama, S

“…Multiple exostoses is a hereditary disease characterized by multiple osteocartilagenous tumors, of which the histological structures are similar to those of…”
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