Search Results - "Toguchi, Mariko"

Development of an anti-hepatitis B virus (HBV) agent through the structure-activity relationship of the interferon-like small compound CDM-3008 by Takahashi, Nobuaki, Hayashi, Kyohei, Nakagawa, Yusuke, Furutani, Yutaka, Toguchi, Mariko, Shiozaki-Sato, Yumi, Sudoh, Masayuki, Kojima, Soichi, Kakeya, Hideaki

“…[Display omitted] Hepatitis B, a viral infectious disease caused by hepatitis B virus (HBV), is a life-threatening disease that leads liver cirrhosis and liver…”
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Establishment of a Rapid Detection System for ISG20-Dependent SARS-CoV-2 Subreplicon RNA Degradation Induced by Interferon-α by Furutani, Yutaka, Toguchi, Mariko, Higuchi, Shoko, Yanaka, Kaori, Gailhouste, Luc, Qin, Xian-Yang, Masaki, Takahiro, Ochi, Sae, Matsuura, Tomokazu

“…Inhaled nebulized interferon (IFN)-α and IFN-β have been shown to be effective in the management of coronavirus disease 2019 (COVID-19). We aimed to construct…”
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Phenosafranin inhibits nuclear localization of transglutaminase 2 without affecting its transamidase activity by Furutani, Yutaka, Toguchi, Mariko, Shrestha, Rajan, Kojima, Soichi

“…Transglutaminase 2 (TG2) localizes to the nucleus and induces apoptosis through a crosslinking inactivation of Sp1 in JHH-7 cells treated with acyclic…”
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An interferon-like small chemical compound CDM-3008 suppresses hepatitis B virus through induction of interferon-stimulated genes by Furutani, Yutaka, Toguchi, Mariko, Shiozaki-Sato, Yumi, Qin, Xian-Yang, Ebisui, Etsuko, Higuchi, Shoko, Sudoh, Masayuki, Suzuki, Harukazu, Takahashi, Nobuaki, Watashi, Koichi, Wakita, Takaji, Kakeya, Hideaki, Kojima, Soichi

“…Oral administration of nucleotide analogues and injection of interferon-α (IFNα) are used to achieve immediate suppression in replication of hepatitis B virus…”
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A small molecule iCDM-34 identified by in silico screening suppresses HBV DNA through activation of aryl hydrocarbon receptor by Furutani, Yutaka, Hirano, Yoshinori, Toguchi, Mariko, Higuchi, Shoko, Qin, Xian-Yang, Yanaka, Kaori, Sato-Shiozaki, Yumi, Takahashi, Nobuaki, Sakai, Marina, Kongpracha, Pornparn, Suzuki, Takehiro, Dohmae, Naoshi, Kukimoto-Niino, Mutsuko, Shirouzu, Mikako, Nagamori, Shushi, Suzuki, Harukazu, Kobayashi, Kaoru, Masaki, Takahiro, Koyama, Hiroo, Sekiba, Kazuma, Otsuka, Motoyuki, Koike, Kazuhiko, Kohara, Michinori, Kojima, Soichi, Kakeya, Hideaki, Matsuura, Tomokazu

“…IFN-alpha have been reported to suppress hepatitis B virus (HBV) cccDNA via APOBEC3 cytidine deaminase activity through interferon signaling. To develop a…”
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