Search Results - "Tognoni, M."

Microglial response to experimental periodontitis in a murine model of Alzheimer’s disease by Kantarci, Alpdogan, Tognoni, Christina M., Yaghmoor, Wael, Marghalani, Amin, Stephens, Danielle, Ahn, Jae-Yong, Carreras, Isabel, Dedeoglu, Alpaslan

“…Periodontal disease (PD) has been suggested to be a risk factor for Alzheimer’s disease (AD). We tested the impact of ligature-induced PD on 5xFAD mice and WT…”
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Microglial cell response to experimental periodontal disease by Almarhoumi, Rawan, Alvarez, Carla, Harris, Theodore, Tognoni, Christina M, Paster, Bruce J, Carreras, Isabel, Dedeoglu, Alpaslan, Kantarci, Alpdogan

“…Microglial activation is critical for modulating the neuroinflammatory process and the pathological progression of neurodegenerative diseases, such as…”
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Amyloid-β neuropathology induces bone loss in male mice by suppressing bone formation and enhancing bone resorption by Jung, Younghun, Ay, Birol, Cyr, Sajin M., Tognoni, Christina M., Klovdahl, Kaitlin, Matthias, Julia, Cui, Qiuxia, Brooks, Daniel J., Bouxsein, Mary L., Carreras, Isabel, Dedeoglu, Alpaslan, Bastepe, Murat

“…Alzheimer's disease (AD) and osteoporosis often coexist in the elderly. Although observational studies suggest an association between these two diseases, the…”
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Dysregulation of sphingosine-1-phosphate (S1P) and S1P receptor 1 signaling in the 5xFAD mouse model of Alzheimer’s disease by Jung, Younghun, Lopez-Benitez, Jonathan, Tognoni, Christina M., Carreras, Isabel, Dedeoglu, Alpaslan

“…[Display omitted] •Sphingolipid-1-phosphate (S1P) signaling through the activation S1P receptors (S1PRs) plays critical roles in cellular events in the…”
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Fingolimod mitigates memory loss in a mouse model of Gulf War Illness amid decreasing the activation of microglia, protein kinase R, and NFκB by Carreras, Isabel, Jung, Younghun, Lopez-Benitez, Jonathan, Tognoni, Christina M., Dedeoglu, Alpaslan

“…Gulf War Illness (GWI) is an unrelenting multi-symptom illness with chronic central nervous system and peripheral pathology affecting veterans from the 1991…”
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Dual dose-dependent effects of fingolimod in a mouse model of Alzheimer’s disease by Carreras, Isabel, Aytan, Nurgul, Choi, Ji-Kyung, Tognoni, Christina M., Kowall, Neil W., Jenkins, Bruce G., Dedeoglu, Alpaslan

“…Lipid metabolism is abnormal in Alzheimer’s disease (AD) brain leading to ceramide and sphingosine accumulation and reduced levels of brain…”
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Gα11 deficiency increases fibroblast growth factor 23 levels in a mouse model of familial hypocalciuric hypercalcemia by Ay, Birol, Cyr, Sajin Marcus, Klovdahl, Kaitlin, Zhou, Wen, Tognoni, Christina M, Iwasaki, Yorihiro, Rhee, Eugene P, Dedeoglu, Alpaslan, Simic, Petra, Bastepe, Murat

“…Fibroblast growth factor 23 (FGF23) production has recently been shown to increase downstream of Gαq/11-PKC signaling in osteocytes. Inactivating mutations in…”
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Nuclear receptor coactivators are coexpressed with steroid receptors and regulated by estradiol in mouse brain by Tognoni, Christina M, Chadwick, Jr, Joseph G, Ackeifi, Courtney A, Tetel, Marc J

“…The steroid hormones, including estradiol (E) and progesterone, act in the brain to regulate female reproductive behavior and physiology. These hormones…”
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Prenatal choline deficiency does not enhance hippocampal vulnerability after kainic acid-induced seizures in adulthood by Wong-Goodrich, Sarah J.E, Tognoni, Christina M, Mellott, Tiffany J, Glenn, Melissa J, Blusztajn, Jan K, Williams, Christina L

“…Abstract Choline is a vital nutrient needed during early development for both humans and rodents. Severe dietary choline deficiency during pregnancy leads to…”
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A RETROSPECTIVE MERGER ANALYSIS IN THE U.K. VIDEOGAME MARKET by Aguzzoni, L., Argentesi, E., Buccirossi, P., Ciari, L., Duso, T., Tognoni, M., Vitale, C.

“…We study the effect of a merger in a dynamic high-technology industry -- the videogame market -- which is characterized by the frequent introduction of new…”
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Sphingosine 1‐phosphate receptor signaling is dysregulated in a mouse model of Alzheimer's disease by Jung, Younghun, Lopez‐Benitez, Jonathan G, Tognoni, Christina M, Carreras, Isabel, Dedeoglu, Alpaslan

“…Background Sphingosine 1‐phosphate (S1P) through the activation of five G‐protein‐coupled S1P receptors 1‐5 (S1PR1‐5) plays crucial roles in cellular events…”
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Prognostic Value of Changes in N-Terminal Pro-Brain Natriuretic Peptide in Val-HeFT (Valsartan Heart Failure Trial) by Masson, Serge, PhD, Latini, Roberto, MD, Anand, Inder S., MD, FACC, FRCP, DPhil (Oxon), Barlera, Simona, MS, Angelici, Laura, MS, Vago, Tarcisio, BiolD, Tognoni, Gianni, MD, Cohn, Jay N., MD, FACC

“…Prognostic Value of Changes in N-Terminal Pro-Brain Natriuretic Peptide in Val-HeFT (Valsartan Heart Failure Trial) Serge Masson, Roberto Latini, Inder S…”
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Clinical Comparison With Short-Term Follow-Up of Bioresorbable Vascular Scaffold Versus Everolimus-Eluting Stent in Primary Percutaneous Coronary Interventions by Cortese, Bernardo, MD, Ielasi, Alfonso, MD, Romagnoli, Enrico, MD, Varricchio, Attilio, MD, PhD, Cuculo, Andrea, MD, Loi, Bruno, MD, Pisano, Francesco, MD, Corrado, Donatella, MD, Sesana, Marco, MD, La Vecchia, Luigi, MD, Summaria, Francesco, MD, Tespili, Maurizio, MD, Silva Orrego, Pedro, MD, Tognoni, Gianni, MD, Steffenino, Giuseppe, MD

“…Objective of this study was to assess the clinical performance of bioresorbable vascular scaffold (BVS) compared to everolimus-eluting stent (EES) in subjects…”
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Antiplatelet Therapy to Prevent Hemodialysis Vascular Access Failure: Systematic Review and Meta-analysis by Palmer, Suetonia C., MBChB, PhD, Di Micco, Lucia, MD, Razavian, Mona, MBBS, Craig, Jonathan C., MBChB, DCH, MM, PhD, Ravani, Pietro, MD, PhD, Perkovic, Vlado, MBBS, PhD, Tognoni, Gianni, MD, Graziano, Giusi, MSc, Jardine, Meg, MBBS, PhD, Pellegrini, Fabio, MSc, Nicolucci, Antonio, MD, Webster, Angela, MBBS, PhD, Strippoli, Giovanni F.M., MD, PhD, MPH, MM

“…Background Hemodialysis vascular access failure occurs often and increases morbidity for people on hemodialysis therapy. Antiplatelet agents may prevent…”
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Progression of Renal Impairment and Chronic Kidney Disease in Chronic Heart Failure: An Analysis From GISSI-HF by Damman, Kevin, MD, PhD, Masson, Serge, PhD, Lucci, Donata, MSc, Gorini, Marco, MS, Urso, Renato, PhD, Maggioni, Aldo P., MD, Tavazzi, Luigi, MD, Tarantini, Luigi, MD, Tognoni, Gianni, MD, Voors, Adriaan, MD, PhD, Latini, Roberto, MD

“…Highlights • The mean deterioration in estimated GFR in patients with chronic heart failure was 1.5 mL • min−1  • 1.73 m−2 in the first year, which can be…”
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Incidence of new-onset diabetes and impaired fasting glucose in patients with recent myocardial infarction and the effect of clinical and lifestyle risk factors by Mozaffarian, Dariush, Dr, Marfisi, RosaMaria, MS, Levantesi, Giacomo, MD, Silletta, Maria G, MS, Tavazzi, Luigi, MD, Tognoni, Gianni, MD, Valagussa, Franco, MD, Marchioli, Roberto, MD

“…Summary Background Individuals with diabetes are at higher risk of myocardial infarction than non-diabetics. However, much less is known about the incidence…”
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A meta-analysis of trials of pulmonary hypertension: A clinical condition looking for drugs and research methodology by Macchia, Alejandro, MD, Marchioli, Roberto, MD, Marfisi, RosaMaria, MS, Scarano, Marco, MS, Levantesi, Giacomo, MD, Tavazzi, Luigi, MD, Tognoni, Gianni, MD

“…Background Various innovative pharmacologic strategies for the treatment of patients with pulmonary hypertension have been tested in recent years. Neither…”
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Systematic review of trials using vasodilators in pulmonary arterial hypertension: Why a new approach is needed by Macchia, Alejandro, MD, Marchioli, Roberto, MD, Tognoni, Gianni, MD, Scarano, Marco, MS, Marfisi, RosaMaria, MS, Tavazzi, Luigi, MD, Rich, Stuart, MD

“…Background In a previous metaanalysis on the approved treatments for pulmonary hypertension, we reported that all therapies caused small changes in 6-minute…”
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Plasma n-3 polyunsaturated fatty acids in chronic heart failure in the GISSI-Heart Failure Trial: Relation with fish intake, circulating biomarkers, and mortality by Masson, Serge, PhD, Marchioli, Roberto, MD, Mozaffarian, Dariush, MD, Bernasconi, Roberto, Milani, Valentina, MS, Dragani, Luana, Tacconi, Mariateresa, PhD, Marfisi, Rosa Maria, MS, Borgese, Luisa, MD, Cirrincione, Vincenzo, MD, Febo, Oreste, MD, Nicolis, Enrico, MS, Maggioni, Aldo P., MD, Tognoni, Gianni, MD, Tavazzi, Luigi, MD, Latini, Roberto, MD

“…Background Treatment with long-chain n-3 polyunsaturated fatty acids (n-3 PUFAs) can improve clinical outcomes in patients with heart failure (HF). Circulating…”
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Noninvasive Ventilation in Acute Cardiogenic Pulmonary Edema: A Meta-Analysis of Randomized Controlled Trials by Mariani, Javier, MD, Macchia, Alejandro, MD, Belziti, César, MD, DeAbreu, Maximiliano, MD, Gagliardi, Juan, MD, Doval, Hernán, MD, Tognoni, Gianni, MD, Tajer, Carlos, MD

“…Abstract Background The evidence of individual studies in acute cardiogenic pulmonary edema (ACPE) supporting noninvasive ventilation (NIV) is still…”
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