Search Results - "Toet, K"

Fenofibrate Reduces Atherogenesis in ApoE3Leiden Mice: Evidence for Multiple Antiatherogenic Effects Besides Lowering Plasma Cholesterol by Kooistra, T, Verschuren, L, de Vries-van der Weij, J, Koenig, W, Toet, K, Princen, H M.G, Kleemann, R

“…OBJECTIVE—To demonstrate, quantify, and mechanistically dissect antiatherosclerotic effects of fenofibrate besides lowering plasma cholesterol per se. METHODS…”
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Human visceral adipose tissue and the plasminogen activator inhibitor type 1 by Lindeman, J.H.N, Pijl, H, Toet, K, Eilers, P.H.C, Ramshorst, B. van, Buijs, M.M, Bockel, J.H. van, Kooistra, T

“…The objective of this study was to systematically evaluate the molecular basis of the association between visceral fat mass and plasma plasminogen activator…”
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Stimulation of tissue-type plasminogen activator gene expression by sodium butyrate and trichostatin A in human endothelial cells involves histone acetylation by Arts, J, Lansink, M, Grimbergen, J, Toet, K H, Kooistra, T

“…We have previously shown that the pleiotropic agent sodium butyrate strongly stimulates tissue-type plasminogen activator (t-PA) expression in human umbilical…”
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Modulation of procoagulant and fibrinolytic system components of mesothelial cells by inflammatory mediators by Sitter, T, Toet, K, Fricke, H, Schiffl, H, Held, E, Kooistra, T

“…Human peritoneal mesothelial cells (HMC) play a critical role in maintaining the intraperitoneal balance between fibrinolysis and coagulation by expressing the…”
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MMP-9 Activity in Urine from Patients with Various Tumors, as Measured by a Novel MMP Activity Assay Using Modified Urokinase as a Substrate by HANEMAAIJER, R., SIER, C.F. M., VISSER, H., SCHOLTE, L., van LENT, N., HOEKMAN, K., VERHEIJEN, J. H.

“…Matrix metalloproteinases (MMPs) play an important role in many pathologic processes, but their activities are difficult to determine since no simple specific…”
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Characterization of Human Induced Pluripotent Stem Cell-Derived Hepatocytes with Mature Features and Potential for Modeling Metabolic Diseases by Holmgren, Gustav, Ulfenborg, Benjamin, Asplund, Annika, Toet, Karin, Andersson, Christian X, Hammarstedt, Ann, Hanemaaijer, Roeland, Küppers-Munther, Barbara, Synnergren, Jane

“…There is a strong anticipated future for human induced pluripotent stem cell-derived hepatocytes (hiPS-HEP), but so far, their use has been limited due to…”
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Stimulation of tissue-type plasminogen activator synthesis by retinoids in cultured human endothelial cells and rat tissues in vivo by Kooistra, T, Opdenberg, J P, Toet, K, Hendriks, H F, van den Hoogen, R M, Emeis, J J

“…Tissue-type plasminogen activator (t-PA) and its inhibitor, plasminogen activator inhibitor 1 (PAI-1), play an important role in regulating the fibrinolytic…”
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Adenovirus-mediated transfer of the 39 kD receptor-associated protein increases fibrinolytic capacity by Goedde, Martin F., Grimbergen, Jos M., Toet, Karin H., Sitter, Thomas, Quax, Paul H., Kooistra, Teake

“…Adenovirus-mediated transfer of the 39 kD receptor-associated protein increases fibrinolytic capacity. The mesothelium has an important role in maintaining an…”
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Hepatocyte transplantation into solid supports in the rhesus monkey: the influence of acidic fibroblast growth factor on prevascularization and hepatocyte survival by de Roos, W K, Borel Rinkes, I H, Minnee, P, Toet, K H, Bouwman, E, Kooistra, T, Valerio, D, Bruijn, J A, Terpstra, O T

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Physical stability and microstructure of concentrated dispersions of lamellar liquid-crystalline droplets containing nonionic surfactants in aqueous electrolyte solution by Schepers, F. J, Toet, W. K, Van de Pas, J. C

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Increased gelatinase‐A and gelatinase‐B activities in malignant vs. benign breast tumors by Hanemaaijer, Roeland, Verheijen, Jan H., Maguire, Teresa M., Visser, Hetty, Toet, Karin, McDermott, Enda, O'Higgins, Niall, Duffy, Michael J.

“…Matrix metalloproteinases (MMP) types 2 and 9 (also known as gelatinase A and B) are thought to be causally involved in cancer invasion and metastasis. In…”
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On the Role of c-Jun in the Induction of PAI-1 Gene Expression by Phorbol Ester, Serum, and IL-1 alpha in HepG2 Cells by Arts, Janine, Grimbergen, Jos, Toet, Karin, Kooistra, Teake

“…We have characterized the regulation of plasminogen activator inhibitor-1 (PAI-1) gene expression by phorbol 12-myristate 13-acetate (PMA), serum, and…”
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Fenofibrate reduces atherogenesis in AapoE3leiden mice : Evidence for multiple antiatherogenic effects besides lowering plasma cholesterol by KOOISTRA, T, VERSCHUREN, L, DE VRIES-VAN DER WEIJ, J, KOENIG, W, TOET, K, PRINCEN, H. M. G, KLEEMANN, R

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Fibrinolytic activity of human mesothelial cells is counteracted by rapid uptake of tissue-type plasminogen activator by Sitter, Thomas, Toet, Karin, Quax, Paul, Kooistra, Teake

“…Fibrinolytic activity of human mesothelial cells is counteracted by rapid uptake of tissue-type plasminogen activator. Human mesothelial cells (HMCs) have an…”
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On the role of c-Jun in the induction of PAI-1 gene expression by phorbol ester, serum, and IL-1alpha in HepG2 cells by Arts, J, Grimbergen, J, Toet, K, Kooistra, T

“…We have characterized the regulation of plasminogen activator inhibitor-1 (PAI-1) gene expression by phorbol 12-myristate 13-acetate (PMA), serum, and…”
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Increased Clearance Explains Lower Plasma Levels of Tissue-Type Plasminogen Activator by Estradiol: Evidence for Potently Enhanced Mannose Receptor Expression in Mice by Lansink, Mirian, Jong, Miek, Bijsterbosch, Martin, Bekkers, Marian, Toet, Karin, Havekes, Louis, Emeis, Jef, Kooistra, Teake

“…Several clinical studies have demonstrated an inverse relationship between circulating levels of estrogen and tissue-type plasminogen activator (t-PA). The…”
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Simvastatin suppresses tissue factor expression and increases fibrinolytic activity in tumor necrosis factor-α–activated human peritoneal mesothelial cells by Haslinger, Bettina, Kleemann, Robert, Toet, Karin H., Kooistra, Teake

“…Simvastatin suppresses tissue factor expression and increases fibrinolytic activity in tumor necrosis factor-α–activated human peritoneal mesothelial cells…”
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Leptin and the Proinflammatory State Associated with Human Obesity by Hukshorn, Chris J., Lindeman, Jan H. N., Toet, Karin H., Saris, Wim H. M., Eilers, Paul H. C., Westerterp-Plantenga, Margriet S., Kooistra, Teake

“…It has been suggested that elevated leptin levels underlie the low grade proinflammatory state in human obesity. We reasoned that if elevated leptin levels are…”
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Role of protein kinase C and cyclic adenosine monophosphate in the regulation of tissue-type plasminogen activator, plasminogen activator inhibitor-1, and platelet-derived growth factor mRNA levels in human endothelial cells. Possible involvement of proto-oncogenes c-jun and c-fos by Kooistra, T, Bosma, P J, Toet, K, Cohen, L H, Griffioen, M, van den Berg, E, le Clercq, L, van Hinsbergh, V W

“…Activation of protein kinase C leads to a strong induction of tissue-type plasminogen activator (t-PA) expression in endothelial cells. Using endothelial cells…”
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Simvastatin increases fibrinolytic activity in human peritoneal mesothelial cells independent of cholesterol lowering by Haslinger, Bettina, Goedde, Martin F., Toet, Karin H., Kooistra, Teake

“…Simvastatin increases fibrinolytic activity in human peritoneal mesothelial cells independent of cholesterol lowering. The continuous physical and chemical…”
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