Search Results - "Todokoro, K"

Activation of helix-loop-helix proteins Id1, Id2 and Id3 during neural differentiation by Nagata, Y, Todokoro, K

“…Id is a nuclear factor containing a helix-loop-helix (HLH) motif. It has been reported that Id functions as an inhibitor of cell differentiation and its gene…”
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Bone Marrow Stromal Cells Produce Thrombopoietin and Stimulate Megakaryocyte Growth and Maturation But Suppress Proplatelet Formation by Nagahisa, Hiroshi, Nagata, Yuka, Ohnuki, Toshio, Osada, Mizuho, Nagasawa, Toshiro, Abe, Tsukasa, Todokoro, Kazuo

“…Production of blood cells is regulated by the interplay of various cytokines and bone marrow stromal cells. Recently, a ligand for the orphan receptor Mpl was…”
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Down-Regulation of c-myb Gene Expression is a Prerequisite for Erythropoietin-Induced Erythroid Differentiation by Todokoro, Kazuo, Watson, Roger J., Higo, Hiromi, Amanuma, Hiroshi, Kuramochi, Satomi, Yanagisawa, Hiromi, Ikawa, Yoji

“…The role of nuclear protooncogenes during erythroid cell differentiation was examined by transfecting exogenous c-fos and c-myb genes into mouse…”
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Modulation of platelet activation in vitro by thrombopoietin by Kojima, H, Hamazaki, Y, Nagata, Y, Todokoro, K, Nagasawa, T, Abe, T

“…Effect of human recombinant thrombopoietin (TPO) on platelet activation in vitro was studied. Although TPO itself did not cause platelet aggregation, it…”
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Induction of Erythroid-Specific Gene Expression in Lymphoid Cells by Chiba, Tomoki, Nagata, Yuka, Kishi, Atsushi, Sakamaki, Kazuhiro, Miyajima, Atsushi, Yammoto, Masayuki, Engel, James D., Todokoro, Kazuo

“…Erythropoietin (Epo) is a cytokine which specifically regulates differentiation and proliferation of erythroid progenitor cells. We report here that Epo…”
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Specific Binding of Erythropoietin to Its Receptor on Responsive Mouse Erythroleukemia Cells by Todokoro, Kazuo, Kanazawa, Satoshi, Amanuma, Hiroshi, Ikawa, Yoji

“…Erythropoietin (Epo) is a glycoprotein factor that specifically regulates the proliferation and differentiation of erythroid progenitor cells. Here we describe…”
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Thrombopoietin Induces Megakaryocyte Differentiation in Hematopoietic Progenitor FDC-P2 Cells (∗) by Nagata, Yuka, Nagahisa, Hiroshi, Aida, Yoko, Okutomi, Keiichi, Nagasawa, Toshiro, Todokoro, Kazuo

“…Thrombopoietin (Tpo) is a cytokine that specifically regulates megakaryocyte maturation and platelet production. Little is known about the molecular and…”
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Activation of mitogen-activated protein kinase cascade through erythropoietin receptor by Todokoro, K, Sugiyama, M, Nishida, E, Nakaya, K

“…Erythropoietin is a cytokine which specifically regulates differentiation and proliferation of erythroid progenitor cells. We show here that binding of…”
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Phosphorylation of Helix-Loop-Helix Proteins Id1, Id2 and Id3 by Nagata, Y., Shoji, W., Obinata, M., Todokoro, K.

“…Id is a helix-loop-helix protein which forms heterodimer with ubiquitous and/or tissue-specific basic helix-loop-helix proteins and inhibits their DNA binding…”
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Ligand-dependent activation of chimeric receptors with the cytoplasmic domain of the interleukin-3 receptor beta subunit (beta IL3) by SAKAMAKI, K, HUEY-MEI WANG, MIYAJIMA, I, KITAMURA, T, TODOKORO, K, HARADA, N, MIYAJIMA, A

“…beta IL3 (formerly known as AIC2A), a beta subunit of the murine interleukin-3 receptor (IL-3R), is not only required for formation of the high affinity…”
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Essential roles of KIF4 and its binding partner PRC1 in organized central spindle midzone formation by Kurasawa, Yasuhiro, Earnshaw, William C, Mochizuki, Yuko, Dohmae, Naoshi, Todokoro, Kazuo

“…A number of proteins accumulate in the anaphase spindle midzone, but the interaction and precise role of these proteins in midzone organization remain obscure…”
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Structural relationship of human interferon alpha genes and pseudogenes by Henco, K, Brosius, J, Fujisawa, A, Fujisawa, J I, Haynes, J R, Hochstadt, J, Kovacic, T, Pasek, M, Schamböck, A, Schmid, J

“…We have isolated and characterized DNA segments containing IFN-alpha-related sequences from human lambda and cosmid clone banks. We describe six linkage groups…”
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Characterization of the Truncated Thrombopoietin Variants by Wada, T., Nagata, Y., Nagahisa, H., Okutomi, K., Ha, S.H., Ohnuki, T., Kanaya, T., Matsumura, M., Todokoro, K.

“…Thrombopoietin (Tpo) is a specific cytokine which regulates megakaryocyte differentiation and maturation. We isolated a truncated mouse Tpo cDNA, the product…”
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Requirement of Activation of JNK and p38 for Environmental Stress-Induced Erythroid Differentiation and Apoptosis and of Inhibition of ERK for Apoptosis by Nagata, Yuka, Todokoro, Kazuo

“…C-Jun amino terminal kinase/stress-activated protein kinases (JNK/SAPK) and p38 subgroups of mitogen-activated protein kinases have been suggested to play a…”
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Activation of p38 MAP Kinase and JNK But Not ERK Is Required for Erythropoietin-Induced Erythroid Differentiation by Nagata, Yuka, Takahashi, Noriko, Davis, Roger J., Todokoro, Kazuo

“…p38 MAP kinase (p38) and JNK have been described as playing a critical role in the response to a variety of environmental stresses and proinflammatory…”
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Transcription within a Functional Human Centromere by Saffery, Richard, Sumer, Huseyin, Hassan, Sara, Wong, Lee H., Craig, Jeffrey M., Todokoro, Kazuo, Anderson, Melissa, Stafford, Angela, Choo, K.H.Andy

“…Recent data in yeast and Drosophila suggest a domain-like centromere structure with a modified chromatin core and flanking regions of heterochromatin. We have…”
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Activation of p38 MAP kinase and JNK but not ERK is required for erythropoietin-induced erythroid differentiation by NAGATA, Y, TAKAHASHI, N, DAVIS, R. J, TODOKORO, K

“…p38 MAP kinase (p38) and JNK have been described as playing a critical role in the response to a variety of environmental stresses and proinflammatory…”
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CENP-H, a constitutive centromere component, is required for centromere targeting of CENP-C in vertebrate cells by Fukagawa, Tatsuo, Mikami, Yoshikazu, Nishihashi, Ai, Regnier, Vinciane, Haraguchi, Tokuko, Hiraoka, Yasushi, Sugata, Naoko, Todokoro, Kazuo, Brown, William, Ikemura, Toshimichi

“…CENP‐H has recently been discovered as a constitutive component of the centromere that co‐localizes with CENP‐A and CENP‐C throughout the cell cycle. The…”
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δ-Tubulin is a component of intercellular bridges and both the early and mature perinuclear rings during spermatogenesis by Kato, Akira, Nagata, Yuka, Todokoro, Kazuo

“…Mammalian spermatogenesis involves drastic morphological changes leading to the development of the mature sperm. Sperm development includes formation of the…”
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Two non‐allelic human interferon alpha genes with identical coding regions by Todokoro, K., Kioussis, D., Weissmann, C.

“…A hitherto undescribed human interferon‐alpha (IFN‐alpha) gene, IFN‐alpha 13, has been isolated and characterized. Its entire coding sequence is completely…”
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