Search Results - "Todhunter, R. J."

Technical note: Use of marker-based relationships with multiple-trait derivative-free restricted maximal likelihood by Zhang, Z, Todhunter, R.J, Buckler, E.S, Van Vleck, L.D

“…The widespread use of the set of multiple-trait derivative-free REML programs for prediction of breeding values and estimation of variance components has led…”
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Analysis of Allele Fidelity, Polymorphic Information Content, and Density of Microsatellites in a Genome-Wide Screening for Hip Dysplasia in a Crossbreed Pedigree by Mateescu, R. G, Zhang, Z, Tsai, K, Phavaphutanon, J, Burton-Wurster, N. I, Lust, G, Quaas, R, Murphy, K, Acland, G. M, Todhunter, R. J

“…Recent advances in genomics resources and tools are facilitating quantitative trait locus mapping. We developed a crossbreed pedigree for mapping quantitative…”
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Genes in Canine Articular Cartilage That Respond to Mechanical Injury: Gene Expression Studies With Affymetrix Canine GeneChip by Burton-Wurster, N, Mateescu, R. G, Todhunter, R. J, Clements, K. M, Sun, Q, Scarpino, V, Lust, G

“…The Affymetrix canine GeneChip with 23,836 probe sets was used to look for cartilage genes that are significantly altered in response to mechanical impact. The…”
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Experimental Lyme Disease in Dogs Produces Arthritis and Persistent Infection by Appel, Max J. G., Allan, Sandra, Jacobson, Richard H., Lauderdale, Tsai Ling, Chang, Yung Fu, Shin, Sang J., Thomford, John W., Todhunter, Rory J., Summers, Brian A.

“…Lyme disease was reproduced in specific pathogen-free beagle dogs by exposure to Borrelia burgdorferi-infected ticks (Ixodes dammini). Seroconversion and…”
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Genetic Structure of Susceptibility Traits for Hip Dysplasia and Microsatellite Informativeness of an Outcrossed Canine Pedigree by Todhunter, R. J., Bliss, S. P., Casella, G., Wu, R., Lust, G., Burton-Wurster, N. I., Williams, A. J., Gilbert, R. O., Acland, G. M.

“…An outcrossed canine pedigree was developed for quantitative trait locus (QTL) mapping of hip dysplasia by breeding dysplastic Labrador retrievers to…”
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outcrossed canine pedigree for linkage analysis of hip dysplasia by Todhunter, R.J, Acland, G.M, Olivier, M, Williams, A.J, Vernier-Singer, M, Burton-Wurster, N, Farese, J.P, Grohn, Y.T, Gilbert, R.O, Dykes, N.L

“…Canine hip dysplasia (CHD) is a prevalent, debilitating, polygenic disease characterized by hip subluxation and laxity which results in osteoarthritis. We are…”
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Immunohistochemical analysis of an equine model of synovitis-induced arthritis by Todhunter, P G, Kincaid, S A, Todhunter, R J, Kammermann, J R, Johnstone, B, Baird, A N, Hanson, R R, Wright, J M, Lin, H C, Purohit, R C

“…To use lipopolysaccharide (LPS) to create synovitis in the midcarpal joint of ponies, and to assess the morphologic, histochemical, and immunohistochemical…”
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Site-specific variation in femoral head cartilage composition in dogs at high and low risk for development of osteoarthritis: insights into cartilage degeneration by Burton-Wurster, N, Farese, J.P, Todhunter, R.J, Lust, G

“…Objective To determine which characteristics of cartilage lesion pathology are detected in dogs at high risk to develop osteoarthritis prior to diagnosis by…”
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Slow-acting, disease-modifying osteoarthritis agents by McNamara, P S, Johnston, S A, Todhunter, R J

“…There is evidence to suggest that tetracyclines have benefit beyond their antimicrobial activity. The ability to inhibit metalloproteinase activity may provide…”
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Repeatability of dorsolateral subluxation scores in dogs and correlation with macroscopic appearance of hip osteoarthritis by Lust, G, Todhunter, R J, Erb, H N, Dykes, N L, Williams, A J, Burton-Wurster, N I, Farese, J P

“…To determine whether dorsolateral subluxation (DLS) scores in young dogs could be used to reliably predict which dogs would develop evidence of hip…”
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Effects of exercise and polysulfated glycosaminoglycan on repair of articular cartilage defects in the equine carpus by Todhunter, R J, Minor, R R, Wootton, J A, Krook, L, Burton-Wurster, N, Lust, G

“…Our aim was to determine if mild to moderate postoperative exercise and intra-articular polysulfated glycosaminoglycan result in improved repair of large,…”
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Onset of epiphyseal mineralization and growth plate closure in radiographically normal and dysplastic Labrador retrievers by Todhunter, R J, Zachos, T A, Gilbert, R O, Erb, H N, Williams, A J, Burton-Wurster, N, Lust, G

“…To determine whether onset of mineralization of the femoral and proximal tibial epiphyses and age at closure of the femoral and acetabular triradiate growth…”
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Effect of methylprednisolone acetate on proteoglycan and collagen metabolism of articular cartilage explants by Todhunter, R J, Fubini, S L, Wootton, J A, Lust, G

“…The effect of different doses of methylprednisolone acetate (MPA) on proteoglycan and collagen metabolism of articular cartilage from normal equine joints was…”
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Polysulfated glycosaminoglycan in the treatment of osteoarthritis by Todhunter, R J, Lust, G

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Acceleration and balance in trotting dogs by Lee, D V, Bertram, J E, Todhunter, R J

“…During quadrupedal trotting, diagonal pairs of limbs are set down in unison and exert forces on the ground simultaneously. Ground-reaction forces on individual…”
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Cross-validation of cyanogen bromide-peptide ratios to measure the proportion of type II collagen in pepsin digests of equine articular cartilage, meniscus, and cartilage repair tissue by Todhunter, R J, Wootton, J A, Altman, N, Lust, G, Minor, R R

“…Collagen type I and type II were purified from equine flexor tendon and articular cartilage, respectively. Equal amounts of these collagens were cleaved with…”
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Effect of methylprednisolone and mechanical loading on canine articular cartilage in explant culture by Farquhar, Tony, Todhunter, Rory J., Fubini, Susan L., Burton-Wurster, Nancy, Lust, Georeg

“…The objective of this study was to assess the effect of mechanical load on articular cartilage after in vitro corticosteroid exposure. Canine humeral cartilage…”
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Comparison of the trotting gaits of Labrador Retrievers and Greyhounds by Bertram, J E, Lee, D V, Case, H N, Todhunter, R J

“…To compare the trotting gaits of Labrador Retrievers and Greyhounds to determine whether differences in locomotion are attributable to differences in their…”
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Biomechanical comparison of two plating techniques for fixation of acetabular osteotomies in dogs by Hardie, R.J, Bertram, J.E.A, Todhunter, R.J, Trotter, E.J

“…Objective— To compare the failure properties of a 5‐hole, 2.7‐mm curved acetabular plate (AP) to a 5‐hole, 3.5‐mm reconstruction plate (RP) when applied to…”
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Effect of intramuscularly administered polysulfated glycosaminoglycan on articular cartilage from equine joints injected with methylprednisolone acetate by Fubini, S L, Boatwright, C E, Todhunter, R J, Lust, G

“…Intra-articularly administered, long-acting corticosteroids are a beneficial treatment for many equine joint disorders because they alleviate inflammation and…”
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