Search Results - "Todeschini, R."

A similarity-based QSAR model for predicting acute toxicity towards the fathead minnow (Pimephales promelas) by Cassotti, M., Ballabio, D., Todeschini, R., Consonni, V.

“…REACH regulation demands information about acute toxicity of chemicals towards fish and supports the use of QSAR models, provided compliance with OECD…”
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Epithelial Mesenchymal Transition Induces Aberrant Glycosylation through Hexosamine Biosynthetic Pathway Activation by Lucena, Miguel C., Carvalho-Cruz, Patricia, Donadio, Joana L., Oliveira, Isadora A., de Queiroz, Rafaela M., Marinho-Carvalho, Monica M., Sola-Penna, Mauro, de Paula, Iron F., Gondim, Katia C., McComb, Mark E., Costello, Catherine E., Whelan, Stephen A., Todeschini, Adriane R., Dias, Wagner B.

“…Deregulated cellular metabolism is a hallmark of tumors. Cancer cells increase glucose and glutamine flux to provide energy needs and macromolecular synthesis…”
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Sensitivity assessment of freshwater macroinvertebrates to pesticides using biological traits by Ippolito, A., Todeschini, R., Vighi, M.

“…Assessing the sensitivity of different species to chemicals is one of the key points in predicting the effects of toxic compounds in the environment…”
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Increase of O-glycosylated oncofetal fibronectin in high glucose-induced epithelial-mesenchymal transition of cultured human epithelial cells by Alisson-Silva, Frederico, Freire-de-Lima, Leonardo, Donadio, Joana L, Lucena, Miguel C, Penha, Luciana, Sá-Diniz, Julliana N, Dias, Wagner B, Todeschini, Adriane R

“…Growing evidences indicate that aberrant glycosylation can modulate tumor cell invasion and metastasis. The process termed "epithelial-mesenchymal transition"…”
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Hyperglycemia alters N-glycans on colon cancer cells through increased production of activated monosaccharides by Loponte, H. F., Oliveira, I. A., Rodrigues, B. C., Nunes-da-Fonseca, R., Mohana-Borges, R., Alisson-Silva, F., Dias, W. B., Todeschini, A. R.

“…Diabetes Mellitus (DM) is both, correlated and a known risk factor for colorectal cancer (CRC). Besides favoring the incidence of CRC, DM also accelerates its…”
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Hyperglycemia exacerbates colon cancer malignancy through hexosamine biosynthetic pathway by Vasconcelos-dos-Santos, A, Loponte, H F B R, Mantuano, N R, Oliveira, I A, de Paula, I F, Teixeira, L K, de-Freitas-Junior, J C M, Gondim, K C, Heise, N, Mohana-Borges, R, Morgado-Díaz, J A, Dias, W B, Todeschini, A R

“…Hyperglycemia is a common feature of diabetes mellitus, considered as a risk factor for cancer. However, its direct effects in cancer cell behavior are…”
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Experiments and numerical simulations of nonlinear vibration responses of an assembly with friction joints – Application on a test structure named “Harmony” by Claeys, M., Sinou, J-J., Lambelin, J-P., Todeschini, R.

“…In presence of friction, the frequency response function of a metallic assembly is strongly dependent on the excitation level. The local stick-slip behavior at…”
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Trends in Nanomedicines for Cancer Treatment by do Nascimento, Tatielle, Todeschini, Adriane R, Santos-Oliveira, Ralph, de Souza de Bustamante Monteiro, Mariana S, de Souza, Vilênia T, Ricci-Júnior, Eduardo

“…Cancer is characterized by abnormal cell growth and considered one of the leading causes of death around the world. Pharmaceutical Nanotechnology has been…”
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Reshaped Sequential Replacement for variable selection in QSPR: comparison with other reference methods by Grisoni, F., Cassotti, M., Todeschini, R.

“…The objective of the present work was to compare the Reshaped Sequential Replacement (RSR) algorithm with other well‐known variable selection techniques in the…”
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Modal interactions due to friction in the nonlinear vibration response of the “Harmony” test structure: Experiments and simulations by Claeys, M., Sinou, J-J., Lambelin, J-P., Todeschini, R.

“…The nonlinear vibration response of an assembly with friction joints – named “Harmony” – is studied both experimentally and numerically. The experimental…”
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K-CM: A new artificial neural network. Application to supervised pattern recognition by Buscema, M., Consonni, V., Ballabio, D., Mauri, A., Massini, G., Breda, M., Todeschini, R.

“…Artificial neural networks can be currently considered as one of the most important emerging tools in multivariate analysis due to their ability to deal with…”
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CD43 sialoglycoprotein modulates cardiac inflammation and murine susceptibility to Trypanosoma cruzi infection by Alisson-Silva, Frederico, Mantuano, Natália Rodrigues, Lopes, Ana Luiza, Vasconcelos-dos-Santos, Andréia, Vale, André Macedo, Costa, Miriam Maria, Cannon, Judy L., Oliveira, Ana Carolina, Todeschini, Adriane R.

“…CD43 (leukosialin) is a large sialoglycoprotein abundantly expressed on the surface of most cells from the hematopoietic lineage. CD43 is directly involved in…”
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Evidences for the involvement of cell surface glycans in stem cell pluripotency and differentiation by Alisson-Silva, Frederico, de Carvalho Rodrigues, Deivid, Vairo, Leandro, Asensi, Karina Dutra, Vasconcelos-dos-Santos, Andréia, Mantuano, Natalia Rodrigues, Dias, Wagner Barbosa, Rondinelli, Edson, Goldenberg, Regina Coeli dos Santos, Urmenyi, Turán Peter, Todeschini, Adriane R

“…Induced pluripotent stem (iPS) cells are somatic cells that have been reprogrammed to a pluripotent state via the introduction of defined transcription…”
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Ongoing outbreak of visceral leishmaniasis in Bologna Province, Italy, November 2012 to May 2013 by Varani, S, Cagarelli, R, Melchionda, F, Attard, L, Salvadori, C, Finarelli, A C, Gentilomi, G A, Tigani, R, Rangoni, R, Todeschini, R, Scalone, A, Di Muccio, T, Gramiccia, M, Gradoni, L, Viale, P, Landini, M P

“…An increased number of autochthonous visceral leishmaniasis (VL) cases has recently been reported in Bologna Province in northern Italy. Over six months from…”
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The K correlation index: theory development and its application in chemometrics by Todeschini, R., Consonni, V., Maiocchi, A.

“…A previous paper introduced a new correlation index, K, and tested it to evaluate the correlation content of a set of multivariate data. This paper presents an…”
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Phase II study of eribulin in combination with gemcitabine for the treatment of patients with locally advanced or metastatic triple negative breast cancer (ERIGE trial). Clinical and pharmacogenetic results on behalf of the Gruppo Oncologico Italiano di Ricerca Clinica (GOIRC) by Pellegrino, B., Cavanna, L., Boggiani, D., Zamagni, C., Frassoldati, A., Schirone, A., Caldara, A., Rocca, A., Gori, S., Piacentini, F., Berardi, R., Brandes, A.A., Foglietta, J., Villa, F., Todeschini, R., Tognetto, M., Naldi, N., Bortesi, B., Montemurro, F., Ardizzoni, A., Boni, L., Musolino, A.

“…The combination of a microtubule inhibitor (eribulin) with a nucleoside analog (gemcitabine) may synergistically induce tumor cell death, particularly in…”
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Data correlation, number of significant principal components and shape of molecules. The K correlation index by Todeschini, R.

“…Data correlation is an old great problem in multivariate analysis. In this paper a new correlation index, called K, is proposed to evaluate the correlation…”
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A similarity-based QSAR model for predicting acute toxicity towards the fathead minnow (Pimephales promelas) by Cassotti, M, Ballabio, D, Todeschini, R, Consonni, V

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Canonical Measure of Correlation ( CMC) and Canonical Measure of Distance ( CMD) between sets of data. Part 1. Theory and simple chemometric applications by Todeschini, R., Ballabio, D., Consonni, V., Manganaro, A., Mauri, A.

“…So far, similarity/diversity of objects has been widely studied in different research fields and a number of distance measures to estimate diversity between…”
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Further structural characterization of the Echinococcus granulosus laminated layer carbohydrates: the blood-antigen P1-motif gives rise to branches at different points of the O-glycan chains by Lin, Gerardo, Todeschini, Adriane R, Koizumi, Akihiko, Neves, Jorge L, González, Humberto, Dematteis, Sylvia, Hada, Noriyasu, Previato, Jose O, Ferreira, Fernando, Mendonça-Previato, Lucia, Díaz, Alvaro

“…The glycobiology of the cestodes, a class of parasitic flatworms, is still largely unexplored. An important cestode species is Echinococcus granulosus, the…”
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