Diagnosis of dermatomyositis and polymyositis: a study of 102 cases

Patients with dermatomyositis (DM) or polymyositis (PM) were studied retrospectively. The patients were divided into four groups: definite PM 24, probable PM 19, definite DM 34 and mild-early DM 25 cases. PM patients complained more often proximal muscle weakness [p <0.01]. DM patients complained...

Full description

Saved in:

Bibliographic Details
Published in:	Arquivos de neuro-psiquiatria Vol. 58; no. 3B; pp. 789 - 799
Main Authors:	Scola, R H, Werneck, L C, Prevedello, D M, Toderke, E L, Iwamoto, F M
Format:	Journal Article
Language:	English
Published:	Brazil Academia Brasileira de Neurologia - ABNEURO 01-09-2000 Academia Brasileira de Neurologia (ABNEURO)
Subjects:	Adolescent Adult Aged Aged, 80 and over Alanine Transaminase - blood Biopsy Blood Sedimentation Child Child, Preschool Creatine Kinase - blood dermatomyositis Dermatomyositis - blood Dermatomyositis - complications Dermatomyositis - diagnosis diagnosis Electromyography Female Humans Infant Infant, Newborn inflammatory myopathy Male Middle Aged NEUROSCIENCES polymyositis Polymyositis - blood Polymyositis - complications Polymyositis - diagnosis PSYCHIATRY Retrospective Studies miopatia inflamatória dermatomiosite polimiosite polymyositis diagnosis dermatomyositis diagnóstico inflammatory myopathy
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	Patients with dermatomyositis (DM) or polymyositis (PM) were studied retrospectively. The patients were divided into four groups: definite PM 24, probable PM 19, definite DM 34 and mild-early DM 25 cases. PM patients complained more often proximal muscle weakness [p <0.01]. DM patients complained more arthralgia [p <0.05], dysphagia [p <0.03] and weight loss [p <0.04]. Five patients had a malignant neoplasm and 9 had other connective-tissue disease. DM presented higher ESR than PM [p <0.002]. PM presented more significant increase in creatine kinase (CK) [p <0.02] and in alanine aminotransferase (ALT) [p <0.001] levels. Electromyography showed myopathic pattern in 76%. Muscle biopsy was the definitive test. Perifascicular atrophy was more frequent in definite DM than in mild-early DM group [p <0.03]. A small association with connective-tissue diseases and neoplasms was found. DM and PM are clinically different. DM presents systemic involvement affecting the skin, developing more severe arthralgia, dysphagia and weight loss and presenting higher values of ESR. PM presents a restricted and more significant involvement of muscles generating more weakness complaints and higher levels of serum muscle enzymes.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0004-282X 1678-4227 0004-282X 1678-4227
DOI:	10.1590/s0004-282x2000000500001