Search Results - "Todd, R F"
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Dose Escalation in Non–Small-Cell Lung Cancer Using Three-Dimensional Conformal Radiation Therapy: Update of a Phase I Trial
Published in Journal of clinical oncology (01-01-2001)“…High-dose radiation may improve outcomes in non-small-cell lung cancer (NSCLC). By using three-dimensional conformal radiation therapy and limiting the target…”
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2
Expression and colocalization of cytokeratin 1 and urokinase plasminogen activator receptor on endothelial cells
Published in Blood (15-04-2001)“…The cellular localization of human cytokeratin 1 (CK1), urokinase plasminogen activator receptor (uPAR), and gC1qR, high-molecular-weight kininogen…”
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3
The urokinase receptor (CD87) facilitates CD11b/CD18-mediated adhesion of human monocytes
Published in The Journal of clinical investigation (15-04-1996)“…Urokinase receptors (uPAR; CD87) from complexes with complement receptor 3 (CR3) (CD11b/CD18), a beta2 integrin. In this study, we sought to determine if this…”
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4
The urokinase receptor is required for human monocyte chemotaxis in vitro
Published in The Journal of clinical investigation (01-04-1994)“…Mononuclear phagocytes (Mphi) produce urokinase-type plasminogen activator (uPA) and also express a specific cell-surface receptor for urokinase, uPAR. The…”
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5
Physical association of complement receptor type 3 and urokinase-type plasminogen activator receptor in neutrophil membranes
Published in The Journal of immunology (1950) (01-05-1994)“…A previous study has shown that Fc gamma RIIIB (CD16), an extensively glycosylated glycosyl-phosphatidylinositol-linked neutrophil membrane protein,…”
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6
Anti-CD11b monoclonal antibody reduces ischemic cell damage after transient focal cerebral ischemia in rat
Published in Annals of neurology (01-04-1994)“…We investigated the effect of an anti-CD11b monoclonal antibody (1B6c) on ischemic cell damage after transient middle cerebral artery occlusion. We divided…”
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Regulation of Transendothelial Neutrophil Migration by Endogenous Interleukin-8
Published in Science (American Association for the Advancement of Science) (04-10-1991)“…Movement of neutrophils from the bloodstream to inflamed tissue depends on the activation of both the neutrophil and the endothelial cell. Endothelial cells…”
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Molecular Determinants of Reperfusion-Induced Leukocyte Adhesion and Vascular Protein Leakage
Published in Circulation research (01-02-1994)“…The adherence and emigration of leukocytes have been implicated as a rate-limiting step in the microvascular dysfunction associated with reperfusion of…”
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Aberrant Neutrophil Trafficking and Metabolic Oscillations in Severe Pyoderma Gangrenosum
Published in Journal of investigative dermatology (01-08-1998)“…Having previously associated metabolic oscillations with cell locomotion, we hypothesized that patients with abnormalities in neutrophil trafficking may…”
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Journal Article Conference Proceeding -
10
The urokinase receptor is expressed in invasive breast cancer but not in normal breast tissue
Published in Cancer research (Chicago, Ill.) (15-02-1994)“…We have studied expression of the urokinase receptor (u-PAR) in paraffin-embedded breast tissues at various stages of malignant progression. Forty-nine of 59…”
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Urokinase receptor. An activation antigen in human T lymphocytes
Published in The Journal of immunology (1950) (15-01-1994)“…The ability of activated T lymphocytes to extravasate and reach inflammatory and malignant foci in the tissues is a basic function of cellular immunity. Recent…”
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12
Expression of immunologically relevant endothelial cell activation antigens on isolated central nervous system microvessels from patients with multiple sclerosis
Published in Annals of neurology (01-01-1994)“…Activation of the vascular endothelium is thought to be an important facet of inflammation, thrombosis, and vasculitis. Activated endothelial cells express a…”
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13
Clustering of Urokinase Receptors (uPAR; CD87) Induces Proinflammatory Signaling in Human Polymorphonuclear Neutrophils
Published in The Journal of immunology (1950) (15-09-2000)“…Leukocytes use urokinase receptors (uPAR; CD87) in adhesion, migration, and proteolysis of matrix proteins. Typically, uPAR clusters at cell-substratum…”
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14
Distinct Cellular Interactions of Secreted and Transmembrane Ebola Virus Glycoproteins
Published in Science (American Association for the Advancement of Science) (13-02-1998)“…The mechanisms by which Ebola virus evades detection and infects cells to cause hemorrhagic fever have not been defined, though its glycoprotein, synthesized…”
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15
Cocapping of the leukoadhesin molecules complement receptor type 3 and lymphocyte function-associated antigen-1 with Fc gamma receptor III on human neutrophils. Possible role of lectin-like interactions
Published in The Journal of immunology (1950) (01-04-1993)“…We have tested the possible physical interactions between the iC3b receptor (CR3), lymphocyte function-associated Ag-1, and class III Fc gamma receptor (Fc…”
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16
Reduction of experimental canine myocardial reperfusion injury by a monoclonal antibody (anti-Mo1, anti-CD11b) that inhibits leukocyte adhesion
Published in The Journal of clinical investigation (01-02-1988)“…A monoclonal antibody (904) that binds to a leukocyte cell adhesion-promoting glycoprotein, (Mo1; CD11b/CD18) was administered (1 mg/kg, iv.) to open chest…”
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Ebola virus secretory glycoprotein (sGP) diminishes Fc gamma RIIIB-to-CR3 proximity on neutrophils
Published in The Journal of immunology (1950) (15-01-2000)“…Previous studies have shown that Ebola virus' secretory glycoprotein (sGP) binds to Fc gamma RIIIB (CD16b) and inhibits L-selectin shedding. In this study, we…”
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18
LPS induces CD14 association with complement receptor type 3, which is reversed by neutrophil adhesion
Published in The Journal of immunology (1950) (15-01-1996)“…CD14, a glycosylphosphatidyl inositol (GPI)-linked membrane protein, is a key membrane binding site for LPS (endotoxin). Although CD14 lacks transmembrane and…”
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19
Function of the urokinase receptor (CD87) in neutrophil chemotaxis
Published in Journal of leukocyte biology (01-11-1995)“…During recruitment, leukocytes respond to chemotaxins and traverse matrix barriers. Urokinase-type plasminogen activator (uPA), bound to its receptor (uPAR;…”
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Reconstitution of antibody-dependent phagocytosis in fibroblasts expressing Fc gamma receptor IIIB and the complement receptor type 3
Published in The Journal of immunology (1950) (15-08-1994)“…In this study, we test the hypothesis that co-expression of both the complement receptor type 3 (CR3; CD11b/CD18) and Fc gamma receptor type IIIB (Fc gamma…”
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