Search Results - "Todd, Kennedi"

Aducanumab anti-amyloid immunotherapy induces sustained microglial and immune alterations by Cadiz, Mika P, Gibson, Katelin A, Todd, Kennedi T, Nascari, David G, Massa, Nashali, Lilley, Meredith T, Olney, Kimberly C, Al-Amin, Md Mamun, Jiang, Hong, Holtzman, David M, Fryer, John D

“…Aducanumab, an anti-amyloid immunotherapy for Alzheimer's disease, efficiently reduces Aβ, though its plaque clearance mechanisms, long-term effects, and…”
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Commonly disrupted pathways in brain and kidney in a pig model of systemic endotoxemia by Olney, Kimberly C, de Ávila, Camila, Todd, Kennedi T, Tallant, Lauren E, Barnett, J Hudson, Gibson, Katelin A, Hota, Piyush, Pandiane, Adithya Shyamala, Durgun, Pinar Cay, Serhan, Michael, Wang, Ran, Lind, Mary Laura, Forzani, Erica, Gades, Naomi M, Thomas, Leslie F, Fryer, John D

“…Sepsis is a life-threatening state that arises due to a hyperactive inflammatory response stimulated by infection and rarely other insults (e.g.,…”
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Widespread choroid plexus contamination in sampling and profiling of brain tissue by Olney, Kimberly C., Todd, Kennedi T., Pallegar, Praveen N., Jensen, Tanner D., Cadiz, Mika P., Gibson, Katelin A., Barnett, Joseph H., de Ávila, Camila, Bouchal, Samantha M., Rabichow, Benjamin E., Ding, Zonghui, Wojtas, Aleksandra M., Wilson, Melissa A., Fryer, John D.

“…The choroid plexus, a tissue responsible for producing cerebrospinal fluid, is found predominantly in the lateral and fourth ventricles of the brain. This…”
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Transcriptional Heterogeneity Overcomes Super-Enhancer Disrupting Drug Combinations in Multiple Myeloma by Welsh, Seth J, Barwick, Benjamin G, Meermeier, Erin W, Riggs, Daniel L, Shi, Chang-Xin, Zhu, Yuan Xiao, Sharik, Meaghen E, Du, Megan T, Abrego Rocha, Leslie D, Garbitt, Victoria M, Stein, Caleb K, Petit, Joachim L, Meurice, Nathalie, Tafoya Alvarado, Yuliza, Fonseca, Rodrigo, Todd, Kennedi T, Brown, Sochilt, Hammond, Zachery J, Cuc, Nicklus H, Wittenberg, Courtney, Herzog, Camille, Roschke, Anna V, Demchenko, Yulia N, Chen, Wei-Dong D, Li, Peng, Liao, Wei, Leonard, Warren J, Lonial, Sagar, Bahlis, Nizar J, Neri, Paola, Boise, Lawrence H, Chesi, Marta, Bergsagel, P Leif

“…Multiple myeloma (MM) is a malignancy that is often driven by MYC and that is sustained by IRF4, which are upregulated by super-enhancers. IKZF1 and IKZF3 bind…”
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Abstract 5630: Anti-BCMA bispecific tool therapy against VkMYC multiple myeloma is enhanced by IMiDs by Meermeier, Erin W., Sharik, Meaghen E., Welsh, Seth J., Stein, Caleb K., Garbitt, Victoria M., Brown, Sochilt, Todd, Kennedi T., Bergsagel, Marco, Bergsagel, P. Leif, Chesi, Marta

“…Abstract BCMA is an ideal target antigen for myeloma immunotherapy as it is specifically expressed by plasma cells and T cell-engaging, BCMA-bispecific…”
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Regulation of meningeal lymphatic function by APOE by DELIVANOGLOU, NIKOLETA, Todd, Kennedi, Barber, Megan J, Neves, Sofia Pereira, Schrader, Racquelle, Sanchez, Guadalupe, Rego, Shanon, Martens, Yuka A, Bu, Guojun, Fryer, John D., Mesquita, Sandro Gabriel (Sandro Da Mesquita) Ferreira Da

“…Background The meningeal layers form a unique interface between the central nervous and peripheral immune systems. The lymphatic vasculature that is present in…”
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IMiDs Synergize with EP300 Inhibition to Disrupt the Ikzf/MYC/IRF4 Axis in Multiple Myeloma by Welsh, Seth J, Barwick, Benjamin G, Meermeier, Erin, Riggs, Daniel, Shi, Chang-Xin, Zhu, Yuan Xiao, Sharik, Meaghen E, Du, Megan T, Garbitt, Victoria Marie, Stein, Caleb K, Petit, Joachim L, Meurice, Nathalie, Fonseca, Rodrigo, Todd, Kennedi, Brown, Sochilt, Tafoya Alvarado, Yuliza, Hammond, Zachary, Cuc, Nicklus, Wittenberg, Courtney, Herzog, Camille, Boise, Lawrence H., Bahlis, Nizar J., Neri, Paola, Kuehl, W. Michael, Chesi, Marta, Bergsagel, P. Leif

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Disrupting Ectopic Super-Enhancers to Treat Multiple Myeloma by Welsh, Seth, Riggs, Daniel, Meermeier, Erin, Shi, Chang-Xin, Garbitt, Victoria, Sharik, Meaghen E, Du, Megan, Todd, Kennedi, Hammond, Zachary, Brown, Sochilt, Stein, Caleb K, Neri, Paola, Bahlis, Nizar J., Barwick, Benjamin G, Boise, Larry H., Kuehl, W. Michael, Chesi, Marta, Bergsagel, P. Leif

“…Multiple myeloma (MM) is an incurable form of plasma cell cancer in which primary and secondary chromosomal translocations routinely juxtapose oncogenes to…”
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P-177 Transcriptional heterogeneity overcomes super-enhancer disrupting drug combinations in multiple myeloma (MM) by Welsh, Seth, Barwick, Benjamin, Meermeier, Erin, Riggs, Daniel, Shi, Chang-Xin, Sharik, Meaghen, Du, Megan, Rocha, Leslie Abrego, Garbitt, Victoria, Stein, Caleb, Petit, Joachim, Yuliza, Fonseca, Rodrigo, Todd, Kennedi, Brown, Sochilt, Leonard, Warren, Lonial, Sagar, Bahlis, Nizar, Neri, Paola, Kuehl, W. Michael, Boise, Lawrence, Chesi, Marta, Bergsagel, Leif

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