Search Results - "Todd, K.G"

Biomaterials and glia: Progress on designs to modulate neuroinflammation by Tsui, C., Koss, K., Churchward, M.A., Todd, K.G.

“…[Display omitted] Microglia are multi-functional cells that play a vital role in establishing and maintaining the function of the nervous system and…”
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Brain biocompatibility and microglia response towards engineered self-assembling (RADA)4 nanoscaffolds by Koss, K.M., Churchward, M.A., Nguyen, A.T., Yager, J.Y., Todd, K.G., Unsworth, L.D.

“…[Display omitted] (RADA)4-based nanoscaffolds have many inherent properties making them amenable to tissue engineering applications: ease of synthesis, ease of…”
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Fluoxetine and citalopram decrease microglial release of glutamate and d-serine to promote cortical neuronal viability following ischemic insult by Dhami, K.S., Churchward, M.A., Baker, G.B., Todd, K.G.

“…Depression is one of the most common disorders appearing following a stroke, and is also a major factor limiting recovery and rehabilitation in stroke…”
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Distinct activation profiles in microglia of different ages: A systematic study in isolated embryonic to aged microglial cultures by Lai, A.Y, Dibal, C.D, Armitage, G.A, Winship, I.R, Todd, K.G

“…Highlights • Basal and ATP-activated phenotypes of microglia vary non-linearly with age. • Neurotoxicity and production of microglial effectors are highest in…”
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Inhibition of β-amyloid1-42 internalization attenuates neuronal death by stabilizing the endosomal-lysosomal system in rat cortical cultured neurons by Song, M.S, Baker, G.B, Todd, K.G, Kar, S

“…Abstract A number of recent studies have indicated that accumulation of β amyloid (Aβ) peptides within neurons is an early event which may trigger degeneration…”
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Evaluation of the Role of NMDA-Mediated Excitotoxicity in the Selective Neuronal Loss in Experimental Wernicke Encephalopathy by Todd, K.G., Butterworth, R.F.

“…The goal of the studies described was to evaluate the role of NMDA receptor-mediated glutamate excitotoxicity in the pathogenesis of selective neuronal loss…”
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Supporting microglial niches for therapeutic benefit in psychiatric disorders by Churchward, M.A., Michaud, E.R., Todd, K.G.

“…Inflammation is an essential tissue response to injury, stress, or infection resulting in debris and/or pathogen clearance intended to promote healing and…”
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N-methyl,N-propargyl-2-phenylethylamine (MPPE), an analog of deprenyl, increases neuronal cell survival in thiamin deficiency encephalopathy by Kwan, E., Baker, G.B., Shuaib, A., Ling, L., Todd, K.G.

“…Wernicke encephalopathy (WE) is a neurological disorder attributable to thiamin deficiency (TD). Severe TD, in humans and animals, results in highly selective…”
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Inhibition of β-amyloid 1-42 internalization attenuates neuronal death by stabilizing the endosomal-lysosomal system in rat cortical cultured neurons by Song, M.S., Baker, G.B., Todd, K.G., Kar, S.

“…A number of recent studies have indicated that accumulation of β amyloid (Aβ) peptides within neurons is an early event which may trigger degeneration of…”
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A comparison of ventral tegmental neurons projecting to optic flow regions of the inferior olive vs. the hippocampal formation by Winship, I.R., Pakan, J.M.P., Todd, K.G., Wong-Wylie, D.R.

“…The ventral tegmental area (catecholaminergic group A10) is a midbrain region characterized by concentrated dopaminergic immunoreactivity. Previous studies in…”
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