Search Results - "Todd, Elizabeth"

Novel Mouse Model Reveals That Serine Phosphorylation of L-Plastin Is Essential for Effective Splenic Clearance of Pneumococcus by Anaya, Edgar P, Lin, Xue, Todd, Elizabeth M, Szasz, Taylor P, Morley, S Celeste

“…Asplenia imparts susceptibility to life-threatening sepsis with encapsulated bacteria, such as the pneumococcus. However, the cellular components within the…”
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Alveolar macrophage development in mice requires L-plastin for cellular localization in alveoli by Todd, Elizabeth M., Zhou, Julie Y., Szasz, Taylor P., Deady, Lauren E., D'Angelo, June A., Cheung, Matthew D., Kim, Alfred H.J., Morley, Sharon Celeste

“…Alveolar macrophages are lung-resident sentinel cells that develop perinatally and protect against pulmonary infection. Molecular mechanisms controlling…”
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L-plastin enhances NLRP3 inflammasome assembly and bleomycin-induced lung fibrosis by Joshi, Hemant, Almgren-Bell, Alison, Anaya, Edgar P., Todd, Elizabeth M., Van Dyken, Steven J., Seth, Anushree, McIntire, Katherine M., Singamaneni, Srikanth, Sutterwala, Fayyaz, Morley, Sharon C.

“…Macrophage adhesion and stretching have been shown to induce interleukin (IL)-1β production, but the mechanism of this mechanotransduction remains unclear…”
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LRRK1 regulation of actin assembly in osteoclasts involves serine 5 phosphorylation of L‐plastin by Si, Mingjue, Goodluck, Helen, Zeng, Canjun, Pan, Songqin, Todd, Elizabeth M., Morley, Sharon Celeste, Qin, Xuezhong, Mohan, Subburaman, Xing, Weirong

“…Mice with disruption of Lrrk1 and patients with nonfunctional mutant Lrrk1 exhibit severe osteopetrosis phenotypes because of osteoclast cytoskeletal…”
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Safe use of paracetamol and high-dose NSAID analgesia in dentistry during the COVID-19 pandemic by Crighton, Alexander J., McCann, Catherine T., Todd, Elizabeth J., Brown, Alyson J.

“…With dental services currently altered, dentists are being asked to provide advice, analgesia and antibiotics in situations where they would normally be…”
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Klebsiella pneumoniae FimK Promotes Virulence in Murine Pneumonia by Rosen, David A., Hilliard, Julia K., Tiemann, Kristin M., Todd, Elizabeth M., Morley, S. Celeste, Hunstad, David A.

“…Klebsiella pneumoniae, a chief cause of nosocomial pneumonia, is a versatile and commonly multidrug-resistant human pathogen for which further insight into…”
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Novel coenzyme Q6 genetic variant increases susceptibility to pneumococcal disease by Walker, Emma C., Javati, Sarah, Todd, Elizabeth M., Matlam, John-Paul, Lin, Xue, Bryant, Michelle, Krone, Emily, Ramani, Rashmi, Chandra, Pallavi, Green, Taylor P., Anaya, Edgar P., Zhou, Julie Y., Alexander, Katherine A., Tong, R. Spencer, Yuasi, Lapule, Boluarte, Sebastian, Yang, Fan, Greenberg, Lina, Nerbonne, Jeanne M., Greenberg, Michael J., Clemens, Regina A., Philips, Jennifer A., Wilson, Leslie D., Halabi, Carmen M., DeBosch, Brian J., Blyth, Christopher C., Druley, Todd E., Kazura, James W., Pomat, William S., Morley, Sharon Celeste

“…Acute lower respiratory tract infection (ALRI) remains a major worldwide cause of childhood mortality, compelling innovation in prevention and treatment…”
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The actin-bundling protein L-plastin is essential for marginal zone B cell development by Todd, Elizabeth M, Deady, Lauren E, Morley, Sharon Celeste

“…B cell development is exquisitely sensitive to location within specialized niches in the bone marrow and spleen. Location within these niches is carefully…”
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Intrinsic T‐ and B‐cell defects impair T‐cell‐dependent antibody responses in mice lacking the actin‐bundling protein L‐plastin by Todd, Elizabeth M., Deady, Lauren E., Morley, Sharon Celeste

“…Germinal center development, critical for long‐term humoral immunity, requires the trafficking of T and B lymphocytes to defined tissues and locations after…”
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Mst1 Kinase Regulates the Actin-Bundling Protein L-Plastin To Promote T Cell Migration by Xu, Xiaolu, Wang, Xinxin, Todd, Elizabeth M, Jaeger, Emily R, Vella, Jennifer L, Mooren, Olivia L, Feng, Yunfeng, Hu, Jiancheng, Cooper, John A, Morley, Sharon Celeste, Huang, Yina H

“…Exploring the mechanisms controlling lymphocyte trafficking is essential for understanding the function of the immune system and the pathophysiology of…”
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L-Plastin promotes podosome longevity and supports macrophage motility by Zhou, Julie Y., Szasz, Taylor P., Stewart-Hutchinson, Phillip J., Sivapalan, Janardan, Todd, Elizabeth M., Deady, Lauren E., Cooper, John A., Onken, Michael D., Morley, S. Celeste

“…•Podosome duration is reduced in the absence of l-plastin.•Resident peritoneal macrophages from l-plastin−/− mice do not polarize.•Efficient migration of…”
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Colonization with 19F and other pneumococcal conjugate vaccine serotypes in children in St. Louis, Missouri, USA by McFarland, Michelle, Szasz, Taylor P., Zhou, Julie Y., Motley, Kara, Sivapalan, Janardan S., Isaacson-Schmid, Megan, Todd, Elizabeth M., Hogan, Patrick G., Fritz, Stephanie A., Burnham, Carey-Ann D., Hoffmann, Steen, Morley, Sharon Celeste

“…•Prevalence of pneumococcal nasopharyngeal colonization of children 0–17years old was 21.2%.•Of 88 isolates, 16 were vaccine-type (11 were 19F), despite 87%…”
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L-plastin is essential for alveolar macrophage production and control of pulmonary pneumococcal infection by Deady, Lauren E, Todd, Elizabeth M, Davis, Chris G, Zhou, Julie Y, Topcagic, Nermina, Edelson, Brian T, Ferkol, Thomas W, Cooper, Megan A, Muenzer, Jared T, Morley, Sharon Celeste

“…We report that mice deficient for the hematopoietic-specific, actin-bundling protein L-plastin (LPL) succumb rapidly to intratracheal pneumococcal infection…”
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Inhaled GM-CSF in neonatal mice provides durable protection against bacterial pneumonia by Todd, Elizabeth M, Ramani, Rashmi, Szasz, Taylor P, Morley, S Celeste

“…Pneumonia poses profound health threats to preterm infants. Alveolar macrophages (AMs) eliminate inhaled pathogens while maintaining surfactant homeostasis. As…”
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Prevalence of nasopharyngeal pneumococcal colonization in children and antimicrobial susceptibility profiles of carriage isolates by Zhou, Julie Y, Isaacson-Schmid, Megan, Utterson, Elizabeth C, Todd, Elizabeth M, McFarland, Michelle, Sivapalan, Janardan, Niehoff, Joan M, Burnham, Carey-Ann D, Morley, S. Celeste

“…Highlights • The prevalence of pneumococcal colonization in a pediatric population in the USA is 34%. • The 13-valent pneumococcal conjugate vaccine (PCV13)…”
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Multiple Poisonings with Sodium Azide at a Local Restaurant by Schwarz, Evan S., MD, Wax, Paul M., MD, Kleinschmidt, Kurt C., MD, Sharma, Kapil, MD, Chung, Wendy M., MD, Cantu, Gabriela, MPH, Spargo, Erin, PhD, Todd, Elizabeth, PhD

“…Abstract Background Sodium azide is a chemical with a mechanism similar to cyanide. There is concern that it could be used as a chemical warfare agent…”
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Barbara Sizemore and the Politics of Black Educational Achievement and Community Control, 1963–1975 by Elizabeth Todd-Breland

“…Todd-Breland examines Barbara Sizemore and the politics of Black educational achievement and community control from 1963 to 1975. Sizemore was an African…”
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Impact of COVID-19 lockdown on A&E performances in an NHS Foundation Trust by Oomman, Sushrut, Todd, Elizabeth

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The Influence of Teachers' Efficacy and Beliefs Regarding Mathematics Instruction in the Early Childhood Classroom by Todd Brown, Elizabeth

“…This was a correlational study conducted with a population of prekindergarten educators from a large, metropolitan school district. The purpose was to examine…”
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Are Premature Infants with Bronchopulmonary Dysplasia Requiring Tracheostomy and Ventilation at Increased Risk of Atypical Craniosynostosis? by Martin, Suzanne, Ruiz, Ramon L., Stephens, Mark, Todd, Elizabeth, Golden, Brent, Jafrani, Ryan, Elbabaa, Samer, Martin, Suzanne

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