Search Results - "Todaro, R."

Medial prefrontal neuroplasticity during extended-release naltrexone treatment of opioid use disorder – a longitudinal structural magnetic resonance imaging study by Shi, Zhenhao, Li, Xinyi, Todaro, Dustin R., Cao, Wen, Lynch, Kevin G., Detre, John A., Loughead, James, Langleben, Daniel D., Wiers, Corinde E.

“…Opioid use disorder (OUD) has been linked to macroscopic structural alterations in the brain. The monthly injectable, extended-release formulation of μ-opioid…”
Get full text

Collateral Damage: Neurological Correlates of Non-Fatal Overdose in the Era of Fentanyl-Xylazine by Todaro, Dustin R, Volkow, Nora D, Langleben, Daniel D, Shi, Zhenhao, Wiers, Corinde E

“…Non-fatal opioid overdoses are associated with significant morbidity. Hypoxic brain injury caused by opioid-induced respiratory depression is a key mechanism…”
Get full text

Convergent Evolution in the Assembly of Polyubiquitin Degradation Signals by the Shigella flexneri IpaH9.8 Ligase by Edwards, Daniel J., Streich, Frederick C., Ronchi, Virginia P., Todaro, Dustin R., Haas, Arthur L.

“…The human pathogen Shigella flexneri subverts host function and defenses by deploying a cohort of effector proteins via a type III secretion system. The IpaH…”
Get full text

Cystic pancreatic neoplasms: diagnosis and management emphasizing their imaging features by Palmucci, S, Cappello, G, Trombatore, C, Tilocca, C, Todaro, R, Mauro, L A, Fisichella, R, Foti, P V, Milone, P, Ettorre, G C, Di Cataldo, A

“…The incidence of cystic pancreatic neoplasms increased in the past decade, due to the recent advances in multidetector computed tomography and magnetic…”
Get more information

Neurotoxic mechanisms by which the USP14 inhibitor IU1 depletes ubiquitinated proteins and Tau in rat cerebral cortical neurons: Relevance to Alzheimer's disease by Kiprowska, Magdalena J., Stepanova, Anna, Todaro, Dustin R., Galkin, Alexander, Haas, Arthur, Wilson, Scott M., Figueiredo-Pereira, Maria E.

“…In Alzheimer's disease proteasome activity is reportedly downregulated, thus increasing it could be therapeutically beneficial. The proteasome-associated…”
Get full text

Oligomerization of the HECT ubiquitin ligase NEDD4-2/NEDD4L is essential for polyubiquitin chain assembly by Todaro, Dustin R., Augustus-Wallace, Allison C., Klein, Jennifer M., Haas, Arthur L.

“…The NEDD4-2 (neural precursor cell–expressed developmentally down-regulated 4-2) HECT ligase catalyzes polyubiquitin chain assembly by an ordered two-step…”
Get full text

The mechanism of neural precursor cell expressed developmentally down-regulated 4-2 (Nedd4-2)/NEDD4L-catalyzed polyubiquitin chain assembly by Todaro, Dustin R., Augustus-Wallace, Allison C., Klein, Jennifer M., Haas, Arthur L.

“…The mechanism of Nedd4-2 has been quantitatively explored for the first time using biochemically defined kinetic assays examining rates of 125I-polyubiquitin…”
Get full text

Ketone Supplementation Dampens Subjective and Objective Responses to Alcohol: Evidence From a Preclinical Rat Study and a Randomized, Cross-Over Trial in Healthy Volunteers by Li, Xinyi, Shi, Zhenhao, Todaro, Dustin R, Pond, Timothy, Byanyima, Juliana I, Vesslee, Sianneh A, Reddy, Rishika, Nanga, Ravi Prakash Reddy, Kass, Gabriel, Ramchandani, Vijay, Kranzler, Henry R, Vendruscolo, Janaina C M, Vendruscolo, Leandro F, Wiers, Corinde E

“…Abstract Background Previous preclinical and human studies have shown that a high-fat ketogenic diet and ketone supplements (KS) are efficacious in reducing…”
Get full text

Methadone Dosing for Opioid Use Disorder in the Setting of Infective Endocarditis and QTc Prolongation by Todaro, Dustin R, Hoffman, Kevin W, Zwiebel, Samantha J

Get full text

Hippocampal volume loss in individuals with a history of non-fatal opioid overdose by Todaro, Dustin R, Li, Xinyi, Pereira-Rufino, Laís S, Manza, Peter, Nasrallah, Ilya M, Das, Sandhitsu, Childress, Anna Rose, Kranzler, Henry R, Volkow, Nora D, Langleben, Daniel D, Shi, Zhenhao, Wiers, Corinde E

“…Incidence of opioid-related overdoses in the United States has increased dramatically over the past two decades. Despite public emphasis on overdose…”
Get full text

Cytochrome rC552, Formed during Expression of the Truncated, Thermus thermophilus Cytochrome c552 Gene in the Cytoplasm of Escherichia coli, Reacts Spontaneously To Form Protein-Bound 2-Formyl-4-vinyl (Spirographis) Heme by FEE, James A., TODARO, Thomas R., LUNA, Eugene, SANDERS, Donita, HUNSICKER-WANG, Laura M., PATEL, Kirti M., BREN, Kara L., GOMEZ-MORAN, Ester, HILL, Michael G., AI, Jingyuan, LOEHR, Thomas M., OERTLING, W. Anthony, WILLIAMS, Pamela A., STOUT, C. David, MCREE, Duncan, PASTUSZYN, Andrzej

“…Expression of the truncated (lacking an N-terminal signal sequence) structural gene of Thermus thermophilus cytochrome c(552) in the cytoplasm of Escherichia…”
Get full text

Integrity of Thermus thermophilus cytochrome c552 synthesized by Escherichia coli cells expressing the host-specific cytochrome c maturation genes, ccmABCDEFGH: Biochemical, spectral, and structural characterization of the recombinant protein by FEE, JAMES A., CHEN, YING, TODARO, THOMAS R., BREN, KARA L., PATEL, KIRTI M., HILL, MICHAEL G., GOMEZ-MORAN, ESTER, LOEHR, THOMAS M., AI, JINGYUAN, THÖNY-MEYER, LINDA, WILLIAMS, PAMELA A., STURA, ENRICO, SRIDHAR, VANDANA, McREE, DUNCAN E.

“…We describe the design of Escherichia coli cells that synthesize a structurally perfect, recombinant cytochrome c from the Thermus thermophilus cytochrome c552…”
Get full text

Genetic variability in the ITS and IGS regions of the ribosomal DNA of Acremonium cavaraeanum exhibiting antimicrobial activity by Todaro, A R, Nascimento, V X, Souza, N C C, Silva, P P, Santos, J M, Ramalho, E A V F, Melo, T V C, Silva, I S M, Lins Júnior, G S, Bastos, M L A, Farias, D F, Souza, P C V, Carvalho, A F U, Silva, M C S, Almeida, R M R G, Ramalho Neto, E

“…Endophytic microorganisms represent promising alternatives for obtaining new drugs of biotechnological importance. In this study, the endophytic species…”
Get full text

Phylogenetic and biochemical studies of Thermus thermophilus respiratory proteins relevant to aerobic heterotrophy at hydrothermal vents : The archaeal-type cytochrome ba3 from strain HB8 is a sulphide resistant cytochrome c oxidase by FEE, J. A, TODARO, T. R, SANDERS, D

“…Our laboratory has been studying the respiratory proteins from Thermus thermophilus HB8 since the late 1970's, during which time we identified two cytochrome c…”
Get full text

Recombinant Cytochrome rC557 Obtained from Escherichia coli Cells Expressing a TruncatedThermus thermophilus cycA Gene by McRee, Duncan E., Williams, Pamela A., Sridhar, Vandana, Pastuszyn, Andrzej, Bren, Kara L., Patel, Kirti M., Chen, Ying, Todaro, Thomas R., Sanders, Donita, Luna, Eugene, Fee, James A.

“…Cytochrome rC557 is an improperly matured, dimeric cytochrome c obtained from expression of the “signal peptide-lacking” Thermus thermophilus cycA gene in the…”
Get full text

Cloning and Expression in Escherichia coli of the Cytochrome c 552 Gene from Thermus thermophilus HB8 by Keightley, J. Andrew, Sanders, Donita, Todaro, Thomas R., Pastuszyn, Andrzej, Fee, James A.

“…We report sequence of Thermus thermophilus HB8 DNA containing the gene ( cycA ) for cytochrome c 552 and a gene ( cycB ) encoding a protein homologous with one…”
Get full text

Cloning and expression in Escherichia coli of the cytochrome c552 gene from Thermus thermophilus HB8. Evidence for genetic linkage to an ATP-binding cassette protein and initial characterization of the cycA gene products by Keightley, J A, Sanders, D, Todaro, T R, Pastuszyn, A, Fee, J A

“…We report sequence of Thermus thermophilus HB8 DNA containing the gene (cycA) for cytochrome c552 and a gene (cycB) encoding a protein homologous with one…”
Get full text

Recombinant cytochrome rC557 obtained from Escherichia coli cells expressing a truncated Thermus thermophilus cycA gene. Heme inversion in an improperly matured protein by McRee, D E, Williams, P A, Sridhar, V, Pastuszyn, A, Bren, K L, Patel, K M, Chen, Y, Todaro, T R, Sanders, D, Luna, E, Fee, J A

“…Cytochrome rC(557) is an improperly matured, dimeric cytochrome c obtained from expression of the "signal peptide-lacking" Thermus thermophilus cycA gene in…”
Get full text

Cytochrome rC 552, Formed during Expression of the Truncated, Thermus thermophilus Cytochrome c 552 Gene in the Cytoplasm of Escherichia coli, Reacts Spontaneously To Form Protein-Bound 2-Formyl-4-vinyl (Spirographis) Heme by Fee, James A, Todaro, Thomas R, Luna, Eugene, Sanders, Donita, Hunsicker-Wang, Laura M, Patel, Kirti M, Bren, Kara L, Gomez-Moran, Ester, Hill, Michael G, Ai, Jingyuan, Loehr, Thomas M, Oertling, W. Anthony, Williams, Pamela A, Stout, C. David, McRee, Duncan, Pastuszyn, Andrzej

“…Expression of the truncated (lacking an N-terminal signal sequence) structural gene of Thermus thermophilus cytochrome c 552 in the cytoplasm of Escherichia…”
Get full text

(175) Safety of Rapid Methadone Titration for Opioid Use Disorder in Hospitalized Patients: A Pilot Study by Todaro, Dustin R., Casey, Emily, Thakrar, Ashish P., Uritsky, Tanya J., Zwiebel, Samantha

Get full text