Search Results - "Toda, Hiroko"
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Molecular pathogenesis of breast cancer: impact of miR-99a-5p and miR-99a-3p regulation on oncogenic genes
Published in Journal of human genetics (01-05-2021)“…Our recent research has revealed that passenger strands of certain microRNAs (miRNAs) function as tumor-suppressive miRNAs in cancer cells, e.g., miR-101-5p,…”
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Gene regulation by antitumor miR-130b-5p in pancreatic ductal adenocarcinoma: the clinical significance of oncogenic EPS8
Published in Journal of human genetics (01-06-2019)“…Our ongoing analyses identifying dysregulated microRNAs (miRNAs) and their controlled target RNAs have shed light on novel oncogenic pathways in pancreatic…”
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Molecular pathogenesis of pancreatic ductal adenocarcinoma: Impact of passenger strand of pre‐miR‐148a on gene regulation
Published in Cancer science (01-06-2018)“…We previously used RNA sequencing to establish the microRNA (miRNA) expression signature of pancreatic ductal adenocarcinoma (PDAC). We found that both strands…”
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Molecular pathogenesis of triple-negative breast cancer based on microRNA expression signatures: antitumor miR-204-5p targets AP1S3
Published in Journal of human genetics (01-12-2018)“…Triple-negative breast cancer (TNBC) is an aggressive type of cancer associated with a poor prognosis. Identification of novel therapeutic targets in TNBC is…”
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RNA‐sequence‐based microRNA expression signature in breast cancer: tumor‐suppressive miR‐101‐5p regulates molecular pathogenesis
Published in Molecular oncology (01-02-2020)“…Aberrantly expressed microRNA (miRNA) are known to disrupt intracellular RNA networks in cancer cells. Exploring miRNA‐dependent molecular networks is a major…”
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Oncoplastic breast surgery combining partial mastectomy with V-rotation mammoplasty for breast cancer on the upper inner area of the breast
Published in Surgery today (Tokyo, Japan) (01-07-2021)“…The treatment of early breast cancer using breast conservation therapy (BCT) commonly ensures local control and acceptable cosmetic results. We herein report a…”
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Oncoplastic breast surgery combining partial mastectomy with resection of double equilateral triangular skin flaps
Published in Surgery today (Tokyo, Japan) (01-03-2022)“…The treatment of early breast cancer using oncoplastic breast surgery (OBS) has been gradually increasing in popularity and is recognized for its efficacy in…”
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Atypical lymphoplasmacytic and immunoblastic proliferation: A Systematic Review
Published in Journal of Clinical and Experimental Hematopathology (01-01-2024)“…Atypical lymphoplasmacytic and immunoblastic proliferation (ALPIBP) was first reported in 1984 as characteristic histological findings in lymph nodes…”
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Modification of oncoplastic breast surgery with immediate volume replacement using a thoracodorsal adipofascial flap
Published in Breast cancer (Tokyo, Japan) (01-05-2022)“…Background The treatment of early breast cancer using breast conservation therapy (BCT) commonly ensures local control and acceptable cosmetic results. We…”
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Involvement of anti-tumor miR-124-3p and its targets in the pathogenesis of pancreatic ductal adenocarcinoma: direct regulation of ITGA3 and ITGB1 by miR-124-3p
Published in Oncotarget (22-06-2018)“…MicroRNAs (miRNAs) are unique in that a single miRNA molecule regulates a vast number of RNA transcripts. Thus, aberrantly expressed miRNAs disrupt tightly…”
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RNA-Sequencing Based microRNA Expression Signature of Colorectal Cancer: The Impact of Oncogenic Targets Regulated by miR-490-3p
Published in International journal of molecular sciences (13-09-2021)“…To elucidate novel aspects of the molecular pathogenesis of colorectal cancer (CRC), we have created a new microRNA (miRNA) expression signature based on…”
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Oncoplastic breast surgery combining partial mastectomy with a triangular skin resection and re-centralization of the nipple-areola
Published in Surgery today (Tokyo, Japan) (01-12-2020)“…The treatment of early breast cancer using breast conservation therapy (BCT) commonly ensures local control and acceptable cosmetic results. We herein report a…”
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A Rare Case of Pleural Epithelioid Mesothelioma With a Prominent Myxoid Stroma Reported With Morphology, Fluorescent In Situ Hybridization, and Ultrastructural Findings
Published in Curēus (Palo Alto, CA) (01-06-2024)“…Herein, we report a rare case of pleural epithelioid malignant mesothelioma with a prominent myxoid stroma. To date, detailed morphological or molecular…”
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Gene Regulation by Antitumor miR-204-5p in Pancreatic Ductal Adenocarcinoma: The Clinical Significance of Direct RACGAP1 Regulation
Published in Cancers (07-03-2019)“…Previously, we established a microRNA (miRNA) expression signature in pancreatic ductal adenocarcinoma (PDAC) tissues using RNA sequencing and found…”
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Upgraded bidirectional approach video-assisted neck surgery (BAVANS) using a rigid endoscope with variable viewing direction for advanced endoscopic lymph node dissection in thyroid cancer patients
Published in Surgery today (Tokyo, Japan) (01-07-2020)“…In 2011, we developed bidirectional approach video-assisted neck surgery (BAVANS) for endoscopic thyroid cancer surgery. BAVANS combines two different approach…”
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Multiple liver metastases with synchronous gastric and transverse colon cancer diagnosed by gastric perforation successfully treated by SOX plus bevacizumab and completely resected by surgery: a case report
Published in Surgical case reports (16-03-2020)“…Background Synchronous double cancer of the colon and stomach accompanied by liver metastasis is rare. It is often difficult to determine an appropriate…”
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Juvenile Granulosa Cell Tumor with an Unusual Clinical Course: A Late-onset and Late Recurrent Case
Published in Acta medica Okayama (01-04-2020)“…Juvenile granulosa cell tumors (JGCTs) are rare ovarian tumors with overall good prognoses. They differ from adult granulosa cell tumors (AGCTs), which are…”
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Clinicopathologic analysis of localized nasal/paranasal diffuse large B-cell lymphoma
Published in PloS one (28-02-2013)“…Diffuse large B-cell lymphoma (DLBCL) comprises 2 molecularly distinct subgroups of non-germinal center B-cell-like (non-GCB) and germinal center B-cell-like…”
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A Case of an Elderly Frail Patient with Unresectable Colorectal Cancer Controlled by Trifluridine/Tipiracil with Bevacizumab Therapy as a First-Line Treatment
Published in Gan to kagaku ryoho (01-02-2021)“…Although the effectiveness of trifluridine/tipiracil(TFTD)with bevacizumab for unresectable colorectal cancer that was refractory to previous standard…”
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Responses of Dorsal Spinal Cord Blood Flow to Noxious Mechanical Stimulation of the Skin in Anesthetized Rats
Published in Journal of Physiological Sciences (01-08-2008)“…In urethane-anesthetized, artificially ventilated rats, alterations in dorsal spinal cord blood flow (SCBF) at the L4–6 level were measured with laser Doppler…”
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