Search Results - "Tobin, Steven"

Molecular Imaging of HER2 in Patient Tissues with Touch Prep-Quantitative Single Molecule Localization Microscopy by Wakefield, Devin L, Tobin, Steven J, Schmolze, Daniel, Jovanovic-Talisman, Tijana

“…Biomolecules can be investigated at the nanoscale with quantitative single molecule localization microscopy (qSMLM). This technique, which achieves single…”
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Network flow model of force transmission in unbonded and bonded granular media by Tordesillas, Antoinette, Tobin, Steven T, Cil, Mehmet, Alshibli, Khalid, Behringer, Robert P

“…An established aspect of force transmission in quasistatic deformation of granular media is the existence of a dual network of strongly versus weakly loaded…”
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Single molecule localization microscopy coupled with touch preparation for the quantification of trastuzumab-bound HER2 by Tobin, Steven J., Wakefield, Devin L., Jones, Veronica, Liu, Xueli, Schmolze, Daniel, Jovanović-Talisman, Tijana

“…All breast cancers are assessed for levels of human epidermal growth factor receptor 2 (HER2). Fluorescence in situ hybridization (FISH) and…”
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Nanoscale effects of ethanol and naltrexone on protein organization in the plasma membrane studied by photoactivated localization microscopy (PALM) by Tobin, Steven J, Cacao, Eliedonna E, Hong, Daniel Wing Wo, Terenius, Lars, Vukojevic, Vladana, Jovanovic-Talisman, Tijana

“…Ethanol affects the signaling of several important neurotransmitter and neuromodulator systems in the CNS. It has been recently proposed that ethanol alters…”
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Molecular signatures of mu opioid receptor and somatostatin receptor 2 in pancreatic cancer by Jorand, Raphael, Biswas, Sunetra, Wakefield, Devin L, Tobin, Steven J, Golfetto, Ottavia, Hilton, Kelsey, Ko, Michelle, Ramos, Joe W, Small, Alexander R, Chu, Peiguo, Singh, Gagandeep, Jovanovic-Talisman, Tijana

“…Pancreatic ductal adenocarcinoma (PDAC), a particularly aggressive malignancy, has been linked to atypical levels, certain mutations, and aberrant signaling of…”
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A Platform To Enhance Quantitative Single Molecule Localization Microscopy by Golfetto, Ottavia, Wakefield, Devin L, Cacao, Eliedonna E, Avery, Kendra N, Kenyon, Victor, Jorand, Raphael, Tobin, Steven J, Biswas, Sunetra, Gutierrez, Jennifer, Clinton, Ronald, Ma, Yuelong, Horne, David A, Williams, John C, Jovanović-Talisman, Tijana

“…Quantitative single molecule localization microscopy (qSMLM) is a powerful approach to study in situ protein organization. However, uncertainty regarding the…”
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Dynamic lateral organization of opioid receptors (kappa, muwt and muN40D) in the plasma membrane at the nanoscale level by Rogacki, Maciej K., Golfetto, Ottavia, Tobin, Steven J., Li, Tianyi, Biswas, Sunetra, Jorand, Raphael, Zhang, Huiying, Radoi, Vlad, Ming, Yu, Svenningsson, Per, Ganjali, Daniel, Wakefield, Devin L., Sideris, Athanasios, Small, Alexander R., Terenius, Lars, Jovanović‐Talisman, Tijana, Vukojević, Vladana

“…Using quantitative methods with single‐molecule sensitivity, fluorescence correlation spectroscopy and photoactivated localization microscopy, we characterized…”
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Using quantitative single molecule localization microscopy to optimize multivalent HER2-targeting ligands by Wakefield, Devin L, Golfetto, Ottavia, Jorand, Raphael, Biswas, Sunetra, Meyer, Kassondra, Avery, Kendra N, Zer, Cindy, Cacao, Eliedonna E, Tobin, Steven J, Talisman, Ian J, Williams, John C, Jovanovic-Talisman, Tijana

“…The progression-free survival of patients with HER2-positive metastatic breast cancer is significantly extended by a combination of two monoclonal antibodies,…”
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Ethanol and Naltrexone Have Distinct Effects on the Lateral Nano-organization of Mu and Kappa Opioid Receptors in the Plasma Membrane by Tobin, Steven J, Wakefield, Devin L, Terenius, Lars, Vukojević, Vladana, Jovanović-Talisman, Tijana

“…The complex spatiotemporal organization of proteins and lipids in the plasma membrane is an important determinant of receptor function. Certain substances,…”
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Stick-slip and force chain evolution in a granular bed in response to a grain intruder by Tordesillas, Antoinette, Hilton, James E, Tobin, Steven T

“…The mechanical response of granular beds under applied stresses is often characterized by repeated cycles of stick-slip. Using the discrete element method, we…”
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Distribution of Cholesterol and HER2 in Patient Breast Cancer Cells using Quantitative Single Molecule Localization Microscopy by Brehove, Matthew S., Tobin, Steven J., Wakefield, Devin L., Jones, Veronica, Liu, Xueli, Schmolze, Daniel, Jovanović-Talisman, Tijana

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Molecular Assessment of HER2 in Breast Cancer by Maddox, Adam L., Brehove, Matthew S., Tobin, Steven J., Wakefield, Devin L., Eliato, Kiarash R., Alva-Ornelas, Jackelyn, Jones, Veronica, Schmolze, Daniel, Mortimer, Joanne, Seewaldt, Victoria L., Jovanovic-Talisman, Tijana

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Shear bands as bottlenecks in force transmission by Tordesillas, Antoinette, Pucilowski, Sebastian, Tobin, Steven, Kuhn, Matthew R., Andò, Edward, Viggiani, Gioacchino, Druckrey, Andrew, Alshibli, Khalid

“…The formation of shear bands is a key attribute of degradation and failure in soil, rocks, and many other forms of amorphous and crystalline materials…”
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A Quantitative Platform for Super-Resolution Microscopy Imaging by Golfetto, Ottavia, Wakefield, Devin L., Cacao, Eliedonna E., Avery, Kendra N., Jorand, Raphael, Tobin, Steven J., Clinton, Ronald M., Gutierrez, Jennifer, Ma, Yuelong, Ganjali, Daniel, Sideris, Athanasios, Horne, David A., Williams, John C., Jovanovic-Talisman, Tijana

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Applying Quantitative Super-Resolution Microscopy to Probe Molecular Organization of Membrane Proteins by Tobin, Steven Jeffrey

“…Super-resolution microscopy is a powerful technique that allows researchers to investigate cellular features with single molecule sensitivity and nanoscale…”
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Opioid Receptors are Organized into Nanodomains in the Plasma Membrane by Golfetto, Ottavia, Biswas, Sunetra, Jorand, Raphael, Zhang, Huiying, Jeffrey Tobin, Steven, Ganjali, Daniel, Sideris, Athanasios, Small, Alexander R., Vukojević, Vladana, Jovanović-Talisman, Tijana

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Molecular Signatures of G-Protein Coupled Receptors in Pancreatic Cancer using Super-Resolution Microscopy by Jorand, Raphael, Golfetto, Ottavia, Biswas, Sunetra, Tobin, Steven J., Zhang, Huiying, Vukojevic, Vladana, Jovanovic-Talisman, Tijana

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Nanoscale Effects of Ethanol and Naltrexone on Protein Organization in the Plasma Membrane Studied by Photoactivated Localization Microscopy (PALM): e87225 by Tobin, Steven J, Cacao, Eliedonna E, Hong, Daniel WingWo, Terenius, Lars, Vukojevic, Vladana, Jovanovic-Talisman, Tijana

“…Background Ethanol affects the signaling of several important neurotransmitter and neuromodulator systems in the CNS. It has been recently proposed that…”
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STUDIES IN THE SYNTHESIS OF DAUNOMYCIN AND ITS ANALOGS by TOBIN, PAUL STEVEN

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