Search Results - "Tobias, Nicholas J"

Aryl Polyenes, a Highly Abundant Class of Bacterial Natural Products, Are Functionally Related to Antioxidative Carotenoids by Schöner, Tim A., Gassel, Sören, Osawa, Ayako, Tobias, Nicholas J., Okuno, Yukari, Sakakibara, Yui, Shindo, Kazutoshi, Sandmann, Gerhard, Bode, Helge B.

“…Bacterial pigments of the aryl polyene type are structurally similar to the well‐known carotenoids with respect to their polyene systems. Their biosynthetic…”
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An Uncommon Type II PKS Catalyzes Biosynthesis of Aryl Polyene Pigments by Grammbitter, Gina L. C, Schmalhofer, Maximilian, Karimi, Kudratullah, Shi, Yi-Ming, Schöner, Tim A, Tobias, Nicholas J, Morgner, Nina, Groll, Michael, Bode, Helge B

“…Aryl polyene (APE) pigments are a widely distributed class of bacterial polyketides. So far, little is known about the biosynthesis of these compounds, which…”
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Marine sponge microbe provides insights into evolution and virulence of the tubercle bacillus by Pidot, Sacha J, Klatt, Stephan, Ates, Louis S, Frigui, Wafa, Sayes, Fadel, Majlessi, Laleh, Izumi, Hiroshi, Monk, Ian R, Porter, Jessica L, Bennett-Wood, Vicki, Seemann, Torsten, Otter, Ashley, Taiaroa, George, Cook, Gregory M, West, Nicholas, Tobias, Nicholas J, Fuerst, John A, Stutz, Michael D, Pellegrini, Marc, McConville, Malcolm, Brosch, Roland, Stinear, Timothy P

“…Reconstructing the evolutionary origins of Mycobacterium tuberculosis, the causative agent of human tuberculosis, has helped identify bacterial factors that…”
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Exposure to Trypanosoma parasites induces changes in the microbiome of the Chagas disease vector Rhodnius prolixus by Eberhard, Fanny E, Klimpel, Sven, Guarneri, Alessandra A, Tobias, Nicholas J

“…The causative agent of Chagas disease, Trypanosoma cruzi, and its nonpathogenic relative, Trypanosoma rangeli, are transmitted by haematophagous triatomines…”
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Screening of the Antimicrobial Activity against Drug Resistant Bacteria of Photorhabdus and Xenorhabdus Associated with Entomopathogenic Nematodes from Mae Wong National Park, Thailand by Muangpat, Paramaporn, Yooyangket, Temsiri, Fukruksa, Chamaiporn, Suwannaroj, Manawat, Yimthin, Thatcha, Sitthisak, Sutthirat, Chantratita, Narisara, Vitta, Apichat, Tobias, Nicholas J, Bode, Helge B, Thanwisai, Aunchalee

“…and are symbiotic with entomopathogenic nematodes (EPNs) of the genera and , respectively. These bacteria produce several secondary metabolites including…”
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Enzymatic biosynthesis of B-complex vitamins is supplied by diverse microbiota in the Rhodnius prolixus anterior midgut following Trypanosoma cruzi infection by Tobias, Nicholas J., Eberhard, Fanny E., Guarneri, Alessandra A.

“…[Display omitted] Trypanosoma cruzi, the causative agent of Chagas disease, colonizes the gut of triatomine insects, including Rhodnius prolixus. It is…”
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Multi-Omic Analysis of Symbiotic Bacteria Associated With Aedes aegypti Breeding Sites by Mosquera, Katherine D, Martinez Villegas, Luis E, Pidot, Sacha J, Sharif, Chinhda, Klimpel, Sven, Stinear, Timothy P, Moreira, Luciano A, Tobias, Nicholas J, Lorenzo, Marcelo G

“…Mosquito breeding sites are complex aquatic environments with wide microbial diversity and physicochemical parameters that can change over time during the…”
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Metabolites as predictive biomarkers for Trypanosoma cruzi exposure in triatomine bugs by Eberhard, Fanny E., Klimpel, Sven, Guarneri, Alessandra A., Tobias, Nicholas J.

“…[Display omitted] Trypanosoma cruzi, the causative agent of Chagas disease (American trypanosomiasis), colonizes the intestinal tract of triatomines…”
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Comparative analysis of the complete genome of an epidemic hospital sequence type 203 clone of vancomycin-resistant Enterococcus faecium by Lam, Margaret M C, Seemann, Torsten, Tobias, Nicholas J, Chen, Honglei, Haring, Volker, Moore, Robert J, Ballard, Susan, Grayson, Lindsay M, Johnson, Paul D R, Howden, Benjamin P, Stinear, Timothy P

“…In this report we have explored the genomic and microbiological basis for a sustained increase in bloodstream infections at a major Australian hospital caused…”
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Complete Genome Sequence of the Frog Pathogen Mycobacterium ulcerans Ecovar Liflandii by Tobias, Nicholas J, Doig, Kenneth D, Medema, Marnix H, Chen, Honglei, Haring, Volker, Moore, Robert, Seemann, Torsten, Stinear, Timothy P

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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High antibody titres induced by protein subunit vaccines using Mycobacterium ulcerans antigens Hsp18 and MUL_3720 with a TLR-2 agonist fail to protect against Buruli ulcer in mice by Mangas, Kirstie M, Tobias, Nicholas J, Marion, Estelle, Babonneau, Jérémie, Marsollier, Laurent, Porter, Jessica L, Pidot, Sacha J, Wong, Chinn Yi, Jackson, David C, Chua, Brendon Y, Stinear, Timothy P

“…is the causative agent of a debilitating skin and soft tissue infection known as Buruli ulcer (BU). There is no vaccine against BU. The purpose of this study…”
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Investigating the role of free-living amoebae as a reservoir for Mycobacterium ulcerans by Amissah, Nana Ama, Gryseels, Sophie, Tobias, Nicholas J, Ravadgar, Bahram, Suzuki, Mitsuko, Vandelannoote, Koen, Durnez, Lies, Leirs, Herwig, Stinear, Timothy P, Portaels, Françoise, Ablordey, Anthony, Eddyani, Miriam

“…The reservoir and mode of transmission of Mycobacterium ulcerans, the causative agent of Buruli ulcer, still remain a mystery. It has been suggested that M…”
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The cell wall-associated mycolactone polyketide synthases are necessary but not sufficient for mycolactone biosynthesis by Porter, Jessica L, Tobias, Nicholas J, Pidot, Sacha J, Falgner, Steffen, Tuck, Kellie L, Vettiger, Andrea, Hong, Hui, Leadlay, Peter F, Stinear, Timothy P

“…Mycolactones are polyketide-derived lipid virulence factors made by the slow-growing human pathogen, Mycobacterium ulcerans. Three unusually large and…”
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Whole genome comparisons suggest random distribution of Mycobacterium ulcerans genotypes in a Buruli ulcer endemic region of Ghana by Ablordey, Anthony S, Vandelannoote, Koen, Frimpong, Isaac A, Ahortor, Evans K, Amissah, Nana Ama, Eddyani, Miriam, Durnez, Lies, Portaels, Françoise, de Jong, Bouke C, Leirs, Herwig, Porter, Jessica L, Mangas, Kirstie M, Lam, Margaret M C, Buultjens, Andrew, Seemann, Torsten, Tobias, Nicholas J, Stinear, Timothy P

“…Efforts to control the spread of Buruli ulcer--an emerging ulcerative skin infection caused by Mycobacterium ulcerans--have been hampered by our poor…”
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Heterogeneous regulation of bacterial natural product biosynthesis via a novel transcription factor by Heinrich, Antje K., Glaeser, Angela, Tobias, Nicholas J., Heermann, Ralf, Bode, Helge B.

“…Biological diversity arises among genetically equal subpopulations in the same environment, a phenomenon called phenotypic heterogeneity. The life cycle of the…”
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Legionella shows a diverse secondary metabolism dependent on a broad spectrum Sfp-type phosphopantetheinyl transferase by Tobias, Nicholas J, Ahrendt, Tilman, Schell, Ursula, Miltenberger, Melissa, Hilbi, Hubert, Bode, Helge B

“…Several members of the genus cause Legionnaires' disease, a potentially debilitating form of pneumonia. Studies frequently focus on the abundant number of…”
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Snapshot fecal survey of domestic animals in rural Ghana for Mycobacterium ulcerans by Tobias, Nicholas J, Ammisah, Nana Ama, Ahortor, Evans K, Wallace, John R, Ablordey, Anthony, Stinear, Timothy P

“…Identifying the source reservoirs of Mycobacterium ulcerans is key to understanding the mode of transmission of this pathogen and controlling the spread of…”
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New Vocabulary for Bacterial Communication by Tobias, Nicholas J., Brehm, Jannis, Kresovic, Darko, Brameyer, Sophie, Bode, Helge B., Heermann, Ralf

“…Quorum sensing (QS) is widely accepted as a procedure that bacteria use to converse. However, prevailing thinking places acyl homoserine lactones (AHLs) at the…”
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Heterogeneity in Bacterial Specialized Metabolism by Tobias, Nicholas J., Bode, Helge B.

“…Specialized metabolites (SMs) like typical antibiotics, signaling molecules or other bioactive compounds of bacterial origin (sometimes also used in human…”
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Global analysis of biosynthetic gene clusters reveals conserved and unique natural products in entomopathogenic nematode-symbiotic bacteria by Shi, Yi-Ming, Hirschmann, Merle, Shi, Yan-Ni, Ahmed, Shabbir, Abebew, Desalegne, Tobias, Nicholas J., Grün, Peter, Crames, Jan J., Pöschel, Laura, Kuttenlochner, Wolfgang, Richter, Christian, Herrmann, Jennifer, Müller, Rolf, Thanwisai, Aunchalee, Pidot, Sacha J., Stinear, Timothy P., Groll, Michael, Kim, Yonggyun, Bode, Helge B.

“…Microorganisms contribute to the biology and physiology of eukaryotic hosts and affect other organisms through natural products. Xenorhabdus and Photorhabdus (…”
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