Search Results - "Tobia, A J"

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    In vitro and in vivo antibacterial activities of levofloxacin (l-ofloxacin), an optically active ofloxacin by FU, K. P, LAFREDO, S. C, FOLENO, B, ISAACSON, D. M, BARRETT, J. F, TOBIA, A. J, ROSENTHALE, M. E

    Published in Antimicrobial Agents and Chemotherapy (01-04-1992)
    “…ERRATUM ( vol. 36 , p. 1797 ) Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg…”
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    Using a Nonlinear Mixed Effects Model to Characterize Cholinesterase Activity in Rats Exposed to Aldicarb by Clayton, C. A., Starr, T. B., Sielken, R. L., Williams, R. L., P.-G. Pontal, Tobia, A. J.

    “…A statistical mixed effects model was applied to data from a two-phased experiment in which cholinesterase activity (CA) in red blood cells (RBCs) of rats was…”
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    6-Benzoxazinylpyridazin-3-ones: potent, long-acting positive inotrope and peripheral vasodilator agents by Combs, Donald W, Rampulla, Marianne S, Bell, Stanley C, Klaubert, Dieter H, Tobia, Alfonso J, Falotico, Robert, Haertlein, Barbara, Lakas-Weiss, Constance, Moore, John B

    Published in Journal of medicinal chemistry (01-01-1990)
    “…A series of 6-benzoxazinylpyridazin-3-ones was prepared and evaluated for inhibition of cardiac phosphodiesterase (PDE) fraction III in vitro and for positive…”
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    Bemoradan--a novel inhibitor of the rolipram-insensitive cyclic AMP phosphodiesterase from canine heart tissue by Moore, Jr, J B, Combs, D W, Tobia, A J

    Published in Biochemical pharmacology (15-07-1991)
    “…Canine cardiac muscle contains a type IV cyclic AMP (cAMP) phosphodiesterase (PDE) that is composed of two subtypes. One subtype is sensitive to rolipram…”
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    In-vivo evaluation of ofloxacin in Salmonella typhimurium infection in mice by Fu, K P, Hilliard, J, Isaacson, D, Tobia, A J, Rosenthale, M E, McGuire, J L

    Published in Journal of antimicrobial chemotherapy (01-02-1990)
    “…The effects of ofloxacin in Salmonella typhimurium infection in mice were compared with those of ciprofloxacin, ampicillin and chloramphenicol. Oral…”
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    Selective gastric antilesion properties of rioprostil, a prostaglandin E1 analog, in rats and dogs by Katz, L B, Shriver, D A, Tobia, A J, Rosenthale, M E

    “…This paper characterizes the ability of rioprostil, a synthetic primary alcohol prostaglandin E1 analog, to inhibit gastric acid secretion and prevent…”
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    Effects of ORF 17583, other histamine H2-receptor antagonists and omeprazole on gastric acid secretory states in rats and dogs by Katz, L B, Tobia, A J, Shriver, D A

    “…ORF 17583, a histamine H2-receptor antagonist, inhibited gastric acid secretion in pylorus-ligated rats (ED50 = 4.9 mg/kg intraduodenal; 3.4 mg/kg p.o.; and…”
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    Selective inhibition of 14 alpha-desmethyl sterol synthesis in Candida albicans by terconazole, a new triazole antimycotic by Isaacson, D M, Tolman, E L, Tobia, A J, Rosenthale, M E, McGuire, J L, Vanden Bossche, H, Janssen, P A

    Published in Journal of antimicrobial chemotherapy (01-03-1988)
    “…Terconazole, a new broad spectrum antimycotic triazole derivative, has been shown to have potent activity against Candida albicans in vitro and to be effective…”
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    Positive inotropic and hemodynamic properties of flosequinan, a new vasodilator, and a sulfone metabolite by Falotico, R, Haertlein, B J, Lakas-Weiss, C S, Salata, J J, Tobia, A J

    Published in Journal of cardiovascular pharmacology (01-09-1989)
    “…Flosequinan, a new orally active vasodilator, and its sulfone metabolite were evaluated for inotropic activity in isolated ferret papillary muscles and…”
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    Cardiotonic agents. Synthesis and inotropic activity of a series of isoquinolin-3-ol derivatives by Kanojia, Ramesh M, Press, Jeffery B, Lever, O. William, Williams, Louella, McNally, James J, Tobia, Alfonso J, Falotico, Robert, Moore, John B

    Published in Journal of medicinal chemistry (01-07-1988)
    “…A series of isoquinolin-3-ol derivatives (II) was prepared as analogues of the clinical cardiotonic agent bemarinone (ORF 16600, I). Although in many respects…”
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    Altered hemodynamic responses to acute hypoxemia in spontaneously hypertensive rats by Walsh, G M, Tsuchiya, M, Cox, A C, Tobia, A J, Frohlich, E D

    Published in The American journal of physiology (01-03-1978)
    “…Conscious spontaneously hypertensive rats (SHR), 5--7 wk old, were studied hemodynamically by the direct Fick procedure to determine whether high total…”
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    Antifertility activity and general pharmacological properties of ORF 13811: a synthetic analog of zoapatanol by Hahn, D W, Tobia, A J, Rosenthale, M E, McGuire, J L

    Published in Contraception (Stoneham) (01-07-1984)
    “…ORF 13811, a synthetic analog of zoapatanol, was evaluated in a variety of in vivo and in vitro biological test systems to determine antifertility and…”
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    The effects of the quinone type drugs on hydroxyl radical (OH.) production by rat liver microsomes by Tobia, A J, Couri, D, Sagone, A

    “…The quinone drugs are known to be metabolized to semiquinone free-radical intermediates and to enhance NADPH oxidation in microsomal system. The effect of…”
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