Search Results - "Tobia, A J"
-
1
In vitro and in vivo antibacterial activities of levofloxacin (l-ofloxacin), an optically active ofloxacin
Published in Antimicrobial Agents and Chemotherapy (01-04-1992)“…ERRATUM ( vol. 36 , p. 1797 ) Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg…”
Get full text
Journal Article -
2
Using a Nonlinear Mixed Effects Model to Characterize Cholinesterase Activity in Rats Exposed to Aldicarb
Published in Journal of agricultural, biological, and environmental statistics (01-12-2003)“…A statistical mixed effects model was applied to data from a two-phased experiment in which cholinesterase activity (CA) in red blood cells (RBCs) of rats was…”
Get full text
Journal Article -
3
6-Benzoxazinylpyridazin-3-ones: potent, long-acting positive inotrope and peripheral vasodilator agents
Published in Journal of medicinal chemistry (01-01-1990)“…A series of 6-benzoxazinylpyridazin-3-ones was prepared and evaluated for inhibition of cardiac phosphodiesterase (PDE) fraction III in vitro and for positive…”
Get full text
Journal Article -
4
Bemoradan--a novel inhibitor of the rolipram-insensitive cyclic AMP phosphodiesterase from canine heart tissue
Published in Biochemical pharmacology (15-07-1991)“…Canine cardiac muscle contains a type IV cyclic AMP (cAMP) phosphodiesterase (PDE) that is composed of two subtypes. One subtype is sensitive to rolipram…”
Get more information
Journal Article -
5
In-vivo evaluation of ofloxacin in Salmonella typhimurium infection in mice
Published in Journal of antimicrobial chemotherapy (01-02-1990)“…The effects of ofloxacin in Salmonella typhimurium infection in mice were compared with those of ciprofloxacin, ampicillin and chloramphenicol. Oral…”
Get more information
Journal Article -
6
Selective gastric antilesion properties of rioprostil, a prostaglandin E1 analog, in rats and dogs
Published in The Journal of pharmacology and experimental therapeutics (01-09-1987)“…This paper characterizes the ability of rioprostil, a synthetic primary alcohol prostaglandin E1 analog, to inhibit gastric acid secretion and prevent…”
Get more information
Journal Article -
7
Effects of ORF 17583, other histamine H2-receptor antagonists and omeprazole on gastric acid secretory states in rats and dogs
Published in The Journal of pharmacology and experimental therapeutics (01-08-1987)“…ORF 17583, a histamine H2-receptor antagonist, inhibited gastric acid secretion in pylorus-ligated rats (ED50 = 4.9 mg/kg intraduodenal; 3.4 mg/kg p.o.; and…”
Get more information
Journal Article -
8
Selective inhibition of 14 alpha-desmethyl sterol synthesis in Candida albicans by terconazole, a new triazole antimycotic
Published in Journal of antimicrobial chemotherapy (01-03-1988)“…Terconazole, a new broad spectrum antimycotic triazole derivative, has been shown to have potent activity against Candida albicans in vitro and to be effective…”
Get more information
Journal Article -
9
Positive inotropic and hemodynamic properties of flosequinan, a new vasodilator, and a sulfone metabolite
Published in Journal of cardiovascular pharmacology (01-09-1989)“…Flosequinan, a new orally active vasodilator, and its sulfone metabolite were evaluated for inotropic activity in isolated ferret papillary muscles and…”
Get more information
Journal Article -
10
Synthesis and renal vasodilator activity of some dopamine agonist 1-aryl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diols: halogen and methyl analogs of fenoldopam
Published in Journal of medicinal chemistry (01-11-1986)“…Certain 6-halo-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines were found to be potent D-1 dopamine agonists. The 1-(4-hydroxyphenyl) analogues did not have…”
Get full text
Journal Article -
11
Cardiotonic agents. Synthesis and inotropic activity of a series of isoquinolin-3-ol derivatives
Published in Journal of medicinal chemistry (01-07-1988)“…A series of isoquinolin-3-ol derivatives (II) was prepared as analogues of the clinical cardiotonic agent bemarinone (ORF 16600, I). Although in many respects…”
Get full text
Journal Article -
12
Altered hemodynamic responses to acute hypoxemia in spontaneously hypertensive rats
Published in The American journal of physiology (01-03-1978)“…Conscious spontaneously hypertensive rats (SHR), 5--7 wk old, were studied hemodynamically by the direct Fick procedure to determine whether high total…”
Get full text
Journal Article -
13
Renal vasodilators. The role of the 4-substituent in isoquinolin-3-ol cardiovascular agents. 4-Ureido derivatives of isoquinolin-3-ol with selective renal vasodilator properties
Published in Journal of medicinal chemistry (01-05-1989)“…The synthesis and cardiovascular evaluation of a series of isoquinolin-3-ol derivatives bearing a variety of nitrogen substituents (amino, acylamino,…”
Get full text
Journal Article -
14
The metabolism of betahistine in the rat
Published in Drug metabolism and disposition (01-03-1974)Get more information
Journal Article -
15
Renal vasodilator responses to captopril in dogs pretreated with indomethacin
Published in Proceedings of the Society for Experimental Biology and Medicine (01-06-1981)Get more information
Journal Article -
16
Antifertility activity and general pharmacological properties of ORF 13811: a synthetic analog of zoapatanol
Published in Contraception (Stoneham) (01-07-1984)“…ORF 13811, a synthetic analog of zoapatanol, was evaluated in a variety of in vivo and in vitro biological test systems to determine antifertility and…”
Get more information
Journal Article -
17
Altered reflex vasodilatation in the hypertensive rat: possible role of histamine
Published in The Journal of pharmacology and experimental therapeutics (01-12-1970)Get more information
Journal Article -
18
The effects of the quinone type drugs on hydroxyl radical (OH.) production by rat liver microsomes
Published in Journal of toxicology and environmental health (1985)“…The quinone drugs are known to be metabolized to semiquinone free-radical intermediates and to enhance NADPH oxidation in microsomal system. The effect of…”
Get more information
Journal Article -
19
The role of demethylbetahistine in the depressor response to betahistine in the rat
Published in Proceedings of the Society for Experimental Biology and Medicine (01-03-1974)Get more information
Journal Article -
20
Regional blood flow and vascular resistance in the spontaneously hypertensive rat
Published in Cardiovascular research (01-11-1974)Get more information
Journal Article