Search Results - "Tobal, K"

550 p53 Mutations Are Common in Iraqi Children With Medulloblastomas and Ependymomas – Indication of a Different Disease Etiology and Prognosis by Al Obaidi, L, Alansari, N, Yaseen, N, Mohammed, H, Tobal, K

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549 RAF Fusion Transcripts Detected in Medulloblastoma but not Ependymoma Using RT-RQPCR Assays on RNA Isolated From FFPE Tissues by Al Obaidi, L, Alansari, N, Yaseen, N, Mohammed, H, Tobal, K

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13 Acquired resistance to EGFR inhibition: evolution from adenocarcinoma to small cell lung cancer (SCLC) by Moss, C, Cane, P, Mclean, E, Santis, G, Tobal, K, Spicer, J

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6 Microdroplet digital PCR in detecting mutational events in cell-free DNA in patients with lung cancer – a pilot study by Gao, F, Dua, D, Pfeifer, E, Farah, H, Tobal, K, Cane, P, Spicer, J, McCaughan, F

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8: Tumour molecular profiling and quantitative detection of circulating biomarkers in patients with lung cancer by Karampini, E, Farah, H, Mills, G, Kamal, N, Tobal, K, Cane, P, Muirhead, J, Pomplun, S, King, J.E, Sethi, T, McCaughan, F, Spicer, J

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Development of standardized approaches to reporting of minimal residual disease data using a reporting software package designed within the European LeukemiaNet by Østergaard, M, Nyvold, C G, Jovanovic, J V, Andersen, M T, Kairisto, V, Morgan, Y G, Tobal, K, Pallisgaard, N, Özbek, U, Pfeifer, H, Schnittger, S, Grubach, L, Larsen, J K, Grimwade, D, Hokland, P

“…Quantitative PCR (qPCR) for detection of fusion transcripts and overexpressed genes is a promising tool for following minimal residual disease (MRD) in…”
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46 Prevalence of EGFR and K-RAS mutation status in clinical practice - relationship to patient characteristics by Simpson, T, Pennycuick, A, Crawley, D, Tobal, K, Santis, G

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Molecular quantitation of minimal residual disease in acute myeloid leukemia with t(8;21) can identify patients in durable remission and predict clinical relapse by Tobal, K., Newton, J., Macheta, M., Chang, J., Morgenstern, G., Evans, P. A.S., Morgan, G., Lucas, G.S., Yin, J. A. Liu

“…One of the most common translocations in acute myeloid leukemia (AML) is the t(8;21), which produces the fusion gene AML1-MTG8. We have developed a sensitive…”
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Elevated levels of WT1 transcripts in bone marrow harvests are associated with a high relapse risk in patients autografted for acute myeloid leukaemia by OSBORNE, D, FROST, L, TOBAL, K, LIU YIN, J. A

“…Relapse postautograft in acute myeloid leukaemia (AML), may in part arise from leukaemia cells present in the bone marrow (BM) inoculum, and the level of…”
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RT-PCR method with increased sensitivity shows persistence of PML-RARA fusion transcripts in patients in long-term remission of APL by TOBAL, K, LIU YIN, J. A

“…RT-PCR methods have been developed, to date, by various groups to amplify the PML-RARA fusion gene produced by the t(15;17) in APL patients. However, these…”
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Monitoring minimal residual disease and predicting relapse in APL by quantitating PML-RARα transcripts with a sensitive competitive RT-PCR method by TOBAL, K, MOORE, H, MACHETA, M, IA LIU YIN

“…Qualitative RT-PCR methods used for monitoring minimal residual disease (MRD) in APL patients fail to predict relapse in up to 25% of patients in remission. We…”
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Quantitation of PML-RARα transcripts in APL patients by Tobal, K

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The diagnosis of delayed post-operative endophthalmitis by polymerase chain reaction of bacterial DNA in vitreous samples by Hykin, P. G, Tobal, K, McIntyre, G, Matheson, M. M, Towler, H. M. A, Lightman, S. L

“…1 Departments of Clinical Science, Institute of Ophthalmology, Bath Street, London EC1V 9EL * Department of Medical Microbiology. University College London…”
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Detection of CBFB/MYH11 transcripts in patients with inversion and other abnormalities of chromosome 16 at presentation and remission by Tobal, K, Johnson, P R, Saunders, M J, Harrison, C J, Liu Yin, J A

“…The pericentric inversion of chromosome 16 [inv(16)(p13q22)] and t(16;16)(p13;q22) are chromosomal rearrangements frequently associated with AML FAB type M4Eo…”
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601TiP First-in-human phase I study of a novel oral Wee1 inhibitor (Debio 0123) in combination with carboplatin in patients with advanced solid tumours by Gelderblom, H., Gietema, J.A., Desar, I.M.E., Ajmone, N.M., Jalving, M., Kroep, J.R., Nicolas, V., Vaslin, A., Tobal, K., Purcea, D., van Haren, S.F., Damstrup, L.

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Detection and quantitation of the CBFβ/MYH11 transcripts associated with the inv(16) in presentation and follow-up samples from patients with AML by EVANS, P. A. S, SHORT, M. A, JACK, A. S, NORFOLK, D. R, CHILD, J. A, SHIACH, C. R, DAVIES, F, TOBAL, K, YIN, J. A. L, MORGAN, G. J

“…We have developed a competitor-based RT-PCR technique which will detect and quantitate the CBFβ/MYH11 transcripts associated with inv(16)(q22;p13) and have…”
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Establishing optimal quantitative-polymerase chain reaction assays for routine diagnosis and tracking of minimal residual disease in JAK2-V617F-associated myeloproliferative neoplasms: a joint European LeukemiaNet/MPN&MPNr-EuroNet (COST action BM0902) study by Jovanovic, J V, Ivey, A, Vannucchi, A M, Lippert, E, Oppliger Leibundgut, E, Cassinat, B, Pallisgaard, N, Maroc, N, Hermouet, S, Nickless, G, Guglielmelli, P, van der Reijden, B A, Jansen, J H, Alpermann, T, Schnittger, S, Bench, A, Tobal, K, Wilkins, B, Cuthill, K, McLornan, D, Yeoman, K, Akiki, S, Bryon, J, Jeffries, S, Jones, A, Percy, M J, Schwemmers, S, Gruender, A, Kelley, T W, Reading, S, Pancrazzi, A, McMullin, M F, Pahl, H L, Cross, N C P, Harrison, C N, Prchal, J T, Chomienne, C, Kiladjian, J J, Barbui, T, Grimwade, D

“…Reliable detection of JAK2 -V617F is critical for accurate diagnosis of myeloproliferative neoplasms (MPNs); in addition, sensitive mutation-specific assays…”
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Increased expression and mutation of p53 in choroidal melanoma by TOBAL, K, WARREN, W, COOPER, C. S, MCCARTNEY, A, HUNGERFORD, J, LIGHTMAN, S

“…Using CM-1 antibody directed against the human p53 protein, high levels of mutant p53 protein expression were found in 12 out of 18 malignant choroidal…”
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Detection of melanocytes from uveal melanoma in peripheral blood using the polymerase chain reaction by Tobal, K, Sherman, LS, Foss, AJ, Lightman, SL

“…Uveal melanoma is the most common intraocular malignancy in adults and can cause loss of vision in the affected eye and death from metastasis, usually to the…”
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Mutation of the human FMS gene (M-CSF receptor) in myelodysplastic syndromes and acute myeloid leukemia by Tobal, K, Pagliuca, A, Bhatt, B, Bailey, N, Layton, D M, Mufti, G J

“…We studied 41 patients with myelodysplastic syndromes or acute myeloid leukemia to assess the presence of point mutations in the human FMS gene (M-CSF…”
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