Search Results - "To, Jesi Y"

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  1. 1

    Activated heterotrimeric G protein αi subunits inhibit Rap-dependent cell adhesion and promote cell migration by To, Jesi Y., Smrcka, Alan V.

    Published in The Journal of biological chemistry (02-02-2018)
    “…Our recent work uncovered novel roles for activated Gαi signaling in the regulation of neutrophil polarity and adhesion. GαiGTP-mediated enhancement of…”
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    Journal Article
  2. 2

    Dynamic regulation of neutrophil polarity and migration by the heterotrimeric G protein subunits Gαi-GTP and Gβγ by Surve, Chinmay R, To, Jesi Y, Malik, Sundeep, Kim, Minsoo, Smrcka, Alan V

    Published in Science signaling (23-02-2016)
    “…Activation of the Gi family of heterotrimeric guanine nucleotide-binding proteins (G proteins) releases βγ subunits, which are the major transducers of…”
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    Journal Article
  3. 3

    Inhibition of G Protein βγ Subunit Signaling Abrogates Nephritis in Lupus‐Prone Mice by Rangel‐Moreno, Javier, To, Jesi Y., Owen, Teresa, Goldman, Bruce I., Smrcka, Alan V., Anolik, Jennifer H.

    Published in Arthritis & rheumatology (Hoboken, N.J.) (01-09-2016)
    “…Objective Despite considerable advances in the understanding of systemic lupus erythematosus (SLE), there is still an urgent need for new and more targeted…”
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    Journal Article
  4. 4

    Inhibition of G Protein beta gamma Subunit Signaling Abrogates Nephritis in Lupus-Prone Mice by Rangel-Moreno, Javier, To, Jesi Y, Owen, Teresa, Goldman, Bruce I, Smrcka, Alan V, Anolik, Jennifer H

    Published in Arthritis & rheumatology (Hoboken, N.J.) (01-09-2016)
    “…Objective Despite considerable advances in the understanding of systemic lupus erythematosus (SLE), there is still an urgent need for new and more targeted…”
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    Journal Article
  5. 5

    Inhibition of G Protein [beta][gamma] Subunit Signaling Abrogates Nephritis in Lupus-Prone Mice by Rangel-Moreno, Javier, To, Jesi Y, Owen, Teresa, Goldman, Bruce I, Smrcka, Alan V, Anolik, Jennifer H

    Published in Arthritis & rheumatology (Hoboken, N.J.) (01-09-2016)
    “…Objective Despite considerable advances in the understanding of systemic lupus erythematosus (SLE), there is still an urgent need for new and more targeted…”
    Get full text
    Journal Article
  6. 6

    The Importance of G Protein Signaling in Immune Cell Function: A Novel Role for Active Gαi in Cell Adhesion and Migration and the Therapeutic Potential of Targeting Gβγ in Inflammation by To, Jesi Lee Anne Y

    Published 01-01-2018
    “…Chemotaxis is the directional movement of cells towards a gradient of chemoattractant such as chemokines. Chemokines are small peptides secreted by various…”
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    Dissertation